Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Pancreas/embryology"'
Autor:
Perez-Frances, Marta, van Gurp, Léon, Abate, Maria Valentina, Cigliola, Valentina, Furuyama, Kenichiro, Bru-Tari, Eva, Oropeza, Daniel, Carreaux, Taïna, Fujitani, Yoshio, Thorel, Fabrizio, Herrera, Pedro L.
Publikováno v:
Nature Communications, Vol. 12, No 1 (2021) P. 4458
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
The cellular identity of pancreatic polypeptide (Ppy)-expressing γ-cells, one of the rarest pancreatic islet cell-type, remains elusive. Within islets, glucagon and somatostatin, released respectively from α- and δ-cells, modulate the secretion of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0e274366e2ce886b3c58fa685badcbbd
https://archive-ouverte.unige.ch/unige:153672
https://archive-ouverte.unige.ch/unige:153672
Autor:
Hugo Marcelino, Renata Bordeira-Carriço, Solangel Rivero-Gil, José Bessa, Silvia Naranjo, Ana Gali-Macedo, Joana Teixeira, Mafalda Galhardo, João Amorim, Joana Marques
Publikováno v:
Cell Reports
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
Summary The notochord is an evolutionary novelty in vertebrates that functions as an important signaling center during development. Notochord ablation in chicken has demonstrated that it is crucial for pancreas development; however, the molecular mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc569be2d6a1ae87e3d8b4813f991da2
https://hdl.handle.net/10216/143488
https://hdl.handle.net/10216/143488
Autor:
Yung Hae Kim, Jacques-Antoine Haefliger, Chai An Mao, Anne Grapin-Botton, David Martin, Dror Sever
Publikováno v:
Developmental Biology, vol. 405, no. 2, pp. 316-327
Developmental biology
Developmental biology
To contribute to devise successful beta-cell differentiation strategies for the cure of Type 1 diabetes we sought to uncover barriers that restrict endocrine fate acquisition by studying the role of the transcriptional repressor REST in the developin
Publikováno v:
Mechanisms of Development, Vol. 121, No 1 (2004) pp. 3-14
Expression of nestin has been suggested to be a characteristic of pancreatic islet stem cells. To determine whether nestin is indeed expressed in such putative cells during embryonic development, or in the adult pancreas after injury, we performed a
Autor:
Liliana Kockel, Otto Hagenbüchle, Peter K. Wellauer, Alexandra Delacour, Alessandra Strom, Pedro Luis Herrera, Virginie Nepote
Publikováno v:
Genesis, Vol. 44, No 6 (2006) pp. 287-296
Mice bearing a Cre-encoding transgene driven by a compound [SV40 small t antigen/mousealpha-amylase-2] promoter expressed the recombinase at early developmental stages broadly in the embryonic endoderm before the pancreas and lungs begin to outgrow,
Autor:
Claude Bachmann, Hugues Henry, Anne-Marie Villard, Oliver Speer, Olivier Braissant, Theo Wallimann
Publikováno v:
BMC Developmental Biology, vol. 5, pp. 9
BMC Developmental Biology, Vol 5, Iss 1, p 9 (2005)
BMC Developmental Biology, 5
BMC Developmental Biology
BMC Developmental Biology, Vol 5, Iss 1, p 9 (2005)
BMC Developmental Biology, 5
BMC Developmental Biology
Background Creatine (Cr) is synthesized by a two-step mechanism involving arginine:glycine amidinotransferase (AGAT) and guanidinoacetate methyltransferase (GAMT), and is taken up by cells through a specific Cr transporter, CT1. Recently, genetic def
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb5438bdc8c971108428204d883f9af4
https://serval.unil.ch/notice/serval:BIB_3499339AF34C
https://serval.unil.ch/notice/serval:BIB_3499339AF34C
Autor:
Beate Ritz-Laser, Jacques Philippe, Thierry Brun, Aline Mamin, Valerie M. Schwitzgebel, Isabelle Avril
Publikováno v:
Molecular Endocrinology, Vol. 19, No 3 (2005) pp. 759-70
Gene inactivation studies have shown that members of the Gata family of transcription factors are critical for endoderm development throughout evolution. We show here that Gata-4 and/or Gata-6 are not only expressed in the adult exocrine pancreas but
Publikováno v:
Developmental Biology, Vol. 278, No 2 (2005) pp. 484-495
The differentiation of insulin-producing beta-cells has been investigated in great detail; however, little is known about the factors that delineate the second-most abundant endocrine lineage, the glucagon-producing alpha-cell. Here we utilize a nove
Autor:
R. Scharfmann, J. P. H. Shield
It is now clear that abnormal pancreas development can give rise to specific forms of diabetes. Thus, the study of human and animal pancreatic developmental biology, one of the main focuses of the current volume of'Endocrine Development', is crucial
Autor:
Francesca Sanvito, Roberto Montesano, Jean-Dominique Vassalli, Pedro Luis Herrera, Joachim Huarte, Anthony Nichols, Lelio Orci
Publikováno v:
Development, Vol. 120, No 12 (1994) pp. 3451-3462
Europe PubMed Central
Europe PubMed Central
Pancreatic rudiments from E12.5 mouse embryos undergo extensive development and differentiation when cultured in three-dimensional gels of extracellular matrix proteins for up to 12 days. Whereas collagen gels promote the formation of numerous exocri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e6ba2bb396a034e24df142d5bf336b4
https://archive-ouverte.unige.ch/unige:9014
https://archive-ouverte.unige.ch/unige:9014