Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Pan-pan Tan"'
Autor:
Yun Song, Dan-Yi Chi, Ping Yu, Juan-Juan Lu, Jian-Rong Xu, Pan-Pan Tan, Bin Wang, Yong-Yao Cui, Hong-Zhuan Chen
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Histone deacetylase (HDAC) 2 plays a vital role in modifying histones to mediate inflammatory responses, while HDAC2 itself is commonly regulated by post-translational modifications. Small ubiquitin-related modifier (SUMO), as an important PTM factor
Externí odkaz:
https://doaj.org/article/77fe6eafdaa44cadbef0398fb961941e
Publikováno v:
Biological Trace Element Research. 197:115-122
The role of pro-inflammatory cytokines in the toxicity of fluoride to tumor cells was investigated by culturing Hepa1-6 cells in medium containing gradient concentrations of fluoride (0, 0.5, 1, 1.5, 2, 3, 4, and 5 mmol/L). The viability of Hepa1-6 c
Publikováno v:
Biological Trace Element Research.
C2C12 cells were cultured on medium containing fluoride (0, 1, and 2.5 mmol/L) for 48 h to investigate the effect of excessive fluoride on T helper 17 (Th17)-related cytokine expression profile in skeletal muscle cells, and the culture supernatant wa
Autor:
Lin Lin, Jing Zhao, Pan-pan Tan, Hong-wei Wang, Bian-hua Zhou, Jing Liu, Wen-peng Zhao, Wei-shun Tian
Publikováno v:
Chemosphere. 201:564-570
Our previous study indicated that excessive fluoride (F) induces ATP5J and ATP5H proactive expression by interfering cardiomyocyte mitochondrial dysfunction in mice. This study aimed to investigate underlying mechanisms of F¯ induced damage to cardi
Publikováno v:
Biological Trace Element Research. 185:440-447
This study was designed to investigate the mechanisms of excessive fluoride-induced apoptosis via mitochondria-mediated pathway in skeletal muscle cells (C2C12 cells). C2C12 cells were cultured with the fluoride concentrations (0, 1, and 2.5 mmol/L)
Publikováno v:
Chemosphere. 186:911-918
The present study was conducted to investigate the mechanisms of excessive-fluoride-induced reduction of oocyte development potential in mice. The development morphology of oocyte and the changes of pathomorphology in ovary were observed. The protein
Publikováno v:
Biological Trace Element Research. 178:253-260
A total of 84 healthy female mice were kept with various concentrations of sodium fluoride (F) (0, 50, 100, 150 mg F−/L in drinking water for 90 days) and were then mated with healthy male mice for 1 week to study the effect of excessive fluoride o
Autor:
Dan-Yi Chi, Ping Yu, Jianrong Xu, Yong-Yao Cui, Juan-Juan Lu, Bin Wang, Pan-Pan Tan, Hong-Zhuan Chen, Yun Song
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 10 (2019)
Frontiers in Pharmacology, Vol 10 (2019)
Histone deacetylase (HDAC) 2 plays a vital role in modifying histones to mediate inflammatory responses, while HDAC2 itself is commonly regulated by post-translational modifications. Small ubiquitin-related modifier (SUMO), as an important PTM factor
Autor:
Hao Wang, Wei Zhou, Hui Li, Pan-Pan Tan, Juan Li, Liang Zhu, Hongzhuan Chen, Jianrong Xu, Yong-Yao Cui, Yu Qiu, Xuan Zhang
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33(3)
SUMOylation is a significant post-translational modification (PTM) by the small ubiquitin-related modifier (SUMO). Increasing evidence shows SUMOylation regulates GPCR signaling; however, very few GPCRs have been shown to be SUMOylation targets to da
Publikováno v:
Chemosphere. 209
Excessive fluoride (F) intake decreases the development of potential oocytes by inducing oxidative stress and apoptosis in female mice in our previous study. This study aims to investigate the underlying mechanisms of F-induced follicular development