Výsledky vyhledávání - "Pamela S. Shaw"

Abstract 1756: Antitumor effect of XMT1660, a B7H4 targeting antibody drug conjugate, in an unselected panel of patient derived xenograft models of breast cancer

Autor: Scott D. Collins, Pamela S. Shaw, Shawn P. Fessler, Jason Wang, Rebecca Mosher

Publikováno v: Cancer Research. 82:1756-1756

Introduction: XMT-1660 is a first-in-class Dolasynthen Antibody-Drug Conjugate (ADC) targeting B7-H4 and carrying a DolaLock payload with controlled bystander effect. B7-H4 is an immunoregulatory protein that is expressed in breast, ovarian and endom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6b4e8ef4af89387fd2407a5410e1065d
https://doi.org/10.1158/1538-7445.am2022-1756

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Abstract 821: Loss and retention of mutations in cell culture model systems

Autor: Agoston T. Agoston, Rick Nicoletti, Abigail E. Witt, Pamela S. Shaw, Helen L. Yang, Naghmeh Salimi, Elin S. Agoston

Publikováno v: Cancer Research. 77:821-821

Although relevant, the genomic and proteomic alterations between original tumor tissue and newly established cell lines are frequently uncharacterized. In developing a novel cell model (Powder) of high grade serous carcinoma (HGSC), we followed the s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9f09a3d924399cb1fbedf5e077abd23d
https://doi.org/10.1158/1538-7445.am2017-821

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