Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Pamela V, Martino Adami"'
Autor:
Pamela V. Martino-Adami, Madhurima Chatterjee, Luca Kleineidam, Siegfried Weyerer, Horst Bickel, Birgitt Wiese, Steffi G. Riedel-Heller, Martin Scherer, Kaj Blennow, Henrik Zetterberg, Michael Wagner, Anja Schneider, Alfredo Ramirez
Publikováno v:
The Lancet Regional Health. Europe, Vol 45, Iss , Pp 101030- (2024)
Summary: Background: Blood-based biomarkers offer a promising, less invasive, and more cost-effective alternative for Alzheimer's disease screening compared to cerebrospinal fluid or imaging biomarkers. However, they have been extensively studied onl
Externí odkaz:
https://doaj.org/article/aa00114e412345fe868b106fa094c71c
Autor:
Amanda Cano, Ester Esteban-de-Antonio, Mireia Bernuz, Raquel Puerta, Pablo García-González, Itziar de Rojas, Claudia Olivé, Alba Pérez-Cordón, Laura Montrreal, Raúl Núñez-Llaves, Óscar Sotolongo-Grau, Emilio Alarcón-Martín, Sergi Valero, Montserrat Alegret, Elvira Martín, Pamela V. Martino-Adami, Miren Ettcheto, Antonio Camins, Assumpta Vivas, Marta Gomez-Chiari, Miguel Ángel Tejero, Adelina Orellana, Lluís Tárraga, Marta Marquié, Alfredo Ramírez, Mercè Martí, María Isabel Pividori, Mercè Boada, Agustín Ruíz
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-19 (2023)
Highlights The pEVs proteome revealed early molecular differences between EOMCI Aβ( +) and Aβ(-) subjects. Olink© neurology proteins from pEVs of EOMCI Aβ( +) patients exhibited a strong negative correlation with CSF p-tau181. The levels of pEVs
Externí odkaz:
https://doaj.org/article/fe94db07000c43398bdc01449eceb2ce
Autor:
María C. Dalmasso, Martín Arán, Pablo Galeano, Silvina Perin, Patrick Giavalisco, Pamela V. Martino Adami, Gisela V. Novack, Eduardo M. Castaño, A. Claudio Cuello, Martin Scherer, Wolfgang Maier, Michael Wagner, Steffi Riedel-Heller, Alfredo Ramirez, Laura Morelli
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2023)
Introduction: The metabolic routes altered in Alzheimer's disease (AD) brain are poorly understood. As the metabolic pathways are evolutionarily conserved, the metabolic profiles carried out in animal models of AD could be directly translated into hu
Externí odkaz:
https://doaj.org/article/c97efebf6eb0455290958f433544b64d
Autor:
Pablo García-González, Itziar de Rojas, Sonia Moreno-Grau, Laura Montrreal, Raquel Puerta, Emilio Alarcón-Martín, Inés Quintela, Adela Orellana, Victor Andrade, Pamela V. Martino Adami, Stefanie Heilmann-Heimbach, Pilar Gomez-Garre, María Teresa Periñán, Ignacio Alvarez, Monica Diez-Fairen, Raul Nuñez Llaves, Claudia Olivé Roig, Guillermo Garcia-Ribas, Manuel Menéndez-González, Carmen Martínez, Miquel Aguilar, Mariateresa Buongiorno, Emilio Franco-Macías, Maria Eugenia Saez, Amanda Cano, Maria J. Bullido, Luis Miguel Real, Eloy Rodríguez-Rodríguez, Jose Luís Royo, Victoria Álvarez, Pau Pastor, Gerard Piñol-Ripoll, Pablo Mir, Miguel Calero Lara, Miguel Medina Padilla, Pascual Sánchez-Juan, Angel Carracedo, Sergi Valero, Isabel Hernandez, Lluis Tàrraga, Alfredo Ramirez, Mercé Boada, Agustín Ruiz
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 898 (2023)
Mosaic loss of chromosome Y (mLOY) is a common ageing-related somatic event and has been previously associated with Alzheimer’s disease (AD). However, mLOY estimation from genotype microarray data only reflects the mLOY degree of subjects at the mo
Externí odkaz:
https://doaj.org/article/c8c4eaad08a8470cafc3738e4c60364f
Autor:
Benjamin Schmid, Bjørn Holst, Christian Clausen, Lamiaa Bahnassawy, Peter Reinhardt, Margot H.M. Bakker, Eva Díaz-Guerra, Carlos Vicario, Pamela V. Martino-Adami, Michaela Thoenes, Alfredo Ramirez, Klaus Flissbach, Clara Grezella, Oliver Brüstle, Michael Peitz, Andreas Ebneth, Alfredo Cabrera-Socorro
Publikováno v:
Stem Cell Research, Vol 52, Iss , Pp 102180- (2021)
APOE genotype is the strongest genetic risk factor for Alzheimer’s Disease (AD). The low degree of homology between mouse and human APOE is a concerning issue in preclinical models currently used to study the role of this gene in AD pathophysiology
Externí odkaz:
https://doaj.org/article/ba2956d805ec4ac18265889ef69b2545
Autor:
María Victoria Rosato-Siri, Pamela V. Martino Adami, María Eugenia Guitart, Sandra Verstraeten, Laura Morelli, Jorge Correale, Juana María Pasquini
Publikováno v:
Molecular Neurobiology. 60:1949-1963
