Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Panagiotis Mistriotis"'
Autor:
Tosin Akinsipe, Rania Mohamedelhassan, Ayuba Akinpelu, Satyanarayana R. Pondugula, Panagiotis Mistriotis, L. Adriana Avila, Amol Suryawanshi
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The breast cancer tumor microenvironment (TME) is dynamic, with various immune and non-immune cells interacting to regulate tumor progression and anti-tumor immunity. It is now evident that the cells within the TME significantly contribute to breast
Externí odkaz:
https://doaj.org/article/5b9000da7d0d456998136d96c387be86
Downregulation of YAP Activity Restricts P53 Hyperactivation to Promote Cell Survival in Confinement
Autor:
Farnaz Hemmati, Ayuba Akinpelu, Jiyeon Song, Farshad Amiri, Anya McDaniel, Collins McMurray, Alexandros Afthinos, Stelios T. Andreadis, Andrew V. Aitken, Vinicia C. Biancardi, Sharon Gerecht, Panagiotis Mistriotis
Publikováno v:
Advanced Science, Vol 10, Iss 23, Pp n/a-n/a (2023)
Abstract Cell migration through confining three dimensional (3D) topographies can lead to loss of nuclear envelope integrity, DNA damage, and genomic instability. Despite these detrimental phenomena, cells transiently exposed to confinement do not us
Externí odkaz:
https://doaj.org/article/0ffb15d0004f4eed9ae794c90274936d
Autor:
Yuqi Zhang, Yizeng Li, Keyata N. Thompson, Konstantin Stoletov, Qinling Yuan, Kaustav Bera, Se Jong Lee, Runchen Zhao, Alexander Kiepas, Yao Wang, Panagiotis Mistriotis, Selma A. Serra, John D. Lewis, Miguel A. Valverde, Stuart S. Martin, Sean X. Sun, Konstantinos Konstantopoulos
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Cell migration regulates diverse (patho)physiological processes, including cancer metastasis. Here the authors show that the chloride ion channel SWELL1 and the ion exchanger NHE1 are preferentially enriched at the trailing and leading edges, respect
Externí odkaz:
https://doaj.org/article/e0d59226dc564a198172e55e93cfb59f
Autor:
Mohammad Ikbal Choudhury, Yizeng Li, Panagiotis Mistriotis, Ana Carina N. Vasconcelos, Eryn E. Dixon, Jing Yang, Morgan Benson, Debonil Maity, Rebecca Walker, Leigha Martin, Fatima Koroma, Feng Qian, Konstantinos Konstantopoulos, Owen M. Woodward, Sean X. Sun
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
How mechanical forces drive fluid transport in the kidney remains unclear. Here, the authors use a microfluidic platform to show that kidney epithelial cells generate hydraulic pressure gradients across the epithelium, and that the fluid flux is from
Externí odkaz:
https://doaj.org/article/b58fd862a1154805bc1deba371303c2a
Autor:
Suman Mazumder, Taraswi Mitra Ghosh, Ujjal K. Mukherjee, Sayak Chakravarti, Farshad Amiri, Razan S. Waliagha, Farnaz Hemmati, Panagiotis Mistriotis, Salsabil Ahmed, Isra Elhussin, Ahmad-Bin Salam, Windy Dean-Colomb, Clayton Yates, Robert D. Arnold, Amit K. Mitra
Publikováno v:
Cancers, Vol 14, Iss 23, p 6009 (2022)
Metastatic prostate cancer/PCa is the second leading cause of cancer deaths in US men. Most early-stage PCa are dependent on overexpression of the androgen receptor (AR) and, therefore, androgen deprivation therapies/ADT-sensitive. However, eventual
Externí odkaz:
https://doaj.org/article/fd4ec0821ca04016bc4e837be10c4ac0
Autor:
Rajappa S. Kenchappa, Panagiotis Mistriotis, Emily Wisniewski, Santanu Bhattacharya, Tanmay Kulkarni, Rita West, Amanda Luu, Meghan Conlon, Ernest Heimsath, James F. Crish, Hannah S. Picariello, Athanassios Dovas, Natanael Zarco, Montserrat Lara-Velazquez, Alfredo Quiñones-Hinojosa, John A. Hammer, Debrabrata Mukhopadhyay, Richard E. Cheney, Konstantinos Konstantopoulos, Peter Canoll, Steven S. Rosenfeld
Publikováno v:
iScience, Vol 23, Iss 12, Pp 101802- (2020)
Summary: Invasion and proliferation are defining phenotypes of cancer, and in glioblastoma blocking one stimulates the other, implying that effective therapy must inhibit both, ideally through a single target that is also dispensable for normal tissu
Externí odkaz:
https://doaj.org/article/f2e6aa1145ad433d8b3c718e8b0b6bf0
Autor:
Dipali Sharma, Cynthia L. Sears, Kathleen L. Gabrielson, Konstantinos Konstantopoulos, C. Conover Talbot, Haiping Hao, Panagiotis Mistriotis, Christina Hum, Arumugam Nagalingam, Nethaji Muniraj, Guannan Wang, Sumit Siddharth, Shaoguang Wu, Sheetal Parida
The existence of distinct breast microbiota has been recently established, but their biological impact in breast cancer remains elusive. Focusing on the shift in microbial community composition in diseased breast compared with normal breast, we ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::182cd1108590ba3794fdd495028e2a62
https://doi.org/10.1158/2159-8290.c.6549004.v1
https://doi.org/10.1158/2159-8290.c.6549004.v1
Autor:
Dipali Sharma, Cynthia L. Sears, Kathleen L. Gabrielson, Konstantinos Konstantopoulos, C. Conover Talbot, Haiping Hao, Panagiotis Mistriotis, Christina Hum, Arumugam Nagalingam, Nethaji Muniraj, Guannan Wang, Sumit Siddharth, Shaoguang Wu, Sheetal Parida
Supplementary Figures and Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d946c2684f0b166d598de3f942432eb
https://doi.org/10.1158/2159-8290.22539160
https://doi.org/10.1158/2159-8290.22539160
Autor:
Konstantinos Konstantopoulos, Lei Zheng, Jake M. Bieber, Robert A. Law, Soontorn Tuntithavornwat, Panagiotis Mistriotis, Daniel J. Shea, Bin Sheng Wong
PODXL knockdown impairs 2D random migration of metastatic pancreatic cancer cells. Representative scramble control (left) and PODXL-KD (right) SW1990 cells migrating on collagen I-coated glass coverslips. Scale bar represents 50 µm. Related to Fig.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50be4d4539af9b3ed28217f91339bc74
https://doi.org/10.1158/0008-5472.22421237.v1
https://doi.org/10.1158/0008-5472.22421237.v1
Autor:
Konstantinos Konstantopoulos, Lei Zheng, Jake M. Bieber, Robert A. Law, Soontorn Tuntithavornwat, Panagiotis Mistriotis, Daniel J. Shea, Bin Sheng Wong
Contains Supplementary Figures, Supplementary Figure Legends, Supplementary Video Legends, Supplementary Table and Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22badf1cb6c578e8d7b61f87cced0b86
https://doi.org/10.1158/0008-5472.22421240.v1
https://doi.org/10.1158/0008-5472.22421240.v1