Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Panayotis Catsoulacos"'
Autor:
Dionysios Mourelatos, A. Paradelis, A. Anastasiou, L. Boutis, Athanasios A. Papageorgiou, E. Mylonaki, Panayotis Catsoulacos
Publikováno v:
Mutation Research Letters. 346:129-133
The effect of homo-azasteroidal esters of benzoic acid mustard isomers and the 4-methyl derivatives, which have steroidal lactams as a biological basis, on cytogenetic damage was studied. Twenty compounds were comparatively studied, on a molar basis,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::427996c8b983a495d1509cbb5dab6e7e
https://doi.org/10.1016/0165-7992(95)90044-6
https://doi.org/10.1016/0165-7992(95)90044-6
Publikováno v:
Journal of Heterocyclic Chemistry. 31:367-374
The N, N-bis(2-chloroethyl)aminobenzoate isomers and the 4-methyl-3-N, N-bis(2-chloro-ethyl)aminobenzoate of 3β-hydroxy-13α-amino-13,17-seco-5α-androstan-17-oic-13,17-lactam, 3α-hydroxy-13α-amino-13,17-seco-5α-androstan-17-oic-13,17-lactam, 3α
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aeed44f45c43b52aeafc826055434116
https://doi.org/10.1002/jhet.5570310219
https://doi.org/10.1002/jhet.5570310219
Autor:
D. Catsoulacos, Panayotis Catsoulacos
Publikováno v:
Journal of Heterocyclic Chemistry. 30:1-10
The Beckmann rearrangement of steroidal oximes is reported. Different methods of esterification of homo-aza-steroids with carboxylic derivatives of N,N-bis(2-chloroethyl)aniline are reported. The lipophilic nature of the steroidal hormones is the rea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62ec6d30e8a809d7c0b78c94d520acfc
https://doi.org/10.1002/jhet.5570300101
https://doi.org/10.1002/jhet.5570300101
Autor:
D. Catsoulacos, Panayotis Catsoulacos
Publikováno v:
Journal of Heterocyclic Chemistry. 29:675-682
This review article comprises tetracyclic rigid analogues of phenothiazine and dibenzothiazepine derivatives. In order to discover new useful drugs, the side chain of the heterocyclic nucleus is incorporated into a ring forming tetracyclic compounds.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb90ee9646aa1cd36fb97851615f5846
https://doi.org/10.1002/jhet.5570290401
https://doi.org/10.1002/jhet.5570290401
Publikováno v:
Teratogenesis, Carcinogenesis, and Mutagenesis. 10:321-331
Enhanced cytogenetic damage by the homo-aza-steroidal ester of p-bis (2-chloroethyl)-aminophenylacetic acid (ASE) was observed when human lymphocytes in vitro or Ehrlich ascites tumor (EAT) cells in vivo were exposed to nontoxic concentrations of 3-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4a6420dd9c041120146e9ee8306cc47
https://doi.org/10.1002/tcm.1770100405
https://doi.org/10.1002/tcm.1770100405
Publikováno v:
Journal of Heterocyclic Chemistry. 32:1063-1065
New estrone-lactam esters, 17α-aza-D-homo-Δ1,3,5(10)-estratrien-3-ol-17-one-N,N-bis(2-chloroethyl)-aminocinnamic isomers and p-N,N-bis(2-chloroethyl)aminophenylbutyrate have been synthesized and tested in P388 leukemia in vivo and P388 and L1210 le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92553db1e6e50b53e474ab1028a49c1f
https://doi.org/10.1002/jhet.5570320365
https://doi.org/10.1002/jhet.5570320365
Publikováno v:
Journal of Heterocyclic Chemistry. 27:1997-1999
Beckmann rearrangement of 3α- and 3β-acetamido-5α-androstan-17-one oximes gives homo-aza compounds and the corresponding “second order” Beckmann cleavage ω-cyanoolefin. The mixture of the compounds produced, was separated by column chromatogr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70706b9000f3d2ead6a58a5945ada7fc
https://doi.org/10.1002/jhet.5570270728
https://doi.org/10.1002/jhet.5570270728
Autor:
E. Mioglou, Elizabeth Margarity, Athanasios A. Papageorgiou, Panayotis Catsoulacos, Dionysis Mourelatos
Publikováno v:
Oncology. 51(1)
The modified steroidal alkylating agent, 17 beta-hydroxy-3-aza-A-homo-4 alpha-androsten-4-one-p-bis(2-chloroethyl)aminophenoxyacetate++ + has been tested against L1210 and P388 leukemias, and Lewis lung cancer, on DNA synthesis of EAT, L1210, P388, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96c3686e59185874e276bb0fdac12ce7
https://pubmed.ncbi.nlm.nih.gov/8265107
https://pubmed.ncbi.nlm.nih.gov/8265107
Publikováno v:
Mutation research. 290(2)
The clastogenic activity of the antineoplastic alkylating agent 3 beta-hydroxy-13 alpha-amino-13,17-seco-5 alpha-androstan-17-oic-13,17-lactam- p-bis (2-chloroethyl) aminophenoxy acetic acid (NSC 294859) and its congeners was studied in human lymphoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc990f3806df2055ad99dc8946e7ce0b
https://pubmed.ncbi.nlm.nih.gov/7694112
https://pubmed.ncbi.nlm.nih.gov/7694112
Autor:
Panayotis Catsoulacos, N. Demopoulos, K. Psaraki, A. Papageorgiou, E. Margariti, Ch. Camoutsis
Publikováno v:
Journal of pharmaceutical sciences. 82(2)
Four steroidal lactams of the A- and D-rings were used for the esterification in the C-3 or C-17 positions, respectively, of their nuclei with the W,N-bis(2-chloroethyl)aminocinnamic acid isomers. The con-densation reaction of the hydroxylic group of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e92f5f5e11bc055979d30b7c9fad46f0
https://pubmed.ncbi.nlm.nih.gov/8445536
https://pubmed.ncbi.nlm.nih.gov/8445536