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Endothelial K Ca 3.1 and K Ca 2.3 Mediate S1P (Sphingosine-1-Phosphate)-Dependent Vasodilation and Blood Pressure Homeostasis.

Autor: Li JJ; The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Shaanxi, China (J.-J.L., R.X., X.-H.D., L.X., J.Z., W.X.)., Zhao XY; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, and Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education, Xi'an Jiaotong University Health Science Center, Shaanxi, China (X.-Y.Z., Y.W., Y.Z., M.-Z.H., R.-Y.B., Z.-D.P., X.-J.D., X.-L.D., Y.Z.)., Wang Y; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, and Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education, Xi'an Jiaotong University Health Science Center, Shaanxi, China (X.-Y.Z., Y.W., Y.Z., M.-Z.H., R.-Y.B., Z.-D.P., X.-J.D., X.-L.D., Y.Z.)., Xu R; The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Shaanxi, China (J.-J.L., R.X., X.-H.D., L.X., J.Z., W.X.)., Di XH; The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Shaanxi, China (J.-J.L., R.X., X.-H.D., L.X., J.Z., W.X.)., Zhang Y; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, and Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education, Xi'an Jiaotong University Health Science Center, Shaanxi, China (X.-Y.Z., Y.W., Y.Z., M.-Z.H., R.-Y.B., Z.-D.P., X.-J.D., X.-L.D., Y.Z.)., Yang H; Department of Aerospace Medicine, Fourth Military Medical University, Xi'an, Shaanxi, China (H.Y., X.Z.)., Han MZ; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, and Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education, Xi'an Jiaotong University Health Science Center, Shaanxi, China (X.-Y.Z., Y.W., Y.Z., M.-Z.H., R.-Y.B., Z.-D.P., X.-J.D., X.-L.D., Y.Z.)., Bai RY; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, and Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education, Xi'an Jiaotong University Health Science Center, Shaanxi, China (X.-Y.Z., Y.W., Y.Z., M.-Z.H., R.-Y.B., Z.-D.P., X.-J.D., X.-L.D., Y.Z.)., Xie L; The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Shaanxi, China (J.-J.L., R.X., X.-H.D., L.X., J.Z., W.X.)., Pang ZD; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, and Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education, Xi'an Jiaotong University Health Science Center, Shaanxi, China (X.-Y.Z., Y.W., Y.Z., M.-Z.H., R.-Y.B., Z.-D.P., X.-J.D., X.-L.D., Y.Z.)., Zhang X; Department of Aerospace Medicine, Fourth Military Medical University, Xi'an, Shaanxi, China (H.Y., X.Z.)., Zhang J; The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Shaanxi, China (J.-J.L., R.X., X.-H.D., L.X., J.Z., W.X.)., Du XJ; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, and Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education, Xi'an Jiaotong University Health Science Center, Shaanxi, China (X.-Y.Z., Y.W., Y.Z., M.-Z.H., R.-Y.B., Z.-D.P., X.-J.D., X.-L.D., Y.Z.)., Deng XL; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, and Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education, Xi'an Jiaotong University Health Science Center, Shaanxi, China (X.-Y.Z., Y.W., Y.Z., M.-Z.H., R.-Y.B., Z.-D.P., X.-J.D., X.-L.D., Y.Z.)., Zhang Y; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, and Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education, Xi'an Jiaotong University Health Science Center, Shaanxi, China (X.-Y.Z., Y.W., Y.Z., M.-Z.H., R.-Y.B., Z.-D.P., X.-J.D., X.-L.D., Y.Z.)., Xie W; The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Shaanxi, China (J.-J.L., R.X., X.-H.D., L.X., J.Z., W.X.).; Department of Aerospace Medicine, Fourth Military Medical University, Xi'an, Shaanxi, China (H.Y., X.Z.).

Publikováno v: Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2023 May; Vol. 43 (5), pp. 726-738. Date of Electronic Publication: 2023 Mar 23.

AGEs-RAGE-K Ca 3.1 pathway mediates palmitic acid-induced migration of PBMCs from patients with type 2 diabetes.

Autor: Zhang Y; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, 76 West Yanta Road, Xi'an, 710061, Shaanxi, China., Ma XZ; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, 76 West Yanta Road, Xi'an, 710061, Shaanxi, China., Zhao XY; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, 76 West Yanta Road, Xi'an, 710061, Shaanxi, China., Li JJ; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, 76 West Yanta Road, Xi'an, 710061, Shaanxi, China., Ma S; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, 76 West Yanta Road, Xi'an, 710061, Shaanxi, China.; Department of Endocrinology, The Second Affiliated Hospital, Xi'an Jiaotong University, 157 Fifth West Road, Xi'an, 710004, Shaanxi, China., Pang ZD; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, 76 West Yanta Road, Xi'an, 710061, Shaanxi, China., Xu J; Department of Endocrinology, The Second Affiliated Hospital, Xi'an Jiaotong University, 157 Fifth West Road, Xi'an, 710004, Shaanxi, China., Du XJ; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, 76 West Yanta Road, Xi'an, 710061, Shaanxi, China., Deng XL; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, 76 West Yanta Road, Xi'an, 710061, Shaanxi, China., Wang JH; Department of Endocrinology, The Second Affiliated Hospital, Xi'an Jiaotong University, 157 Fifth West Road, Xi'an, 710004, Shaanxi, China.; Department of Endocrinology, Gongli Hospital, Pudong New Area, Shanghai, 200135, China.

