Zobrazeno 1 - 10
of 20 919
pro vyhledávání: '"Pancreatic islets"'
Autor:
Nour Ebrahim, Nikolay Kondratyev, Alexander Artyuhov, Alexei Timofeev, Nadya Gurskaya, Alexey Andrianov, Roman Izrailov, Egor Volchkov, Tatyana Dyuzheva, Elena Kopantseva, Ekaterina Kiseleva, Vera Golimbet, Erdem Dashinimaev
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Background Mesenchymal stromal cells (MSCs) are recognized for their potential in regenerative medicine, attributed to their multipotent differentiation capabilities and immunomodulatory properties. Despite this potential, the classification
Externí odkaz:
https://doaj.org/article/8599933f3e78417799be8b84324609da
Autor:
Szymańczyk Sylwia, Kras Katarzyna, Osiak-Wicha Cezary, Kapica Małgorzata, Puzio Iwona, Antushevich Hanna, Kuwahara Atsukazu, Kato Ikuo, Arciszewski Marcin B.
Publikováno v:
Journal of Veterinary Research, Vol 68, Iss 3, Pp 461-468 (2024)
This study investigated the effects of intragastric administration of apelin-13 on the secretion of critical pancreatic hormones in a cohort of three-week-old Wistar rats. The research aimed to uncover apelin’s modulatory roles in endocrine interac
Externí odkaz:
https://doaj.org/article/2a0371943eec4932ac9e3effe545e993
Autor:
Diana Esparza, Carinna Lima, Sarah Abuelreich, Ima Ghaeli, Jinhee Hwang, Eunjin Oh, Ayelet Lenz, Angel Gu, Nan Jiang, Fouad Kandeel, Debbie C. Thurmond, Tijana Jovanovic-Talisman
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionDouble C2-like domain beta (DOC2B) is a vesicle priming protein critical for glucose-stimulated insulin secretion in β-cells. Individuals with type 1 diabetes (T1D) have lower levels of DOC2B in their residual functional β-cell mass and
Externí odkaz:
https://doaj.org/article/49be9d7536124d169961b687cb510217
Publikováno v:
Current Internal Medicine Research and Practice Surabaya Journal, Vol 5, Iss 2 (2024)
Introduction: It is necessary to develop alternative antidiabetic therapies that are safer and more affordable to overcome the high prevalence of diabetes mellitus in Indonesia. Ajwa dates (Phoenix dactylifera) have a high flavonoid content; hence, t
Externí odkaz:
https://doaj.org/article/2bdd738bbe1d4cb5a8816571a40d125e
Autor:
Sarah Grimus, Victoria Sarangova, Petra B. Welzel, Barbara Ludwig, Jochen Seissler, Elisabeth Kemter, Eckhard Wolf, Asghar Ali
Publikováno v:
Advanced Science, Vol 11, Iss 31, Pp n/a-n/a (2024)
Abstract Type 1 diabetes mellitus (T1DM) is characterized by absolute insulin deficiency primarily due to autoimmune destruction of pancreatic β‐cells. The prevailing treatment for T1DM involves daily subcutaneous insulin injections, but a substan
Externí odkaz:
https://doaj.org/article/81d8d2b5304a4da893a6f63d70c7a318
Autor:
Hamed Dabiri, Mahdi Habibi-Anbouhi, Vahab Ziaei, Zahra Moghadasi, Majid Sadeghizadeh, Ensiyeh Hajizadeh-Saffar
Publikováno v:
Cell Journal, Vol 26, Iss 1, Pp 51-61 (2024)
Objective: Type 1 diabetes (T1Ds) is an autoimmune disease in which the immune system invades and destroysinsulin-producing cells. Nevertheless, at the time of diagnosis, about 30-40% of pancreatic beta cells are healthy andcapable of producing insul
Externí odkaz:
https://doaj.org/article/92b2739b94c34fefa81181a2be361723
Autor:
Intisar Al Alawi, Ehab Mohammed, Fatma Al Rahbi, AbdelMasieh Metry, Suad Hannawi, Issa Al Salmi
Publikováno v:
Oman Medical Journal, Vol 39, Iss 3, Pp e636-e636 (2024)
Autosomal dominant polycystic kidney disease (ADPKD) is a common inherited condition characterized by the growth of multiple bilateral cysts in the kidneys. We describe the case of a 35-year-old male with combined ADPKD and type 1 diabetes mellitus w
Externí odkaz:
https://doaj.org/article/bf1c9462bca2443b9d71535ff760ae64
Revisiting pancreatic islet isolation in murine models: A practical and effective technical protocol
Autor:
Aline Fernandes‐da‐Silva, Rosiane Aparecida Miranda, Patricia Cristina Lisboa, Vanessa Souza‐Mello
Publikováno v:
Physiological Reports, Vol 12, Iss 9, Pp n/a-n/a (2024)
Abstract The endocrine pancreas is composed of clusters of cell groups called pancreatic islets. These cells are responsible for the synthesis and secretion of hormones crucial for glycemic homeostasis, such as insulin and glucagon. Therefore, these
Externí odkaz:
https://doaj.org/article/2ee26d4838544ff19a5c1b2126269db4
Autor:
Debora S. Rocha, Antonio C. Manucci, Alexandre Bruni-Cardoso, Alicia J. Kowaltowski, Eloisa A. Vilas-Boas
Publikováno v:
Molecular Metabolism, Vol 83, Iss , Pp 101922- (2024)
Objective: Evaluation of mitochondrial oxygen consumption and ATP production is important to investigate pancreatic islet pathophysiology. Most studies use cell lines due to difficulties in measuring primary islet respiration, which requires specific
Externí odkaz:
https://doaj.org/article/1ed00cd0117949418d4b530eb6c90353