Centipeda minima extracts and the active sesquiterpene lactones have therapeutic efficacy in non-small cell lung cancer by suppressing Skp2/p27 signaling pathway

Autor: Wang, Han-Chen ^{a, b, 1}, Wu, Pei-En ^{a, b, 1}, He, Wen-Da ^{a, b, 1}, Chen, Chu-Ying ^{a, b}, Zheng, Rou-Qiao ^{a, b}, Pang, Yan-Chun ^{a, b}, Wu, Li-Chuan ^d, Cheng, Yong-Xian ^{c, ⁎⁎}, Liu, Yong-Qiang ^{a, b, e, ⁎}

Publikováno v: In Journal of Ethnopharmacology 31 January 2025 340

Identification of arnicolide C as a novel chemosensitizer to suppress mTOR/E2F1/FANCD2 axis in non‐small cell lung cancer.

Autor: Chen, Yu‐Fei, Pang, Yan‐Chun, Wang, Han‐Chen, Wu, Pei‐En, Chen, Zi‐Jie, Huang, Da, Peng, Dong‐Ling, Yan, Yong‐Ming, Liu, Changhui, Wu, Li‐Chuan, Fan, Xiang‐Zhen, Cheng, Yong‐Xian, Liu, Yong‐Qiang

Publikováno v: British Journal of Pharmacology; Apr2024, Vol. 181 Issue 8, p1221-1237, 17p

Centipeda minima extracts and the active sesquiterpene lactones have therapeutic efficacy in non-small cell lung cancer by suppressing Skp2/p27 signaling pathway.

Autor: Wang HC; Research Center of Chinese Herbal Resource Science and Engineering, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China; Key Laboratory of Chinese Medicinal Resource from Lingnan (Guangzhou University of Chinese Medicine), Ministry of Education, Guangzhou, 510006, China., Wu PE; Research Center of Chinese Herbal Resource Science and Engineering, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China; Key Laboratory of Chinese Medicinal Resource from Lingnan (Guangzhou University of Chinese Medicine), Ministry of Education, Guangzhou, 510006, China., He WD; Research Center of Chinese Herbal Resource Science and Engineering, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China; Key Laboratory of Chinese Medicinal Resource from Lingnan (Guangzhou University of Chinese Medicine), Ministry of Education, Guangzhou, 510006, China., Chen CY; Research Center of Chinese Herbal Resource Science and Engineering, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China; Key Laboratory of Chinese Medicinal Resource from Lingnan (Guangzhou University of Chinese Medicine), Ministry of Education, Guangzhou, 510006, China., Zheng RQ; Research Center of Chinese Herbal Resource Science and Engineering, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China; Key Laboratory of Chinese Medicinal Resource from Lingnan (Guangzhou University of Chinese Medicine), Ministry of Education, Guangzhou, 510006, China., Pang YC; Research Center of Chinese Herbal Resource Science and Engineering, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China; Key Laboratory of Chinese Medicinal Resource from Lingnan (Guangzhou University of Chinese Medicine), Ministry of Education, Guangzhou, 510006, China., Wu LC; Guangxi Key Laboratory of Special Biomedicine, School of Medicine, Guangxi University, Nanning, 530004, China., Cheng YX; Guangdong Provincial Key Laboratory of Chinese Medicine Ingredients and Gut Microbiomics, Institute for Inheritance-Based Innovation of Chinese Medicine, Marshall Laboratory of Biomedical Engineering, School of Pharmacy, Shenzhen University Medical School, Shenzhen University, Shenzhen, 518060, China. Electronic address: yxcheng@szu.edu.cn., Liu YQ; Research Center of Chinese Herbal Resource Science and Engineering, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China; Key Laboratory of Chinese Medicinal Resource from Lingnan (Guangzhou University of Chinese Medicine), Ministry of Education, Guangzhou, 510006, China; Dongguan Institute of Guangzhou University of Chinese Medicine, Dongguan, 523808, China. Electronic address: liuyq@gzucm.edu.cn.

Publikováno v: Journal of ethnopharmacology [J Ethnopharmacol] 2024 Dec 23; Vol. 340, pp. 119277. Date of Electronic Publication: 2024 Dec 23.