Iron deficiency (ID) represents one of the most prevalent nutritional deficits, affecting almost two billion people worldwide. Gestational iron deprivation induces hypomyelination due to oligodendroglial maturation deficiencies and is thus a useful e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a1e9acb84e6be2ad65e6068bce03dbe
https://doi.org/10.1007/s12035-022-03149-y
https://doi.org/10.1007/s12035-022-03149-y
Autor:
Philippe Amouyel, Pablo Garcia-Gonzalez, Qiong Yang, Joshua C. Bis, Alfredo Ramírez, Luca Kleineidam, Carmen Antúnez-Almagro, Myriam Fornage, Claudia L. Satizabal, Adela Orellana, Rebecca Sims, Juan Marín-Muñoz, Julie Williams, Eric Boerwinkle, Céline Bellenguez, María Eugenia Sáez, Laura Madrid, Rui Xia, Luis Miguel Real, Janina S. Ried, Xueqiu Jian, Shahzad Ahmad, M. Arfan Ikram, Sonia Moreno-Grau, Alzheimer’s Disease Neuroimaging Initiative (Adni), Cornelia M Van Duijn, Sudha Seshadri, Pamela V. Martino Adami, Vincent Damotte, Anita L. DeStefano, Itziar de Rojas, Benjamin Grenier-Boley, Antonio González-Pérez, Agustín Ruiz, Alfredo Cabrera-Socorro, Fuensanta Noguera-Perea, Jean-Charles Lambert
Publikováno v:
Aging 13(7), 9277-9329 (2021). doi:10.18632/aging.202950
Aging, 13(7), 9277-9329. Impact Journals LLC
Aging (Albany NY)
Aging
Aging, 13(7), 9277-9329. Impact Journals LLC
Aging (Albany NY)
Aging
Alzheimer’s disease (AD) is the most common form of dementia, currently affecting 35 million people worldwide. Apolipoprotein E (APOE) ε4 allele is the major risk factor for sporadic, late-onset AD (LOAD), which comprises over 95% of AD cases, inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6cc3dfc4e5c71d57c01cf188af46736
https://doi.org/10.18632/aging.202950
https://doi.org/10.18632/aging.202950
Autor:
Michelle Gerards, Ann‐Katrin Schild, Dix U. Meiberth, Ayda Rostamzadeh, Jörg Janne Vehreschild, Sebastian Wingen‐Heimann, Pamela V. Martino Adami, Oezguer A. Onur, Alfredo Ramirez, Thomas K. Karikari, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Franziska Maier, Frank Jessen
Publikováno v:
Alzheimer's & Dementia. 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6474be1128a3b4866268fd7584a8654
https://doi.org/10.1002/alz.055520
https://doi.org/10.1002/alz.055520
Matrix metalloproteinase 10 is linked to the risk of progression to dementia of the Alzheimer's type
Autor:
Pamela V Martino Adami, Adelina Orellana, Pablo García, Luca Kleineidam, Emilio Alarcón-Martín, Laura Montrreal, Nuria Aguilera, Ana Espinosa, Carla Abdelnour, Maitee Rosende-Roca, Juan Pablo Tartari, Liliana Vargas, Ana Mauleón, Ester Esteban-De Antonio, Rogelio López-Cuevas, Maria Carolina Dalmasso, Rafael Campos Martin, Kayenat Parveen, Victor M Andrade Fuentes, Najaf Amin, Shahzad Ahmad, M Arfan Ikram, Piotr Lewczuk, Johannes Kornhuber, Oliver Peters, Lutz Frölich, Eckart Rüther, Jens Wiltfang, Lluis Tarraga, Merce Boada, Wolfgang Maier, Itziar de Rojas, Amanda Cano, Angela Sanabria, Montserrat Alegret, Isabel Hernández, Marta Marquié, Sergi Valero, Cornelia M van Duijn, Michael Wagner, Frank Jessen, Anja Schneider, María Eugenia Sáez Goñi, Antonio González Pérez, Agustín Ruiz, Alfredo Ramírez
Publikováno v:
Brain, 145(7), 2507-2517. Oxford University Press
Brain 145(7), 2507-2517 (2022). doi:10.1093/brain/awac024
Brain 145(7), 2507-2517 (2022). doi:10.1093/brain/awac024
Alzheimer’s disease has a long asymptomatic phase that offers a substantial time window for intervention. Using this window of opportunity will require early diagnostic and prognostic biomarkers to detect Alzheimer’s disease pathology at predemen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08aad64db112f155981c2f2b73b7634c
https://pubmed.ncbi.nlm.nih.gov/35088840
https://pubmed.ncbi.nlm.nih.gov/35088840
Autor:
Martin Aran, Silvia Perin, Laura Morelli, Pamela V. Martino Adami, Maria Carolina Dalmasso, Patick Giavalisco, Pablo Galeano, Martin Scherer, Alfredo Ramirez, W. Maier, Steffi Reidel-Heller, A. Claudio Cuello, Eduardo Migual Castano, Michael Wagner
Background: The metabolic routes altered in Alzheimer's disease (AD) brain are poorly understood. As the metabolic pathways are evolutionarily conserved, the metabolic profiles carried out in animal models of AD could be directly translated into huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd91806f55f009de85142b9e650b37b2
https://doi.org/10.21203/rs.3.rs-518284/v2
https://doi.org/10.21203/rs.3.rs-518284/v2
