Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Pang‐hsien Tu"'
Autor:
Ruei‐Yu He, Xiang‐Me Lai, Chia‐Sui Sun, Te‐Shien Kung, Jhu‐Ying Hong, Yu‐Song Jheng, Wei‐Neng Liao, Jen‐Kun Chen, Yung‐Feng Liao, Pang‐Hsien Tu, Joseph Jen‐Tse Huang
Publikováno v:
Advanced Science, Vol 7, Iss 2, Pp n/a-n/a (2020)
Abstract Finding an effective therapeutic regimen is an urgent demand for various neurodegenerative disorders including Huntington's disease (HD). For the difficulties in observing the dynamic aggregation and oligomerization process of mutant Hunting
Externí odkaz:
https://doaj.org/article/ea4bbab767c443acb71235cffdefc1b7
Autor:
Yu‐Sung Cheng, Zih‐ten Chen, Tai‐Yan Liao, Chen Lin, Howard C‐H Shen, Ya‐Han Wang, Chi‐Wei Chang, Ren‐Shyan Liu, Rita P‐Y Chen, Pang‐hsien Tu
Publikováno v:
EMBO Molecular Medicine, Vol 9, Iss 5, Pp 703-715 (2017)
Abstract Alzheimer's disease (AD) is the most common neurodegenerative disease. Imbalance between the production and clearance of amyloid β (Aβ) peptides is considered to be the primary mechanism of AD pathogenesis. This amyloid hypothesis is suppo
Externí odkaz:
https://doaj.org/article/1218aa1f0a354c7fbcfd29f025a528c2
Autor:
Jeng-Fan Lo, Shou-Yen Kao, Ling-Ming Tseng, Pang-Hsien Tu, Pin-I Huang, Yi-Wei Chen, Yueh Chien, Tsann-Long Su, Pen-Yuan Chu, Tsung-Heng Lee, Wen-Liang Lo
Publikováno v:
International Journal of Molecular Sciences, Vol 13, Iss 3, Pp 3277-3290 (2012)
Although surgery or the combination of chemotherapy and radiation are reported to improve the quality of life and reduce symptoms in patients with oral cancer, the prognosis of oral cancer remains generally poor. DNA alkylating agents, such as N-must
Externí odkaz:
https://doaj.org/article/90d734d2e9e447d19a836e97aebc338e
Autor:
Shih-Hwa Chiou, Hsin-Chen Lee, Li-Hsin Chen, Pang-Hsien Tu, Chin-Wen Chi, Pei-Ming Chu, Yi-Jang Lee
Publikováno v:
International Journal of Molecular Sciences, Vol 13, Iss 1, Pp 1209-1224 (2012)
Autophagy is activated by various stresses, including DNA damage, and previous studies of DNA damage-induced autophagy have focused on the response to chemotherapeutic drugs, ionizing radiation, and reactive oxygen species. In this study, we investig
Externí odkaz:
https://doaj.org/article/1b66ebf1e1cf42dab65c213896e0029a
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 13, Iss 8, Pp 704-715 (2011)
The oncogenic property of anaplastic lymphoma kinase (ALK) plays an essential role in the pathogenesis of various cancers and serves as an important therapeutic target. In this study, we identified frequent intragenic loss of heterozygosity and six n
Externí odkaz:
https://doaj.org/article/899ad120d5194633914fa3be73e8e0e5
Autor:
Yi-Chen Huang, Ku-Feng Lin, Ruei-Yu He, Pang-Hsien Tu, Jiri Koubek, Yin-Chih Hsu, Joseph Jen-Tse Huang
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64002 (2013)
The aggregation of TAR DNA-binding protein (TDP-43) has been shown as a hallmark of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) since 2006. While evidence has suggested that mutation or truncation in TDP-43 influe
Externí odkaz:
https://doaj.org/article/71eb4119c5bd438ca180e8fbdab96a04
Autor:
Zih Ten Chen, Ren Shyan Liu, Yu Sung Cheng, Pang-Hsien Tu, Chen Lin, Chi Wei Chang, Ya Han Wang, Rita P.-Y. Chen, Tai Yan Liao, Howard C.-H. Shen
Publikováno v:
EMBO Molecular Medicine
Alzheimer9s disease (AD) is the most common neurodegenerative disease. Imbalance between the production and clearance of amyloid β (Aβ) peptides is considered to be the primary mechanism of AD pathogenesis. This amyloid hypothesis is supported by t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c41cade9251f1718b8728c1bc01ccebb
http://europepmc.org/articles/PMC5412883
http://europepmc.org/articles/PMC5412883
Autor:
Yung‐Feng Liao, Te‐Shien Kung, Yu‐Song Jheng, Pang-Hsien Tu, Chia-Sui Sun, Wei‐Neng Liao, Ruei-Yu He, Jen‐Kun Chen, Joseph Jen-Tse Huang, Jhu‐Ying Hong, Xiang-Me Lai
Publikováno v:
Advanced Science, Vol 7, Iss 2, Pp n/a-n/a (2020)
Advanced Science
Advanced Science
Finding an effective therapeutic regimen is an urgent demand for various neurodegenerative disorders including Huntington's disease (HD). For the difficulties in observing the dynamic aggregation and oligomerization process of mutant Huntingtin (mHtt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0c7641f209762b60986b81669b06378
https://doi.org/10.1002/advs.201901165
https://doi.org/10.1002/advs.201901165
Autor:
Chiung-Tong Chen, Suz Yi Lee, Hsi Wen Yeh, Pang-Hsien Tu, Yuh Charn Lin, Ruey-Bing Yang, Yuh-Shan Jou, De Leung Gu, Jou Ho Shih, Chun Ming Ho, En-Chi Hsu, Ching-Feng Cheng, Chieh-Yu Chang, Chian Feng Chen, Szu Shuo Lee, Ruey-Hwa Chen, Yaw Dong Lang
Publikováno v:
Nature cell biology. 20(4)
Activation of metastatic reprogramming is critical for tumour metastasis. However, more detailed knowledge of the underlying mechanism is needed to enable targeted intervention. Here, we show that paraspeckle component 1 (PSPC1), identified in an abe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4d6c95c31403c80013afaa22ce95a61
https://pubmed.ncbi.nlm.nih.gov/29593320
https://pubmed.ncbi.nlm.nih.gov/29593320
Autor:
Jen-Shiou Lin, Pang-Hsien Tu, Chun-Che Liao, Ya-Shu Chang, An-Ting Liou, Chi-Yung Lin, Chih-Shin Chang, Ya-Yen Yu, Chiaho Shih, Chien-Kuo Lee, Szu-Yao Wu, John T. Kung
Publikováno v:
Journal of Virology. 88:12485-12499
Like poliovirus infection, severe infection with enterovirus 71 (EV71) can cause neuropathology. Unlike poliovirus, EV71 is often associated with hand-foot-and-mouth disease (HFMD). Here we established three mouse models for experimental infection wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b48e11287db08cae98632b76c501ef58
https://doi.org/10.1128/jvi.00692-14
https://doi.org/10.1128/jvi.00692-14