Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Pan A. Procopiou"'
Autor:
Nigel Stephen Stevenage Watson, Champa Patel, Steven John Coote, Henry Anderson Stevenage Kelly, Neil Anthony Pegg, Andrew Lowdon, William Leonard Mitchell, Rhian Thomas, Pamela J Thomas, Edward McDonald, Sean Hindley, Andrew Baxter, Martin Pass, Chi-Man Tang, Andrew P Craven, Harry Finch, Dawn A Walker, Christopher J. Mooney, Said Abu-Rabie, Harren Jhoti, Simon Parry, Pan A. Procopiou, Richard Conroy, Nigel G Ramsden
Publikováno v:
Bioorganicmedicinal chemistry letters. 9(12)
A series of trans-fused lactams containing the indane nucleus has been prepared. Compound 19 has much enhanced plasma stability compared with its lactone counterpart and shows appreciable in vitro anticoagulant activity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84d3e00bc5795729c712e852bf8850d0
https://pubmed.ncbi.nlm.nih.gov/10397495
https://pubmed.ncbi.nlm.nih.gov/10397495
Autor:
Nigel Stephen Stevenage Watson, Rona M. Highcock, Philip J. Sidebottom, Lane Stephen Joseph, Pan A. Procopiou
Publikováno v:
The Journal of antibiotics. 45(5)
Three novel fungal metabolites 1-3 isolated from cultures of a Phoma sp. C2932, are potent and selective inhibitors of squalene synthase. Their structures have been determined by a combination of spectroscopic, X-ray crystallographic and chemical met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::805aed3d8730c5f8f109b709204f8059
https://pubmed.ncbi.nlm.nih.gov/1624367
https://pubmed.ncbi.nlm.nih.gov/1624367