Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Pamela St. Jean"'
Autor:
Carlos Cruchaga, Gabe Haller, Sumitra Chakraverty, Kevin Mayo, Francesco L M Vallania, Robi D Mitra, Kelley Faber, Jennifer Williamson, Tom Bird, Ramon Diaz-Arrastia, Tatiana M Foroud, Bradley F Boeve, Neill R Graff-Radford, Pamela St Jean, Michael Lawson, Margaret G Ehm, Richard Mayeux, Alison M Goate, NIA-LOAD/NCRAD Family Study Consortium
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31039 (2012)
Pathogenic mutations in APP, PSEN1, PSEN2, MAPT and GRN have previously been linked to familial early onset forms of dementia. Mutation screening in these genes has been performed in either very small series or in single families with late onset AD (
Externí odkaz:
https://doaj.org/article/00e347ba0885474d87ad4841483412db
Autor:
Carlos Cruchaga, Sumitra Chakraverty, Kevin Mayo, Francesco L. M. Vallania, Robi D. Mitra, Kelley Faber, Jennifer Williamson, Tom Bird, Ramon Diaz-Arrastia, Tatiana M. Foroud, Bradley F. Boeve, Neill R. Graff-Radford, Pamela St. Jean, Michael Lawson, Margaret G. Ehm, Richard Mayeux, Alison M. Goate
Publikováno v:
PLoS ONE, Vol 7, Iss 5 (2012)
Externí odkaz:
https://doaj.org/article/c603c58fe7fa4ca0935f074ff6238281
Autor:
Astrid Yeo, Mathias Chiano, Dana J. Fraser, Soumitra Ghosh, Neil Martin, David A. Lipson, Charles Cox, Joshua Hoffman, Pamela St Jean, Lynn D. Condreay, Louise Hosking
Publikováno v:
Respiratory Medicine. 187:106573
Background Combination treatments, targeting multiple disease processes, benefit subjects with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). However, predicting treatment response and exacerbation risk remain challenging. Obje
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d3bd126e968716b9f81a682c128822
https://doi.org/10.1016/j.rmed.2021.106573
https://doi.org/10.1016/j.rmed.2021.106573
Autor:
Pamela St. Jean, Agnes J. Thomas, Richard J. Koletsky, Nicholas J. Schork, Evelyn H. Schlenker, Kingman P. Strohl
Publikováno v:
Journal of Applied Physiology. 82:317-323
Strohl, Kingman P., Agnes J. Thomas, Pamela St. Jean, Evelyn H. Schlenker, Richard J. Koletsky, and Nicholas J. Schork.Ventilation and metabolism among rat strains. J. Appl. Physiol. 82(1): 317–323, 1997.—We examined ventilation and metabolism in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3279b699681d0a7c3275d9a801e1b994
https://doi.org/10.1152/jappl.1997.82.1.317
https://doi.org/10.1152/jappl.1997.82.1.317
Autor:
Thomas N. Ferraro, Pamela St. Jean, Christos Ballas, Jörg Schill, George G. Smith, Nicole Mulholland, Nicholas J. Schork, Russell J. Buono, Gregory T. Golden, Wade H. Berrettini
Publikováno v:
The Journal of Neuroscience. 19:6733-6739
DBA/2J (D2) and C57BL/6J (B6) mice exhibit differential sensitivity to seizures induced by various chemical and physical methods, with D2 mice being relatively sensitive and B6 mice relatively resistant. We conducted studies in mature D2, B6, F1, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::739da38868f8dd1db938de7367aa1405
https://doi.org/10.1523/jneurosci.19-16-06733.1999
https://doi.org/10.1523/jneurosci.19-16-06733.1999
Autor:
Barbara K. Stubblefield, Inna Dymarskaia, Marzena Galdzicka, Robert Long, Maria C. H. Anderson, Pamela St. Jean, Nicholas J. Schork, Brian M. Martin, Melissa Ehlert, Bonnie Thiel, Edward I. Ginns, Brian G. Remortel, Robert C. Elston, Cathy S.J. Fann, Loring J. Ingraham, Harnisha Dalwaldi, Abram M. Hostetter, Ashima P. Patel, Melissa A. Murray, Lucy G. Lacy, Sharon P. Paul, Cleona R. Allen, Janice A. Egeland, Elaine Lau, Tim Keith, Kathleen M. Falls, John P. Carulli, Cary Shaio, Robert A. Philibert, Patricia Damschroder-Williams, Steven M. Paul
Publikováno v:
Proceedings of the National Academy of Sciences. 95:15531-15536
Bipolar affective disorder (BPAD; manic-depressive illness) is characterized by episodes of mania and/or hypomania interspersed with periods of depression. Compelling evidence supports a significant genetic component in the susceptibility to develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb39d5b60674a67a951c10e4a498baf6
https://doi.org/10.1073/pnas.95.26.15531
https://doi.org/10.1073/pnas.95.26.15531
Autor:
Robert C. Elston, David B. Allison, Nicholas J. Schork, Pamela St. Jean, Ming C. Infante, Bonnie Thiel
Publikováno v:
The American Journal of Human Genetics. 63:1190-1201
SummaryGenomewide searches for loci influencing complex human traits and diseases such as diabetes, hypertension, and obesity are often plagued by low power and interpretive difficulties. Attempts to remedy these difficulties have typically relied on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32df5f7a9545adecd0306bab4ed1654a
https://doi.org/10.1086/302038
https://doi.org/10.1086/302038
Publikováno v:
Scopus-Elsevier
Although all meiotic (or linkage) mapping strategies ultimately rely on Mendel's laws, the precise manner in which these laws are exploited in relevant statistical models determines the utility of each strategy for different traits and diseases. In t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e376abdbd85a5f22efd6eceff14ef375
https://doi.org/10.1002/(sici)1097-010x(199809/10)282:1/2<133::aid-jez15>3.0.co
https://doi.org/10.1002/(sici)1097-010x(199809/10)282:1/2<133::aid-jez15>3.0.co
Autor:
Carlos Cruchaga, Sumitra Chakraverty, Kevin Mayo, Francesco L. M. Vallania, Robi D. Mitra, Kelley Faber, Jennifer Williamson, Tom Bird, Ramon Diaz-Arrastia, Tatiana M. Foroud, Bradley F. Boeve, Neill R. Graff-Radford, Pamela St. Jean, Michael Lawson, Margaret G. Ehm, Richard Mayeux, Alison M. Goate, for the NIA-LOAD/NCRAD Family Study Consortium
Publikováno v:
PLoS ONE, Vol 7, Iss 5 (2012)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::c402e6f459be717fead95f6b681503f7
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351480/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351480/?tool=EBI
Publikováno v:
Drug discovery today. 10(3)
Relevance of a drug target for a disease is often inferred with strong belief but fragile evidence. Here, a program for early identification of human disease-specific drug targets using high-throughput genetic associations is described. Large numbers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::00e6bc6ab3832207ef6dd93d6d579d4b
https://pubmed.ncbi.nlm.nih.gov/15708532
https://pubmed.ncbi.nlm.nih.gov/15708532