Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Pamila Brar"'
Autor:
Ilan Shomorony, Elizabeth T. Cirulli, Lei Huang, Lori A. Napier, Robyn R. Heister, Michael Hicks, Isaac V. Cohen, Hung-Chun Yu, Christine Leon Swisher, Natalie M. Schenker-Ahmed, Weizhong Li, Karen E. Nelson, Pamila Brar, Andrew M. Kahn, Timothy D. Spector, C. Thomas Caskey, J. Craig Venter, David S. Karow, Ewen F. Kirkness, Naisha Shah
Publikováno v:
Genome Medicine, Vol 12, Iss 1, Pp 1-14 (2020)
Abstract Background Modern medicine is rapidly moving towards a data-driven paradigm based on comprehensive multimodal health assessments. Integrated analysis of data from different modalities has the potential of uncovering novel biomarkers and dise
Externí odkaz:
https://doaj.org/article/658a898208d0476dad008393438c30cb
Autor:
Michael Doney, Ying-Chen Claire Hou, Pamila Brar, Bradley A. Perkins, Emily Y. Smith, Lori A. Napier, Christina Rybak, David S. Karow, C. Thomas Caskey, Weizhong Li, Keegan Duchicela, Saints Dominguez, Robyn Heister, Natalie M. Schenker-Ahmed, Richard J. Martin, Andrew M. Kahn, J. Craig Venter, Haibao Tang, Hung-Chun Yu, Christine Leon Swisher, Thomas J. Jönsson, Elizabeth T. Cirulli, Michael Hicks, Ewen F. Kirkness, Jaime Barea, Isaac V. Cohen, Nathaniel Hernandez
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance To understand the value and clinical impact of surveying genome-wide disease-causing genes and variants, we used a prospective cohort study design that enrolled volunteers who agreed to have their whole genome sequenced and to participat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2bc5b22481826fc594923514599700f
https://doi.org/10.1073/pnas.1909378117
https://doi.org/10.1073/pnas.1909378117
Autor:
Lei Huang, Weizhong Li, Lori A. Napier, Christine Leon Swisher, J. Craig Venter, Karen E. Nelson, Andrew M. Kahn, David S. Karow, Ewen F. Kirkness, Michael Hicks, Robyn Heister, Hung-Chun Yu, Pamila Brar, Tim D. Spector, Natalie M. Schenker-Ahmed, Isaac V. Cohen, Naisha Shah, Ilan Shomorony, Elizabeth T. Cirulli, C. Thomas Caskey
Publikováno v:
Genome Medicine
Genome Medicine, Vol 12, Iss 1, Pp 1-14 (2020)
Genome Medicine, Vol 12, Iss 1, Pp 1-14 (2020)
Background Modern medicine is rapidly moving towards a data-driven paradigm based on comprehensive multimodal health assessments. Integrated analysis of data from different modalities has the potential of uncovering novel biomarkers and disease signa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd5aa46bb37a66f8881b6bc704c69dab
http://europepmc.org/articles/PMC6953286
http://europepmc.org/articles/PMC6953286
Autor:
Shomorony, Ilan, Cirulli, Elizabeth, Huang, Lei, Napier, Lori, Heister, Robyn, Hicks, Michael, Cohen, Isaac, Hung-Chun Yu, Swisher, Christine, Schenker-Ahmed, Natalie, Weizhong Li, Nelson, Karen, Pamila Brar, Kahn, Andrew, Spector, Timothy, C. Caskey, J. Venter, Karow, David, Kirkness, Ewen, Naisha Shah
Additional file 1: Figure S1. Modularity score. Figure S2. Consensus matrix. Figure S3. Stratification of individuals. Figure S4. Subset membership. Figure S5. The cardiometabolic module. Figure S6. Prevalence of disease diagnoses. Figure S7. The mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::390ccb3973ef9078751258987f32dd3a
Autor:
Rybak C, Haibao Tang, Andrew M. Kahn, Barea J, Venter Jc, Michael Hicks, Thomas J. Jönsson, Caskey Ct, Robyn Heister, Pamila Brar, Ewen F. Kirkness, Hung-Chun Yu, Duchicela K, Christine Leon Swisher, Dominguez S, Weizhong Li, Elizabeth T. Cirulli, Doney M, Lori A. Napier, Natalie M. Schenker-Ahmed, Richard J. Martin, David S. Karow, Hernandez N, Cohen, Emily Y. Smith, Ying-Chen Claire Hou
We report the results of a three-year precision medicine study that enrolled 1190 presumed healthy participants at a single research clinic. To enable a better assessment of disease risk and improve diagnosis, a precision health platform that integra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aeec2e45cc7528ba7686474661325ab
Autor:
Axel Bernal, Andrea Procko, Julia Appis, Suzanne Brewerton, James Yu, C. Thomas Caskey, J. Craig Venter, Naisha Shah, David S. Karow, Victor Lavrenko, Claire Hou, James B. Brewer, Andrew M. Kahn, Gabby Hands, Istvan Bartha, Erin Coughlin, Bryan M. Wittmann, William H. Biggs, Smriti Ramakrishnan, Yaron Turpaz, Eric Dec, Anders M. Dale, Lining Guo, Thomas J. Jönsson, Pamila Brar, Bradley A. Perkins, Debbie Boeldt
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 115, iss 14
Perkins, BA; Caskey, CT; Brar, P; Dec, E; Karow, DS; Kahn, AM; et al.(2018). Precision medicine screening using whole-genome sequencing and advanced imaging to identify disease risk in adults. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 115(14), 3686-3691. doi: 10.1073/pnas.1706096114. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/77t291b8
Proceedings of the National Academy of Sciences of the United States of America
Perkins, BA; Caskey, CT; Brar, P; Dec, E; Karow, DS; Kahn, AM; et al.(2018). Precision medicine screening using whole-genome sequencing and advanced imaging to identify disease risk in adults. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 115(14), 3686-3691. doi: 10.1073/pnas.1706096114. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/77t291b8
Proceedings of the National Academy of Sciences of the United States of America
Significance Advances in technology are enabling evaluation for prevention and early detection of age-related chronic diseases associated with premature mortality, such as cancer and cardiovascular diseases. These diseases kill about one-third of men
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db38f44454d384e5a95012459bff6d5d
https://escholarship.org/uc/item/77t291b8
https://escholarship.org/uc/item/77t291b8
Autor:
Suzanne Brewerton, James Yu, Yaron Turpaz, Claire Hou, J. Craig Venter, Andrew M. Kahn, Amalio Telenti, C. Thomas Caskey, Anders M. Dale, David S. Karow, Axel Bernal, Thomas J. Jönsson, Debbie Boeldt, Naisha Shah, Istvan Bartha, Gabby Hands, Erin Coughlin, James B. Brewer, Bryan M. Wittmann, Victor Lavrenko, Pamila Brar, Julia Appis, Bradley A. Perkins, Lining Guo, Eric Dec, Smriti Ramakrishnan, Andrea Procko, William H. Biggs
BACKGROUNDProgress in science and technology have created the capabilities and alternatives to symptom-driven medical care. Reducing premature mortality associated with age-related chronic diseases, such as cancer and cardiovascular disease, is an ur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::934c074e2d716ff254ecce1a57b31cbb
https://doi.org/10.1101/133538
https://doi.org/10.1101/133538