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Value of large scale expansion of tumor infiltrating lymphocytes in a compartmentalised gas-permeable bag: interests for adoptive immunotherapy

Autor: Khammari Amir, Rodde-Astier Isabelle, Pandolfino Marie-Christine, Bercegeay Sylvain, David Julien, Zuliani Thomas, Coissac Cécile, Delorme Bruno, Saïagh Soraya, Dréno Brigitte

Publikováno v: Journal of Translational Medicine, Vol 9, Iss 1, p 63 (2011)

Abstract Background Adoptive cell therapy (ACT) has emerged as an effective treatment for patients with metastatic melanoma. However, there are several logistical and safety concerns associated with large-scale ex vivo expansion of tumour-specific T

Externí odkaz: https://doaj.org/article/7a94ff3afd3847338be2efe71cf90e52

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Adoptive Transfer of Tumor-Reactive Melan-A-Specific CTL Clones in Melanoma Patients Is Followed by Increased Frequencies of Additional Melan-A-Specific T Cells 1 The Journal of Immunology

Autor: Vignard, Virginie, Lemercier, Brigitte, Lim, Annick, Pandolfino, Marie-Christine, Guilloux, Yannick, Khammari, Amir, Rabu, Catherine, Echasserieau, Klara, Lang, Francois, Gougeon, Marie-Lise, Dréno, Brigitte, Jotereau, Francine, Labarrière, Nathalie

Publikováno v: Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2005, 175 (7), pp.4797-4805. ⟨10.4049/jimmunol.175.7.4797⟩
Journal of Immunology, 2005, 175 (7), pp.4797-4805. ⟨10.4049/jimmunol.175.7.4797⟩

International audience; In this study, we report the adoptive transfer of highly tumor-reactive Melan-A-specific T cell clones to patients with metastatic melanoma, and the follow-up of these injected cells. These clones were generated from HLA-A*020

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4dcdff2550e84be0ce5d74fd87bae122
https://www.hal.inserm.fr/inserm-02482064/document

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