Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Pamela Rabbitts"'
Autor:
Henry M. Wood, Catherine Daly, Rebecca Chalkley, Burcu Senguven, Lisa Ross, Philip Egan, Preetha Chengot, Jennifer Graham, Neeraj Sethi, Thian K. Ong, Kenneth MacLennan, Pamela Rabbitts, Caroline Conway
Publikováno v:
Genome Medicine, Vol 9, Iss 1, Pp 1-14 (2017)
Abstract Background It is frequently assumed that pre-invasive lesions are simpler precursors of cancer and will contain a limited subset of the genomic changes seen in their associated invasive disease. Driver mutations are thought to occur early, b
Externí odkaz:
https://doaj.org/article/a95699f86abd484fb36ca89057f89acd
Autor:
Lucy F Stead, Stefano Berri, Henry M Wood, Philip Egan, Caroline Conway, Catherine Daly, Kostas Papagiannopoulos, Pamela Rabbitts
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 11, Pp 1075-1086 (2012)
Lung cancer causes more deaths, worldwide, than any other cancer. Several histologic subtypes exist. Currently, there is a dearth of targeted therapies for treating one of the main subtypes: squamous cell carcinoma (SCC). As for many cancers, lung SC
Externí odkaz:
https://doaj.org/article/60499befa5094f9d9ea67e347061fa2b
Autor:
Lucy F Stead, Philip Egan, Aoife Devery, Caroline Conway, Catherine Daly, Stefano Berri, Henry Wood, Ornella Belvedere, Kostas Papagiannopoulos, Anderson Ryan, Pamela Rabbitts
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e78823 (2013)
Squamous cell carcinoma (SCC) of the lung kills over 350,000 people annually worldwide, and is the main lung cancer histotype with no targeted treatments. High-coverage whole-genome sequencing of the other main subtypes, small-cell and adenocarcinoma
Externí odkaz:
https://doaj.org/article/0a9e99c83e624e189049beb7f1b2a024
Autor:
Penny Shaw, Richard Booton, Matthew E.J. Callister, John F. Allen, Marco Novelli, Paul Dhillon, Michael D Peake, Nicholas Counsell, Yenting Ngai, Robert C. Rintoul, Allan Hackshaw, Victoria Ashford-Turner, Simon P. G. Padley, Pamela Rabbitts, Dahmane Oukrif, Andrew G. Nicholson, Asia Ahmed, Kishore Sridharan, Nicholas D. Magee, Sarah Lewis, Mary Falzon, Sam M. Janes, Gabrijela Kocjan, Jeremy George, Nyasha Chinyanganya, Stephen G. Spiro, Chris Griffiths, Pallav L. Shah, Magali Taylor
Publikováno v:
The European Respiratory Journal
Background Low-dose computed tomography (LDCT) screening detects early-stage lung cancer and reduces mortality. We proposed a sequential approach targeted to a high-risk group as a potentially efficient screening strategy. Methods LungSEARCH was a na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fde8a129d29d5a2f30247d0ed6d61d1
https://www.repository.cam.ac.uk/handle/1810/317315
https://www.repository.cam.ac.uk/handle/1810/317315
Autor:
Burcu Sengüven, Henry M. Wood, Lucy F. Stead, Catherine Daly, T.K. Ong, Stefano Berri, Alec S. High, Lisa Ross, Philip Egan, Caroline Conway, Pamela Rabbitts, Jennifer L. Graham, Neeraj Sethi, Rebecca Chalkley, Kenneth A. MacLennan, Preetha Chengot
Publikováno v:
The Journal of Pathology. 237:296-306
The study of the relationships between pre-cancer and cancer and identification of early driver mutations is becoming increasingly important as the value of molecular markers of early disease and personalised drug targets is recognized, especially no
Publikováno v:
Head & Neck. 38:E2395-E2402
Progress in sequencing technology is intrinsically linked to progress in understanding cancer genomics. The purpose of this review was to discuss the development from Sanger sequencing to next-generation sequencing (NGS) technology. We highlight the
Autor:
Marc Debled, Hayssam Soueidan, L. Mauriac, Thomas Bachelot, Justine Rudewicz, Barbara Lortal, Pamela Rabbitts, Hervé Bonnefoi, Richard Iggo, Catherine Daly, Gaëtan MacGrogan, Henry M. Wood, N. Madranges, C. Breton-Callu, Christine Tunon de Lara, Macha Nikolski, N Quenel-Tueux, Audrey Gros, Marina Pulido, M. Fournier, Florence Dalenc
Publikováno v:
British Journal of Cancer
British Journal of Cancer, Cancer Research UK, 2015, pp.bjc.2015.247. ⟨10.1038/bjc.2015.247⟩
British Journal of Cancer, Cancer Research UK, 2015, pp.bjc.2015.247. ⟨10.1038/bjc.2015.247⟩
International audience; BACKGROUND:The aim of this study was to assess the efficacy of neoadjuvant anastrozole and fulvestrant treatment of large operable or locally advanced hormone-receptor-positive breast cancer not eligible for initial breast-con
Autor:
Burcu Sengüven, Paola Cassoni, Rebecca Chalkley, Abdulaziz Al Ajlan, Manar Samman, Philip Egan, T.K. Ong, Pamela Rabbitts, Alec S. High, Catherine Daly, Lisa Ross, Stefano Berri, Caroline Conway, Henry M. Wood, Lucy F. Stead, Sergio Gandolfo, Kenneth A. MacLennan, Monica Pentenero, Preetha Chengot, Adele Cassenti, Alaa Samkari, William Barrett
Publikováno v:
International Journal of Cancer. 137:2364-2373
Verrucous carcinoma of the oral cavity (OVC) is considered a subtype of classical oral squamous cell carcinoma (OSCC). Diagnosis is problematic, and additional biomarkers are needed to better stratify patients. To investigate their molecular signatur
Autor:
Rebecca Chalkley, Lisa Ross, Pamela Rabbitts, Philip Egan, Caroline Conway, Preetha Chengot, Kenneth A. MacLennan, Neeraj Sethi, Jennifer L. Graham, Henry M. Wood, Catherine Daly, T.K. Ong, Burcu Sengüven
Publikováno v:
Genome Medicine
Genome Medicine, Vol 9, Iss 1, Pp 1-14 (2017)
Genome Medicine, Vol 9, Iss 1, Pp 1-14 (2017)
Background It is frequently assumed that pre-invasive lesions are simpler precursors of cancer and will contain a limited subset of the genomic changes seen in their associated invasive disease. Driver mutations are thought to occur early, but it is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5a573df789c12034ca0549f10337522
https://avesis.gazi.edu.tr/publication/details/239774f8-3296-41e0-809b-c7e5a44c3196/oai
https://avesis.gazi.edu.tr/publication/details/239774f8-3296-41e0-809b-c7e5a44c3196/oai
Publikováno v:
International Journal of Cancer. Journal International du Cancer
The catalogue of tumour-specific somatic mutations (SMs) is growing rapidly owing to the advent of next-generation sequencing. Identifying those mutations responsible for the development and progression of the disease, so-called driver mutations, wil