Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Pamela Y. Jenkinson"'
Autor:
D. Hardy, Brian R. Clark, Pamela Y. Jenkinson, Shao-Chia Chou, Hilary L. Ashe, Roberts A. Smith, Barbara C. Halpern, Richard M. Halpern
Publikováno v:
Proceedings of the National Academy of Sciences. 72:4018-4022
The selective toxicity of antifolates for a variety of cancers can be improved, as illustrated by the combined administration of N5-methyltetrahydrofolate and methotrexate in tissue culture. When a variety of neoplastic cell types characterized by a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f71da57515c7da4f4b812fadd4762254
https://doi.org/10.1073/pnas.72.10.4018
https://doi.org/10.1073/pnas.72.10.4018
Publikováno v:
Biochemical and biophysical research communications. 46(2)
Summary A non-dialyzable tRNA methylase inhibitor was isolated from normal adult rat liver. The inhibition caused by this factor was eliminated on prolonged dialysis. However, when nicotinamide was added back to the dialyzed fraction, the inhibitory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9953f2f5da114353407a65835686f5ed
https://pubmed.ncbi.nlm.nih.gov/4257994
https://pubmed.ncbi.nlm.nih.gov/4257994