Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Pamela Thébault"'
Autor:
Mayra S. Carneiro, Yacine Bareche, Cheng Zhao, Pamela Thébault, Kurosh Rahimi, Diane Provencher, Vanessa Samouélian, Béatrice Cormier, Jean-François Cailhier, Anne-Marie Mes-Masson, Sophie Petropoulos, John Stagg, Réjean Lapointe
Characterizing T cell populations and understanding their developmental relationships may help design more effective cancer immunotherapies. We coupled single-cell transcriptomics and T cell receptor (TCR) αβ profiling of intratumoral and periphera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbaa2f565d3879c2b0a0f9cc1f01bcb3
https://doi.org/10.1101/2023.02.28.530488
https://doi.org/10.1101/2023.02.28.530488
Autor:
Tingting Chen, Marie Hudson, Rejean Lapointe, Wilson H Miller, Pamela Thebault, Khashayar Esfahani, Jun Ding, Lucas A Salas, Steph A Pang, Manuel Flores Molina, Hsiang Chou, Christophe Goncalves, Paulo Nunes Filho, Sabin Filimon, Caroline M Michel, Sonia VDel Rincon
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/55c2d868a2274df890da2bde8d0b8327
Autor:
Typhaine Gris, Patrick Laplante, Paméla Thebault, Romain Cayrol, Ahmed Najjar, Benjamin Joannette-Pilon, Frédéric Brillant-Marquis, Elsa Magro, Shane W. English, Réjean Lapointe, Michel Bojanowski, Charles L. Francoeur, Jean-François Cailhier, on behalf of the Canadian Critical Care Translational Biology Group
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-16 (2019)
Abstract Background Aneurysmal subarachnoid hemorrhage (SAH) is a catastrophic disease with devastating consequences, including a high mortality rate and severe disabilities among survivors. Inflammation is induced following SAH, but the exact role a
Externí odkaz:
https://doaj.org/article/cf807618ddec4f168a80da39fe6b4434
Autor:
Khashayar Esfahani, Tho-Alfakar Al-Aubodah, Pamela Thebault, Réjean Lapointe, Marie Hudson, Nathalie A. Johnson, Dana Baran, Najwa Bhulaiga, Tomoko Takano, Jean-François Cailhier, Ciriaco A. Piccirillo, Wilson H. Miller
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
The use of immune checkpoint inhibitors (ICI) in cancer patients with solid organ allografts is hampered due to potential organ rejection. Here, the authors present a case report of a patient with kidney allograft and show that treatment with the mTO
Externí odkaz:
https://doaj.org/article/7b6d74e8eca445f991f3a9a988480cef
Autor:
John Stagg, Anne-Marie Mes-Masson, Rejean Lapointe, Pamela Thebault, David Allard, Isabelle Cousineau, Yacine Bareche, Sandra Pommey, Mayra Carneiro, Laurence Buisseret, Pavel Chrobak, Laudine Communal, Simon C Robson, Diane Provencher
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 3 (2021)
Background Hydrolysis of extracellular ATP to adenosine (eADO) is an important immune checkpoint in cancer immunology. We here investigated the impact of the eADO pathway in high-grade serous ovarian cancer (HGSC) using multiparametric platforms.Meth
Externí odkaz:
https://doaj.org/article/79a64e0d29404bbdb5f83e93f3d2960a
Autor:
David Possamaï, Laïla-Aïcha Hanafi, Angélique Bellemare-Pelletier, Katia Hamelin, Paméla Thébault, Marie-Josée Hébert, Étienne Gagnon, Denis Leclerc, Réjean Lapointe
Publikováno v:
PLoS ONE, Vol 16, Iss 12 (2021)
Nanoparticles made of the coat protein of papaya mosaic virus (PapMV) and a single-strand RNA were previously shown to be an efficient antigen presentation system for the trigger of cellular immunity. Engineering of PapMV nano with a cytotoxic T lymp
Externí odkaz:
https://doaj.org/article/077699753b6e422fb8dd35551db34f88
Autor:
Rahima Jamal, Réjean Lapointe, Eftihia Cocolakis, Paméla Thébault, Shirin Kazemi, Jennifer E. Friedmann, Jeanne Dionne, Jean-François Cailhier, Karl Bélanger, Jean-Pierre Ayoub, Huy Le, Caroline Lambert, Jida El-Hajjar, Léon C. van Kempen, Alan Spatz, Wilson H. Miller
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 5, Iss 1, Pp 1-13 (2017)
Abstract Background Checkpoint blockade with ipilimumab provides long-term survival to a significant proportion of patients with metastatic melanoma. New approaches to increase survival and to predict which patients will benefit from treatment are ne
Externí odkaz:
https://doaj.org/article/c038d5dcfb704f2aaa6e6160d6d158ec
Autor:
Miriam Marquis, Salix Boulet, Simon Mathien, Justine Rousseau, Paméla Thébault, Jean-François Daudelin, Julie Rooney, Benjamin Turgeon, Claudine Beauchamp, Sylvain Meloche, Nathalie Labrecque
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86681 (2014)
The classical mitogen-activated protein kinases (MAPKs) ERK1 and ERK2 are activated upon stimulation of cells with a broad range of extracellular signals (including antigens) allowing cellular responses to occur. ERK3 is an atypical member of the MAP
Externí odkaz:
https://doaj.org/article/bf49f1204adc4e9a90c201b2691e7067
Autor:
Mohammad-Ali Jenabian, Mital Patel, Ido Kema, Cynthia Kanagaratham, Danuta Radzioch, Paméla Thébault, Réjean Lapointe, Cécile Tremblay, Norbert Gilmore, Petronela Ancuta, Jean-Pierre Routy
Publikováno v:
PLoS ONE, Vol 9, Iss 1 (2014)
Externí odkaz:
https://doaj.org/article/d744ed9791464608825ff81ffd300ca2
Autor:
Mohammad-Ali Jenabian, Mital Patel, Ido Kema, Cynthia Kanagaratham, Danuta Radzioch, Paméla Thébault, Réjean Lapointe, Cécile Tremblay, Norbert Gilmore, Petronela Ancuta, Jean-Pierre Routy
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e78146 (2013)
Tryptophan (Trp) catabolism into immunosuppressive kynurenine (Kyn) by indoleamine 2,3-dioxygenase (IDO) was previously linked to Th17/Treg differentiation and immune activation. Here we examined Trp catabolism and its impact on Th17/Treg balance in
Externí odkaz:
https://doaj.org/article/d8eb9a8e4b6344818b2e22706cbaa9f1