Zobrazeno 1 - 10
of 1 761
pro vyhledávání: '"Paneth cell"'
Autor:
Jae Hun Shin, Jooyoung Park, Jaechul Lim, Jaekwang Jeong, Ravi K Dinesh, Stephen E Maher, Jeonghyun Kim, Soyeon Park, Jun Young Hong, John Wysolmerski, Jungmin Choi, Alfred LM Bothwell
Publikováno v:
eLife, Vol 13 (2024)
Metastasis is the leading cause of cancer-related mortality. Paneth cells provide stem cell niche factors in homeostatic conditions, but the underlying mechanisms of cancer stem cell niche development are unclear. Here, we report that Dickkopf-2 (DKK
Externí odkaz:
https://doaj.org/article/dffa8146f0424133a38409a5842a0105
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Symbiosis between the host and intestinal microbial communities is essential for human health. Disruption in this symbiosis is linked to gastrointestinal diseases, including inflammatory bowel diseases, as well as extra-gastrointestinal diseases. Unb
Externí odkaz:
https://doaj.org/article/b2ccd5300ae84d819cedf8942bb3f153
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/90ec82c8f1654e83b310980d73d755c0
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-14 (2023)
Abstract Background Mammalian intestinal epithelium constantly undergoes rapid self-renewal and regeneration sustained by intestinal stem cells (ISCs) within crypts. Inducible nitric oxide synthase (iNOS) is an important regulator in tissue homeostas
Externí odkaz:
https://doaj.org/article/066057cc6e29460baa3dd3342af39295
Publikováno v:
Journal of Animal Science and Biotechnology, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract A healthy intestine plays an important role in the growth and development of farm animals. In small intestine, Paneth cells are well known for their regulation of intestinal microbiota and intestinal stem cells (ISCs). Although there has bee
Externí odkaz:
https://doaj.org/article/b366e6fcf4494cab80efd2ae1f92ea76
A stromal lineage maintains crypt structure and villus homeostasis in the intestinal stem cell niche
Autor:
Jinnan Xiang, Jigang Guo, Shaoyang Zhang, Hongguang Wu, Ye-Guang Chen, Junping Wang, Baojie Li, Huijuan Liu
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background The nutrient-absorbing villi of small intestines are renewed and repaired by intestinal stem cells (ISCs), which reside in a well-organized crypt structure. Genetic studies have shown that Wnt molecules secreted by telocytes, Gli1
Externí odkaz:
https://doaj.org/article/f6f8689f796447e3bb47d4a24365f0aa
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
ObjectiveThe current study sought to clarify the role of lysozyme-regulated gut microbiota and explored the potential therapeutic effects of lysozyme on ileum injury induced by severe traumatic brain injury (sTBI) and bacterial pneumonia in vivo and
Externí odkaz:
https://doaj.org/article/b853b2784bf64992b2b04d3694981c52
Autor:
Geoanna M. Bautista, Anjali J. Cera, Rebecca J. Schoenauer, Michele Persiani, Satyan Lakshminrusimha, Praveen Chandrasekharan, Sylvia F Gugino, Mark A. Underwood, Steven J. McElroy
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
IntroductionPaneth cells are critically important to intestinal health, including protecting intestinal stem cells, shaping the intestinal microbiome, and regulating host immunity. Understanding Paneth cell biology in the immature intestine is often
Externí odkaz:
https://doaj.org/article/0eade871870b458a91897c78449cc903
Autor:
Yu Shimizu, Ryodai Yamamura, Yuki Yokoi, Tokiyoshi Ayabe, Shigekazu Ukawa, Koshi Nakamura, Emiko Okada, Akihiro Imae, Takafumi Nakagawa, Akiko Tamakoshi, Kiminori Nakamura
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTSleep is essential for our health. Short sleep is known to increase disease risks via imbalance of intestinal microbiota, dysbiosis. However, mechanisms by which short sleep induces dysbiosis remain unknown. Small intestinal Paneth cell regul
Externí odkaz:
https://doaj.org/article/c1d587c55f914288bff8faa9a0cab49a
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 264, Iss , Pp 115457- (2023)
Deoxynivalenol (DON) is a common toxin in grains and feeds, and DON exposure triggers severe small intestinal injury and inflammation, which harms the health of humans and livestock. DON treatment leads to a decrease in Paneth cells, whereas the role
Externí odkaz:
https://doaj.org/article/db1de6936c2a4b819a11979266e67d77