Ready, STAT3, Go! Bacteria in the race for M2 macrophage polarisation

Autor: Panagi, Ioanna, Thurston, Teresa LM

Publikováno v: In Current Opinion in Microbiology June 2023 73

A single amino acid in the Salmonella effector SarA/SteE triggers supraphysiological activation of STAT3 for anti-inflammatory target gene expression.

Autor: Gaggioli MR; Department of Molecular Genetics and Microbiology, School of Medicine, Duke University, Durham, NC 27710, USA., Jones AG; Department of Molecular Genetics and Microbiology, School of Medicine, Duke University, Durham, NC 27710, USA., Panagi I; Department of Infectious Disease, Centre for Bacterial Resistance Biology, Imperial College London, London, UK., Washington EJ; Department of Molecular Genetics and Microbiology, School of Medicine, Duke University, Durham, NC 27710, USA.; Department of Biochemistry, School of Medicine, Duke University, Durham, NC 27710, USA., Loney RE; Department of Molecular Genetics and Microbiology, School of Medicine, Duke University, Durham, NC 27710, USA., Muench JH; The Francis Crick Institute, London NW1 1AT, UK., Brennan RG; Department of Biochemistry, School of Medicine, Duke University, Durham, NC 27710, USA., Thurston TLM; Department of Infectious Disease, Centre for Bacterial Resistance Biology, Imperial College London, London, UK., Ko DC; Department of Molecular Genetics and Microbiology, School of Medicine, Duke University, Durham, NC 27710, USA.; Division of Infectious Diseases, Department of Medicine, School of Medicine, Duke University, Durham, NC 27710, USA.; Lead contact.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Feb 14. Date of Electronic Publication: 2024 Feb 14.