Zobrazeno 1 - 10
of 39
pro vyhledávání: '"PanIN, pancreatic intraepithelial neoplasia"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Pancreatic cancer is a very aggressive disease with 5-year survival rates of less than 10%. The constantly increasing incidence and stagnant patient outcomes despite changes in treatment regimens emphasize the requirement of a better understanding of
Externí odkaz:
https://doaj.org/article/ee2c60151b584f50933fbe927f90219c
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 2, Pp 369-382 (2022)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
The pancreas consists of several specialized cell types that display a remarkable ability to alter cellular identity in injury, regeneration, and repair. The abundant cellular plasticity within the pancreas appears to be exploited in tumorigenesis, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb5f0bff2cfc8c7cfadaaf0eb3440faa
https://doi.org/10.1016/j.jcmgh.2021.07.014
https://doi.org/10.1016/j.jcmgh.2021.07.014
Autor:
Megan T. Hoffman, Samantha B. Kemp, Daniel J. Salas-Escabillas, Yaqing Zhang, Nina G. Steele, Stephanie The, Daniel Long, Simone Benitz, Wei Yan, Robert F. Margolskee, Filip Bednar, Marina Pasca di Magliano, Hui-Ju Wen, Howard C. Crawford
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Pancreatic ductal adenocarcinoma (PDA) initiation and progression are accompanied by an immunosuppressive inflammatory response. Here, we evaluated the immunomodulatory role of chemosensory signaling in metaplastic tuft cells (MTCs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::686c6a10eefc99372b1badab6334bce4
https://doi.org/10.1016/j.jcmgh.2020.08.011
https://doi.org/10.1016/j.jcmgh.2020.08.011
Autor:
Marina Pasca di Magliano, Ben L. Allen, Filip Bednar, Hui-Ju Wen, Yaqing Zhang, Paloma E. Garcia, Howard C. Crawford, Michael K. Scales, Amara Z. Shaikh, Esther Kim, Yara S. El-Tawil, Maeva Adoumie, Deneen M. Wellik
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 3, Pp 581-599 (2020)
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 3, Pp 581-599 (2020)
Background & Aims Although the healthy pancreas consists mostly of epithelial cells, pancreatic cancer and the precursor lesions known as pancreatic intraepithelial neoplasia, are characterized by an extensive accumulation of fibroinflammatory stroma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18bb9a4858459dea9c49e9fd7caeb3bb
http://europepmc.org/articles/PMC7399194
http://europepmc.org/articles/PMC7399194
Publikováno v:
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Pancreatic cancer is a very aggressive disease with 5-year survival rates of less than 10%. The constantly increasing incidence and stagnant patient outcomes despite changes in treatment regimens emphasize the requirement of a better understanding of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e90dd1f242ff9f5b4b9c3c52af1817b
http://europepmc.org/articles/PMC8650502
http://europepmc.org/articles/PMC8650502
Autor:
Pankaj J. Pasricha, Yu-Wen Tien, Chi Che Hsieh, Subhash Kulkarni, Yung-Ming Jeng, Mei Hsin Chung, Ya Hsien Chou, Tsai Chen Chiang, King Siang Goh, Chia-Ning Shen, Hung Jen Chien, Chi Ruei Huang, Shih Jung Peng, Shiue-Cheng Tang, Chih Yuan Lee
Publikováno v:
EBioMedicine
Background The lymphatic system is involved in metastasis in pancreatic cancer progression. In cancer staging, lymphatic spread has been used to assess the invasiveness of tumor cells. However, from the endothelium's perspective, the analysis downpla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::decbe457f6ec2735f5478f710ca5467b
http://europepmc.org/articles/PMC6796580
http://europepmc.org/articles/PMC6796580
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Pancreatic ductal adenocarcinoma (PDA), the most common pancreatic cancer, is a nearly-universally lethal malignancy. PDA is characterized by extensive infiltration of immunosuppressive myeloid cells, including tumor-associated macrophages (TAMs) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8338a0adf80bef867d358e27be771c97
https://pubmed.ncbi.nlm.nih.gov/34303882
https://pubmed.ncbi.nlm.nih.gov/34303882
Autor:
Xing Liang, Hui Wang, Miaomiao Guo, Yongwei Sun, Ruimeng Yang, Yongheng Shi, Hui Shen, Ming Zhan, Qiang Liu, Linhua Yang
Publikováno v:
EBioMedicine
EBioMedicine, Vol 63, Iss, Pp 103195-(2021)
EBioMedicine, Vol 63, Iss, Pp 103195-(2021)
Background Pancreatic cancer (PC) is one of the most lethal solid malignancies in the world due to its excessive cell proliferation and aggressive metastatic features. Emerging evidences revealed the importance of posttranscriptional modifications of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc5cc90b669119ac79e8e7350cbe8a13
https://pubmed.ncbi.nlm.nih.gov/33418496
https://pubmed.ncbi.nlm.nih.gov/33418496
Publikováno v:
EBioMedicine
EBioMedicine, Vol 53, Iss, Pp-(2020)
EBioMedicine, Vol 53, Iss, Pp-(2020)
Pancreatic ductal adenocarcinoma (PDAC) shows remarkable propensity to metastasize. This predilection to escape from the primary tumor is driven by paracrine and autocrine mechanisms that guide cancer cells through a multi-step process concluding wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f38a4705938724fb049d0b00dcf2eb2
http://europepmc.org/articles/PMC7118576
http://europepmc.org/articles/PMC7118576