Zobrazeno 1 - 10
of 1 060
pro vyhledávání: '"Pancreatic islet transplantation"'
Publikováno v:
Radiology and Oncology, Vol 57, Iss 1, Pp 51-58 (2023)
Pancreatic islet transplantation via infusion through the portal vein, has become an established clinical treatment for patients with type 1 diabetes. Because the engraftment efficiency is low, new approaches for pancreatic islets implantation are so
Externí odkaz:
https://doaj.org/article/018939464bef457a920400a6e97cfb67
Autor:
Marta Wolanin, Bartłomiej Stachyra, Cezary Stawikowski, Bartłomiej Zielonka, Aleksandra Osińska, Izabela Wolanin, Karolina Madej, Barbara Dengler, Ilona Kowalczyk, Paulina Krawiec
Publikováno v:
Journal of Education, Health and Sport, Vol 32, Iss 1 (2023)
Introduction: Type 1 diabetes is a common and debilitating disease that requires regular glycemic control to prevent potentially fatal hypoglycemia. Objective: The aim of this study is to demonstrate the purpose, process, and consequences of p
Externí odkaz:
https://doaj.org/article/ab0f54a7f4534d3baa32ec7345a54417
Autor:
George J. Dugbartey
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Pancreatic islet transplantation is a minimally invasive procedure to replace β-cells in a subset of patients with autoimmune type 1 diabetic mellitus, who are extremely sensitive to insulin and lack counter-regulatory measures, and thereby increasi
Externí odkaz:
https://doaj.org/article/7d16a296eaf444a1b82aeb32b5d71259
Autor:
Vincent Nuernberger, Sharif Mortoga, Christoph Metzendorf, Christian Burkert, Katrina Ehricke, Elisa Knuth, Jenny Zimmer, Stephan Singer, Neetika Nath, Majedul Karim, Mohd Yasser, Diego F. Calvisi, Frank Dombrowski, Silvia Ribback
Publikováno v:
Cells, Vol 10, Iss 10, p 2787 (2021)
Objective: In the rat, the pancreatic islet transplantation model is an established method to induce hepatocellular carcinomas (HCC), due to insulin-mediated metabolic and molecular alterations like increased glycolysis and de novo lipogenesis and th
Externí odkaz:
https://doaj.org/article/9a3570447dce481f80290783ce224139
Autor:
Mieke Baan, Steven J. Sacotte, Joseph T. Blumer, Jee Young Han, Heidi M. Umhoefer, Lucille E. Anzia, Rashaun A. Williams, Danielle A. Fontaine, Arnaldo H. de Souza, Carly R. Kibbe, Dawn Belt Davis, Jacob T. Bartosiak, Hung Tae Kim
Publikováno v:
Transl Res
Loss of functional pancreatic β-cell mass and increased β-cell apoptosis are fundamental to the pathophysiology of type 1 and type 2 diabetes. Pancreatic islet transplantation has the potential to cure type 1 diabetes but is often ineffective due t
Autor:
Wallace, Eimear J.
Type 1 diabetes mellitus is an autoimmune condition whereby β-cells are destroyed by the immune system causing the lack/absence of insulin production and resultant hyperglycaemia. Pancreatic islet transplantation is considered a potential cure for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1513::db42f2f558464377bb808f099bcb4179
http://hdl.handle.net/10379/17687
http://hdl.handle.net/10379/17687
Autor:
Maffi P., Lundgren T., Tufveson G., Rafael E., Shaw J. A. M., Liew A., Saudek F., Witkowski P., Golab K., Bertuzzi F., Gustafsson B., Daffonchio L., Ruffini P. A., Piemonti L., Nano R., Mercalli A., Lampasona V., Magistretti P., Sordi V., Antonio S., Antonioli B., Galuzzi M., Tosca M. C., De Carlis L., Colussi G., Korsgren O., Pollard H.
Publikováno v:
Diabetes Care
OBJECTIVE Reparixin is an inhibitor of CXCR1/2 chemokine receptor shown to be an effective anti-inflammatory adjuvant in a pilot clinical trial in allotransplant recipients. RESEARCH DESIGN AND METHODS A phase 3, multicenter, randomized, double-blind
Autor:
Valérie B. Schini-Kerth, Guillaume Kreutter, Ali El Habhab, Florence Toti, Lamia Amoura, Fatiha Zobairi, Laurence Kessler, Noura Sbat, Mohamad Kassem, Malak Abbas, Philippe Baltzinger
Publikováno v:
Transplantation Proceedings. 53:1736-1743
Ischemia-driven islet isolation procedure is one of the limiting causes of pancreatic islet transplantation. Ischemia-reperfusion process is associated with endothelium dysfunction and the release of pro-senescent microvesicles. We investigated wheth
Autor:
Michelle B. Paget, R. Downing, Hilary E. Murray, Khalid M Qureshi, Ali Zafar, Clifford J. Bailey
Publikováno v:
Journal of Tissue Engineering and Regenerative Medicine. 15:599-611
Pancreatic islet cell transplantation has proven efficacy as a treatment for type 1 diabetes mellitus, chiefly in individuals who are refractory to conventional insulin replacement therapy. At present its clinical use is restricted, firstly by the li
Publikováno v:
Current Stem Cell Reports. 7:49-71
Although the current treatment option of exogenous insulin administration for type 1 diabetes mellitus (T1DM) corrects hyperglycemia, it has its own limitations and complications in long-term use. Thus, alternative approaches such as immune therapies