Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Pamela Strein"'
Publikováno v:
Experimental Dermatology. 12:529-536
Xeroderma pigmentosum (XP) is an autosomal recessive disease characterized by sun sensitivity, early onset of freckling and subsequent neoplastic changes on sun-exposed skin. Skin abnormalities result from an inability to repair UV-damaged DNA becaus
Autor:
Christian Klein, Roger Grau, Christopher Del Nagro, Sibrand Poppema, Joseph Dal Porto, Claudia Ferrara, Samuel Moser, Carla Schmidt, Karim Dabbagh, Peter Sondermann, Thomas Friess, Pablo Umana, Ursula Püntener, Pamela Strein, Sabine Bauer, Martin J. S. Dyer, Christian Gerdes, Sylvia Herter, Erwin van Puijenbroek, Adam Nopora, Ekkehard Mössner, Christine Schüll, Christiane Jäger, Peter Brünker, Georg Fertig
Publikováno v:
Blood, 115(22), 4393-4402. AMER SOC HEMATOLOGY
CD20 is an important target for the treatment of B-cell malignancies, including non-Hodgkin lymphoma as well as autoimmune disorders. B-cell depletion therapy using monoclonal antibodies against CD20, such as rituximab, has revolutionized the treatme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cd7831bff1600251006b7d63294a29b
https://research.rug.nl/en/publications/49d71233-c3dd-4871-962a-87f938a35668
https://research.rug.nl/en/publications/49d71233-c3dd-4871-962a-87f938a35668
Publikováno v:
Experimental dermatology. 12(5)
Xeroderma pigmentosum (XP) is an autosomal recessive disease characterized by sun sensitivity, early onset of freckling and subsequent neoplastic changes on sun-exposed skin. Skin abnormalities result from an inability to repair UV-damaged DNA becaus
Autor:
Christian Klein, Joe DalPorto, Karim Dabbagh, Thomas Friess, Georg Fertig, Pamela Strein, Manfred Kubbies, Sabine Bauer, Sibrand Poppema, Martin J.S. Dyer, Luise Wheat, Peter Sondermann, Samuel Moser, Monika Patre, Adam Nopora, Christian Gerdes, Sylvia Herter, Carla Schmidt, Roger Grau, Tobias Suter, Puentener Ursula, Klingner Gabriele, Bruenker Peter, Moessner Ekkehard, Pablo Umana
Publikováno v:
Blood. 110:2348-2348
GA101 is a novel monoclonal antibody of IgG1 type which binds with high affinity and selectivity to the extracellular domain of the human CD20 antigen on B cells. In contrast to rituximab which is a chimeric antibody and recognizes a type I epitope,
Autor:
Peter Sondermann, Christian Klein, Thomas Friess, Martin J. S. Dyer, Luise Wheat, Samuel Moser, Ekkehard Moessner, Pamela Strein, Tobias Suter, Christian Gerdes, Monika Patre, Sibrand Poppema, Sabine Bauer, Adam Nopora, Peter Bruenker, Ursula Puentener, Carla Schmidt, Roger Grau, Pablo Umana, Gabriele Unsin
Publikováno v:
Blood. 108:229-229
Background: Treatment of B-cell non-Hodgkin lymphoma (NHL) with antibodies targeting CD20 in conjunction with combination chemotherapy is standard clinical practice. Two different types of CD20 MAb differing significantly in their mode of CD20 bindin