Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Pamela S. Newman"'
Publikováno v:
Clinical and Experimental Hypertension. 19:297-312
This study examined the temporal effects of the polyamine synthesis inhibitor eflornithine (alpha-difluoromethylornithine) on vascular responses to KCI, norepinephrine, sodium nitroprusside and acetylcholine in aortic rings from coarctation hypertens
Publikováno v:
Clinical and Experimental Hypertension. 16:595-610
This study was performed to assess the potential role of polyamines in the alterations in vascular structure and function in spontaneously hypertensive rats (SHR). The effects of chronic administration of eflornithine (alpha-difluoromethylornithine;
Publikováno v:
Developmental Pharmacology and Therapeutics. 20:107-110
The chronic effects of short-term administration of a high salt diet to postweaning rats on blood pressure (BP) was studied. BP was significantly elevated following 4 weeks of treatment. After stopping the high salt diet, BP dropped to control levels
Publikováno v:
Life Sciences. 53:PL303-PL307
Numerous studies have been reported examining the effects of antihypertensive treatment on peripheral vascular responsiveness in spontaneously hypertensive rats (SHR). This study was conducted to determine the effects of chronic treatment with 2 anti
Autor:
Pamela S. Newman, Edward E. Soltis
Publikováno v:
Developmental Pharmacology and Therapeutics. 18:44-54
This study investigated the ontogeny of contractile and relaxation responses in aortic and tail artery preparations from 3-, 7-, and 11-week-old male Sprague-Dawley rats. Contractile responses to norepinephrine, serotonin, KCl, electrical stimulation
Publikováno v:
Hypertension. 18:85-92
This study was performed to determine if an alteration in vascular polyamine contents is associated with the development of deoxycorticosterone acetate-salt hypertension. The effects of chronic administration of alpha-difluoromethylornithine, a speci
Autor:
Pamela S. Newman, Edward E. Soltis
Publikováno v:
Clinical and Experimental Hypertension. Part A: Theory and Practice. 13:557-572
The present study was performed to determine if chronic administration of a high salt diet induces hypertension similarly in young and adult rats and if treatment with DSP-4 alters the development of the hypertension. Three- (young) and ten- (adult)
Autor:
Shewan M. Aziz, Jack W. Olson, Pamela S. Newman, S. Tofiq, Santosh S. Arcot, Edward E. Soltis, David W. Lipke, Hongtao Guo
Publikováno v:
Clinical and experimental hypertension (New York, N.Y. : 1993). 19(3)
While a number of factors may initiate structural alterations within the cardiovascular system in response to hypertension, there are obligate cellular signaling mechanisms, such as the polyamines, through which they must operate. This study examined
Publikováno v:
American journal of obstetrics and gynecology. 175(6)
This study examined the movement of the soluble ion technetium Tc 99m across the ovine placenta and intramembranous pathway.Nineteen fetal sheep at 131 +/- 1 (SE) days' gestation were studied. After a 1-hour control period technetium Tc 99m was injec
Publikováno v:
American journal of obstetrics and gynecology. 172(5)
Our purpose was to determine whether intraamniotically injected furosemide could be absorbed directly into fetal circulation by the ovine intramembranous pathway.Nine chronically catheterized fetal sheep, five with an intact and four with a surgicall