Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Pamela Pantazopoulos"'
Autor:
Mariane Le Fur, Alana Ross, Pamela Pantazopoulos, Nicholas Rotile, Iris Zhou, Peter Caravan, Zdravka Medarova, Byunghee Yoo
Publikováno v:
Cancer Nanotechnology, Vol 12, Iss 1, Pp 1-15 (2021)
Abstract Background In our earlier work, we identified microRNA-10b (miR10b) as a master regulator of the viability of metastatic tumor cells. This knowledge allowed us to design a miR10b-targeted therapeutic consisting of an anti-miR10b antagomir co
Externí odkaz:
https://doaj.org/article/7b7d769c8b584fca8bd0e493831dea3f
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract RNA interference represents one of the most appealing therapeutic modalities for cancer because of its potency, versatility, and modularity. Because the mechanism is catalytic and affects the expression of disease-causing antigens at the pos
Externí odkaz:
https://doaj.org/article/aba3c435f7b44d53a08fc458de111e51
Autor:
Byunghee Yoo, Nikhil Meka, Patrick Sheedy, Ann-Marie Billig, Pamela Pantazopoulos, Zdravka Medarova
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0226356 (2019)
Prior research has shown that critical differences between non-metastatic and metastatic tumor cells are at the level of microRNA. Consequently, harnessing these molecules for the treatment of metastatic cancer could have significant clinical impact.
Externí odkaz:
https://doaj.org/article/3be13adc8eb04672a9fa28565874935c
Tailored chemical reactivity probes for systemic imaging of aldehydes in fibroproliferative diseases
Autor:
Hua Ma, Iris Y. Zhou, Y. Iris Chen, Nicholas J. Rotile, Ilknur Ay, Eman Akam, Huan Wang, Rachel Knipe, Lida P. Hariri, Caiyuan Zhang, Matthew Drummond, Pamela Pantazopoulos, Brianna F. Moon, Avery T. Boice, Samantha E. Zygmont, Jonah Weigand-Whittier, Mozhdeh Sojoodi, Romer A. Gonzalez-Villalobos, Michael K. Hansen, Kenneth K. Tanabe, Peter Caravan
Publikováno v:
bioRxiv
During fibroproliferation, protein-associated extracellular aldehydes are formed by the oxidation of lysine residues on extracellular matrix proteins to form the aldehyde allysine. Here we report three Mn(II)-based, small molecule magnetic resonance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6d774103a098f16a85a8a9c60f945cf
https://doi.org/10.1101/2023.04.20.537707
https://doi.org/10.1101/2023.04.20.537707
Autor:
Zdravka Medarova, Anna Moore, Aseda Tena, Pamela Pantazopoulos, Victoria Petkova, Natalia Barteneva, Kornelia Polyak, Doris P. Tabassum, Ping Wang, Alana Ross, Amol Kavishwar, Byunghee Yoo
Supplementary Fig. S6. Gross anatomical features of mice treated with MN-anti-miR10b and doxorubicin.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24c2f9350dc0a6713e4b365948c2bd06
https://doi.org/10.1158/0008-5472.22407131.v1
https://doi.org/10.1158/0008-5472.22407131.v1
Autor:
Zdravka Medarova, Anna Moore, Aseda Tena, Pamela Pantazopoulos, Victoria Petkova, Natalia Barteneva, Kornelia Polyak, Doris P. Tabassum, Ping Wang, Alana Ross, Amol Kavishwar, Byunghee Yoo
supplemental figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85f5744ffdadc323f85ef8c347d91eef
https://doi.org/10.1158/0008-5472.22407119.v1
https://doi.org/10.1158/0008-5472.22407119.v1
Autor:
Zdravka Medarova, Anna Moore, Aseda Tena, Pamela Pantazopoulos, Victoria Petkova, Natalia Barteneva, Kornelia Polyak, Doris P. Tabassum, Ping Wang, Alana Ross, Amol Kavishwar, Byunghee Yoo
Supplementary Video S8. Physical appearance of mice treated with MN-anti-miR10b/MN-scr-miR and doxorubicin.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6777bfc71dc29627147afca69fbebb1
https://doi.org/10.1158/0008-5472.22407122.v1
https://doi.org/10.1158/0008-5472.22407122.v1
Autor:
Yingying Ning, Iris Yuwen Zhou, Nicholas J. Rotile, Pamela Pantazopoulos, Huan Wang, Stephen Cole Barrett, Mozhdeh Sojoodi, Kenneth K. Tanabe, Peter Caravan
Publikováno v:
Journal of the American Chemical Society. 144(36)
Liver fibrogenesis is accompanied by upregulation of lysyl oxidase enzymes, which catalyze oxidation of lysine ε-amino groups on the extracellular matrix proteins to form the aldehyde containing amino acid allysine (Lys
Autor:
Byunghee Yoo, Mozhdeh Sojoodi, Veronica Clavijo Jordan, Pamela Pantazopoulos, Subrata Ghosh, Peter Caravan, Zdravka Medarova
Publikováno v:
Cancer Research. 83:5069-5069
The recent past has seen impressive progress in the treatment of various malignancies using immunotherapy. One of the most promising approaches involves immune checkpoint inhibition, mainly relying on monoclonal antibodies or small molecules. With sp
Autor:
Iris Y. Zhou, Ilknur Ay, Pamela Pantazopoulos, Alison Wong, Nicholas J. Rotile, Eric M. Gale, Peter Caravan, Ian Ramsay
Publikováno v:
Investigative Radiology. 56:261-270
Objectives Mn-PyC3A is an experimental manganese (Mn)-based extracellular fluid magnetic resonance imaging (MRI) contrast agent that is being evaluated as a direct replacement for clinical gadolinium (Gd)-based contrast agents. The goals of this stud