Zobrazeno 1 - 10
of 21 802
pro vyhledávání: '"Pancreatic islets"'
Autor:
Hamed Dabiri, Mahdi Habibi-Anbouhi, Vahab Ziaei, Zahra Moghadasi, Majid Sadeghizadeh, Ensiyeh Hajizadeh-Saffar
Publikováno v:
Cell Journal, Vol 26, Iss 1, Pp 51-61 (2024)
Objective: Type 1 diabetes (T1Ds) is an autoimmune disease in which the immune system invades and destroysinsulin-producing cells. Nevertheless, at the time of diagnosis, about 30-40% of pancreatic beta cells are healthy andcapable of producing insul
Externí odkaz:
https://doaj.org/article/92b2739b94c34fefa81181a2be361723
Akademický článek
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Akademický článek
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Autor:
Intisar Al Alawi, Ehab Mohammed, Fatma Al Rahbi, AbdelMasieh Metry, Suad Hannawi, Issa Al Salmi
Publikováno v:
Oman Medical Journal, Vol 39, Iss 3, Pp e636-e636 (2024)
Autosomal dominant polycystic kidney disease (ADPKD) is a common inherited condition characterized by the growth of multiple bilateral cysts in the kidneys. We describe the case of a 35-year-old male with combined ADPKD and type 1 diabetes mellitus w
Externí odkaz:
https://doaj.org/article/bf1c9462bca2443b9d71535ff760ae64
Revisiting pancreatic islet isolation in murine models: A practical and effective technical protocol
Autor:
Aline Fernandes‐da‐Silva, Rosiane Aparecida Miranda, Patricia Cristina Lisboa, Vanessa Souza‐Mello
Publikováno v:
Physiological Reports, Vol 12, Iss 9, Pp n/a-n/a (2024)
Abstract The endocrine pancreas is composed of clusters of cell groups called pancreatic islets. These cells are responsible for the synthesis and secretion of hormones crucial for glycemic homeostasis, such as insulin and glucagon. Therefore, these
Externí odkaz:
https://doaj.org/article/2ee26d4838544ff19a5c1b2126269db4
Autor:
Debora S. Rocha, Antonio C. Manucci, Alexandre Bruni-Cardoso, Alicia J. Kowaltowski, Eloisa A. Vilas-Boas
Publikováno v:
Molecular Metabolism, Vol 83, Iss , Pp 101922- (2024)
Objective: Evaluation of mitochondrial oxygen consumption and ATP production is important to investigate pancreatic islet pathophysiology. Most studies use cell lines due to difficulties in measuring primary islet respiration, which requires specific
Externí odkaz:
https://doaj.org/article/1ed00cd0117949418d4b530eb6c90353
Publikováno v:
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, Vol 16, Iss 3, Pp 244-248 (2023)
Large-scale epidemiological studies have shown that cardiac pathology and progressive atherosclerosis in patients with diabetes mellitus occurred already at the stage of prediabetes. Obesity and insulin resistance affect cardiometabolic health due to
Externí odkaz:
https://doaj.org/article/5e953939b37340269dae25722ae75b21
Publikováno v:
SLAS Discovery, Vol 28, Iss 7, Pp 316-324 (2023)
Diabetes poses a global health crisis affecting individuals across age groups and backgrounds, with a prevalence estimate of 700 million people worldwide by 2045. Current therapeutic strategies primarily rely on insulin therapy or hypoglycemic agents
Externí odkaz:
https://doaj.org/article/aa92df8419fd44b28a2d2030738a26df
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-22 (2023)
Abstract Background Our recent studies have demonstrated the crucial involvement of FOXA2 in the development of human pancreas. Reduction of FOXA2 expression during the differentiation of induced pluripotent stem cells (iPSCs) into pancreatic islets
Externí odkaz:
https://doaj.org/article/1c67c65a3a854c079aca85b1e4c6d83a