Publikováno v: Heliyon [Heliyon] 2023 Mar 24; Vol. 9 (4), pp. e14823. Date of Electronic Publication: 2023 Mar 24 (Print Publication: 2023).

Hippo pathway activation mediates chemotherapy-induced anti-cancer effect and cardiomyopathy through causing mitochondrial damage and dysfunction.

Autor: She G; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, 76 West Yanta Road, Xi'an, 710061, Shaanxi, China., Du JC; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, 76 West Yanta Road, Xi'an, 710061, Shaanxi, China., Wu W; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, 76 West Yanta Road, Xi'an, 710061, Shaanxi, China., Pu TT; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, 76 West Yanta Road, Xi'an, 710061, Shaanxi, China., Zhang Y; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, 76 West Yanta Road, Xi'an, 710061, Shaanxi, China., Bai RY; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, 76 West Yanta Road, Xi'an, 710061, Shaanxi, China., Zhang Y; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, 76 West Yanta Road, Xi'an, 710061, Shaanxi, China., Pang ZD; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, 76 West Yanta Road, Xi'an, 710061, Shaanxi, China., Wang HF; Department of Pathology, Xi'an People's Hospital (Xi'an Fourth Hospital), Affiliated Guangren Hospital, Xi'an Jiaotong University Health Science Center, 21 Jiefang Road, Xi'an, 710005, Shaanxi, China., Ren YJ; Department of Pathology, Xi'an People's Hospital (Xi'an Fourth Hospital), Affiliated Guangren Hospital, Xi'an Jiaotong University Health Science Center, 21 Jiefang Road, Xi'an, 710005, Shaanxi, China., Sadoshima J; Rutgers New Jersey Medical School, Department of Cell Biology and Molecular Medicine, New Jersey, United States of America., Deng XL; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, 76 West Yanta Road, Xi'an, 710061, Shaanxi, China.; Cardiovascular Research Centre, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, 76 West Yanta Road, Xi'an, 710061, Shaanxi, China., Du XJ; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, 76 West Yanta Road, Xi'an, 710061, Shaanxi, China.; Baker Heart and Diabetes Institute, 75 Commercial Road, Melbourne, Victoria 3004, Australia.

Publikováno v: Theranostics [Theranostics] 2023 Jan 01; Vol. 13 (2), pp. 560-577. Date of Electronic Publication: 2023 Jan 01 (Print Publication: 2023).

Activation of Hippo signaling pathway mediates mitochondria dysfunction and dilated cardiomyopathy in mice.

Autor: Wu W; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, and Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education, Xian Jiaotong University Health Science Center, Xian, China., Ziemann M; School of Life and Environmental Sciences, Deakin University, Geelong, Victoria, Australia., Huynh K; Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia., She G; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, and Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education, Xian Jiaotong University Health Science Center, Xian, China., Pang ZD; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, and Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education, Xian Jiaotong University Health Science Center, Xian, China., Zhang Y; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, and Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education, Xian Jiaotong University Health Science Center, Xian, China., Duong T; Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia., Kiriazis H; Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia., Pu TT; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, and Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education, Xian Jiaotong University Health Science Center, Xian, China., Bai RY; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, and Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education, Xian Jiaotong University Health Science Center, Xian, China., Li JJ; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, and Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education, Xian Jiaotong University Health Science Center, Xian, China., Zhang Y; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, and Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education, Xian Jiaotong University Health Science Center, Xian, China., Chen MX; Center of Electron Microscopy, Xian Jiaotong University Health Science Center, Xian, China., Sadoshima J; New Jersey Medical School, Department of Cell Biology and Molecular Medicine Rutgers, New Jersey, United States of America., Deng XL; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, and Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education, Xian Jiaotong University Health Science Center, Xian, China., Meikle PJ; Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia., Du XJ; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, and Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education, Xian Jiaotong University Health Science Center, Xian, China.; Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.

Publikováno v: Theranostics [Theranostics] 2021 Aug 21; Vol. 11 (18), pp. 8993-9008. Date of Electronic Publication: 2021 Aug 21 (Print Publication: 2021).