Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Pamela Veneziano-Broccia"'
Autor:
Antoine Claessens, Lynne M Harris, Slavica Stanojcic, Lia Chappell, Adam Stanton, Nada Kuk, Pamela Veneziano-Broccia, Yvon Sterkers, Julian C Rayner, Catherine J Merrick
Publikováno v:
PLoS Genetics, Vol 14, Iss 7, p e1007490 (2018)
The malaria parasite Plasmodium falciparum has evolved an unusual genome structure. The majority of the genome is relatively stable, with mutation rates similar to most eukaryotic species. However, some regions are very unstable with high recombinati
Externí odkaz:
https://doaj.org/article/7d4cdc43a6e547ebbcf08ca74b449fcd
Autor:
Eleonora Petti, Valentina Buemi, Antonina Zappone, Odessa Schillaci, Pamela Veneziano Broccia, Roberto Dinami, Silvia Matteoni, Roberta Benetti, Stefan Schoeftner
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
LncRNA TERRA forms RNA-DNA hybrids at telomere sites leading to telomere instability. Here the authors identify the RNA interacting factors NONO and SFPQ as proteins that interact with TERRA and telomere chromatin and reveal putative roles for these
Externí odkaz:
https://doaj.org/article/f8f8d328c17a48d78dd6073e811e9d80
Autor:
Valentina Buemi, Odessa Schillaci, Mariangela Santorsola, Deborah Bonazza, Pamela Veneziano Broccia, Annie Zappone, Cristina Bottin, Giulia Dell’Omo, Sylvie Kengne, Stefano Cacchione, Grazia Daniela Raffa, Silvano Piazza, Fabrizio d’Adda di Fagagna, Roberta Benetti, Maurizio Cortale, Fabrizio Zanconati, Giannino Del Sal, Stefan Schoeftner
Pathways that direct the selection of the telomerase-dependent or recombination-based, alternative lengthening of telomere (ALT) maintenance pathway in cancer cells are poorly understood. Using human lung cancer cells and tumor organoids we show that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3c7e24cdfd09acf3b99826cbe09be3b
https://hdl.handle.net/11368/3019031
https://hdl.handle.net/11368/3019031
Autor:
Odessa Schillaci, Stefan Schoeftner, Silvia Matteoni, Valentina Buemi, Roberto Dinami, Eleonora Petti, Roberta Benetti, Pamela Veneziano Broccia, Antonina Zappone
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications
In vertebrates, the telomere repeat containing long, non-coding RNA TERRA is prone to form RNA:DNA hybrids at telomeres. This results in the formation of R-loop structures, replication stress and telomere instability, but also contributes to alternat