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of 4
pro vyhledávání: '"Pang Yuk Cheung"'
Publikováno v:
Cells, Vol 11, Iss 1, p 6 (2021)
The development over the past 50 years of a variety of cell lines and animal models has provided valuable tools to understand the pathophysiology of nephropathic cystinosis. Primary cultures from patient biopsies have been instrumental in determining
Externí odkaz:
https://doaj.org/article/eb8edd33e5e940d58fa9a0acf5d8098a
Autor:
Jennifer A. Hollywood, Prasanna K. Kallingappa, Pang Yuk Cheung, Renita M. Martis, Sree Sreebhavan, Robert D. ‘Atiola, Aparajita Chatterjee, Emma J. Buckels, Brya G. Matthews, Paula M. Lewis, Alan J. Davidson
Publikováno v:
American Journal of Physiology-Renal Physiology. 323:F156-F170
Animal models of disease are essential to perform preclinical testing of new therapies before they can progress to clinical trials. The cystinosis field has been hampered by a lack of suitable animal models that fully recapitulate the disease. Here,
Autor:
Jennifer A. Hollywood, Alan J. Davidson, Paula M. Lewis, Brya G. Matthews, Emma J Buckels, Aparajita Chatterjee, Pang Yuk Cheung, Prasanna Kallingappa, Sree Sreebhavan, Renita M Martis
BackgroundThe lysosomal storage disease cystinosis is caused by mutations in CTNS, encoding a cystine transporter, and in its severest form leads to proximal tubule dysfunction followed by kidney failure. Patients receive the drug-based therapy cyste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1c61537e92aa250d30b4d869ba7b5a3
https://doi.org/10.1101/2021.06.29.450444
https://doi.org/10.1101/2021.06.29.450444
Autor:
Hollywood, Jennifer A., Kallingappa, Prasanna K., Pang Yuk Cheung, Martis, Renita M., Sreebhavan, Sree, 'Atiola, Robert D., Chatterjee, Aparajita, Buckels, Emma J., Matthews, Brya G., Lewis, Paula M., Davidson, Alan J.
Publikováno v:
American Journal of Physiology: Renal Physiology; Aug2022, Vol. 323 Issue 2, pF156-F170, 15p