Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Panagiotis Kratimenos"'
Autor:
Ioannis Koutroulis, Panagiotis Kratimenos, Claire Hoptay, Wade N. O’Brien, Georgios Sanidas, Chad Byrd, Maria Triantafyllou, Evan Goldstein, Beata Jablonska, Manish Bharadwaj, Vittorio Gallo, Robert Freishtat
Publikováno v:
iScience, Vol 27, Iss 8, Pp 110573- (2024)
Summary: Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection that results in high mortality and long-term sequela. The central nervous system (CNS) is susceptible to injury from infectious processes, whi
Externí odkaz:
https://doaj.org/article/a075182050e049bfa0225adabbd8bc97
Autor:
Beata Jablonska, Katrina L. Adams, Panagiotis Kratimenos, Zhen Li, Emma Strickland, Tarik F. Haydar, Katharina Kusch, Klaus-Armin Nave, Vittorio Gallo
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Neonatal hypoxia leads to white matter hypomyelination due to delayed oligodendrocyte maturation. The authors identify Sirt2 as a crucial regulator of oligodendrocyte differentiation during normal white matter development and in response to hypoxia.
Externí odkaz:
https://doaj.org/article/c167f6696dc7460d99faafb94bd5a660
Autor:
Panagiotis Kratimenos, Abhya Vij, Robinson Vidva, Ioannis Koutroulis, Maria Delivoria-Papadopoulos, Vittorio Gallo, Aaron Sathyanesan
Publikováno v:
Journal of Neurodevelopmental Disorders, Vol 14, Iss 1, Pp 1-16 (2022)
Abstract Background Neonatal hypoxic brain injury is a major cause of intellectual and developmental disability. Hypoxia causes neuronal dysfunction and death in the developing cerebral cortex due to excitotoxic Ca2+-influx. In the translational pigl
Externí odkaz:
https://doaj.org/article/bfbd70b4100442eca832757bd4e54d0b
Autor:
Panagiotis Christidis, Abhya Vij, Stamatios Petousis, Javid Ghaemmaghami, Bhairav V. Shah, Ioannis Koutroulis, Panagiotis Kratimenos
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
BackgroundHypoxic-ischemic encephalopathy (HIE) is a major cause of neonatal morbidity and mortality worldwide. While the application of therapeutic hypothermia has improved neurodevelopmental outcomes for some survivors of HIE, this lone treatment o
Externí odkaz:
https://doaj.org/article/9b5722c5bb5f440cb916002f75ae8a20
Autor:
Panagiotis Kratimenos, Evan Z. Goldstein, Ioannis Koutroulis, Susan Knoblach, Beata Jablonska, Payal Banerjee, Shadi N. Malaeb, Surajit Bhattacharya, M. Isabel Almira-Suarez, Vittorio Gallo, Maria Delivoria-Papadopoulos
Publikováno v:
iScience, Vol 23, Iss 12, Pp 101766- (2020)
Summary: Acute hypoxia (HX) causes extensive cellular damage in the developing human cerebral cortex. We found increased expression of activated-EGFR in affected cortical areas of neonates with HX and investigated its functional role in the piglet, w
Externí odkaz:
https://doaj.org/article/47be4abbcf6445059095a33d92ed3cc3
Autor:
Chariton Moschopoulos, Panagiotis Kratimenos, Ioannis Koutroulis, Bhairav V. Shah, Anja Mowes, Vineet Bhandari
Publikováno v:
Mediators of Inflammation, Vol 2018 (2018)
This state-of-the-art review article aims to highlight the most recent evidence about the therapeutic options of surgical necrotizing enterocolitis, focusing on the molecular basis of the gut-brain axis in relevance to the neurodevelopmental outcomes
Externí odkaz:
https://doaj.org/article/e892fdc7720941e0ac45462b9b4eca24
Autor:
Spyridon A. Karageorgos, Panagiotis Kratimenos, Ashley Landicho, Joshua Haratz, Louis Argentine, Amit Jain, Andrew D. McInnes, Margaret Fisher, Ioannis Koutroulis
Publikováno v:
Children, Vol 5, Iss 10, p 139 (2018)
Hypotonic solutions have been used in pediatrics for maintenance of intravenous (IV) hydration. However, recent randomized control trials and cohort studies have raised significant concerns for association with hospital-acquired hyponatremia (HAH). T
Externí odkaz:
https://doaj.org/article/92b122c55c7e468f8bb74d373a3e8a18
Autor:
George Spyropoulos, Panagiotis Kratimenos, Andrew D. Mcinnes, Richard J. DeGroote, Ioannis Koutroulis
Publikováno v:
Case Reports in Pediatrics, Vol 2014 (2014)
A previously healthy, white 12-year-old girl presented with diffuse body aches and poor perfusion. She developed severe respiratory failure and marked rhabdomyolysis and was mechanically ventilated. Although her CPK peaked at 500,000 IU/L, her renal
Externí odkaz:
https://doaj.org/article/c53d27ca0cfa40dbaa67c6fe7e0931c7
Autor:
Panagiotis Kratimenos, Ioannis Koutroulis, Dante Marconi, Jennifer Ding, Christos Plakas, Margaret Fisher
Publikováno v:
Case Reports in Pediatrics, Vol 2014 (2014)
Background. The prepatellar bursa can become inflamed owing to repeated trauma. Prepatellar bursitis is extremely rare in children. Methods. We report the case of an 8-year-old boy who was treated for an erythematous, swollen, and severely painful ri
Externí odkaz:
https://doaj.org/article/24d5576557584ea1876b5ec205cb620b
Autor:
Debra L. Flock, Raul Chavez-Valdez, Frances J. Northington, Victoria Turnbill, Lee J. Martin, Daniella Asafu‐Adjaye, Panagiotis Kratimenos
Publikováno v:
J Comp Neurol
Neonatal hypoxic-ischemic encephalopathy (HIE) causes lifelong neurologic disability. Despite the use of therapeutic hypothermia, memory deficits and executive functions remain severely affected. Cholinergic neurotransmission from the basal forebrain