Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Pamela Ovadje"'
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 18, Iss 4 (2015)
Purpose: Natural products have been a great source of medications used in conventional medicines for the treatment of various diseases; more importantly, they have played a significant role in the development of anti-cancer drugs for a number of deca
Externí odkaz:
https://doaj.org/article/fe8d4e3ca2d2453691df458610238071
Autor:
Kristen Larocque, Pamela Ovadje, Sinisa Djurdjevic, Mariam Mehdi, James Green, Siyaram Pandey
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87064 (2014)
Colchicine, a natural product of Colchicum autumnae currently used for gout treatment, is a tubulin targeting compound which inhibits microtubule formation by targeting fast dividing cells. This tubulin-targeting property has lead researchers to inve
Externí odkaz:
https://doaj.org/article/7bd5158d987b4b878b6e764724d31f63
Autor:
Pamela Ovadje, Dennis Ma, Phillip Tremblay, Alessia Roma, Matthew Steckle, Jose-Antonio Guerrero, John Thor Arnason, Siyaram Pandey
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e113250 (2014)
BACKGROUND:Currently chemotherapy is limited mostly to genotoxic drugs that are associated with severe side effects due to non-selective targeting of normal tissue. Natural products play a significant role in the development of most chemotherapeutic
Externí odkaz:
https://doaj.org/article/7418ae0815cc495ba6031852955f777a
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30604 (2012)
BACKGROUND: Chronic Myelomonocytic Leukemia (CMML) is a heterogeneous disease that is not only hard to diagnose and classify, but is also highly resistant to treatment. Available forms of therapy for this disease have not shown significant effects an
Externí odkaz:
https://doaj.org/article/72bb77f612be4712835ef8df6528f1af
Autor:
Jeremy Y. Ng, Braydon Hall, Roy M. Golsteyn, Pierre S. Haddad, Michael J. Smith, Sharan Sidhu, Pamela Ovadje, John T. Arnason, Halton Quach, Bob Chapman, Cory S. Harris
Publikováno v:
Journal of Natural Health Product Research. 3:1-36
The 17th Annual Natural Health Products Research Conference hosted by the NHP Research Society of Canada (NHPRS) will be held from June 7–9 & 14–16, 2021, virtually hosted by the University of Ottawa, in Ottawa, Ontario. Founded in 2003 by a coll
Publikováno v:
Pancreas. 41:1039-1047
Pancreatic cancer has a 100% mortality rate; the aim of this study is to evaluate the efficacy of dandelion root extract (DRE) in inducing apoptosis and autophagy in aggressive and resistant pancreatic cancer cells.The effect of DRE was evaluated usi
Publikováno v:
Oncotarget
// Pamela Ovadje 1 , Saleem Ammar 2 , Jose-Antonio Guerrero 2, 3 , John Thor Arnason 2 , Siyaram Pandey 1 1 Department of Chemistry & Biochemistry, University of Windsor, Windsor ON, Canada 2 Department of Biology, University of Ottawa, Ottawa ON, Ca
Publikováno v:
Evidence-Based Complementary and Alternative Medicine, Vol 2011 (2011)
Evidence-based Complementary and Alternative Medicine : eCAM
Evidence-based Complementary and Alternative Medicine : eCAM
Notoriously chemoresistant melanoma has become the most prevalent form of cancer for the 25–29 North American age demographic. Standard treatment after early detection involves surgical excision (recurrence is possible), and metastatic melanoma is
Publikováno v:
Journal of Ethnopharmacology. 133:86-91
Aim of study Dandelion extracts have been used in traditional Native American Medicine and Traditional Chinese Medicine (TCM) for treatment of leukemia and breast cancer; however, the mechanism of action remains unknown. Today, DRE is mainly marketed
Autor:
Alessia Roma, Leah Nicoletti, Siyaram Pandey, Pamela Ovadje, Matthew Steckle, John T. Arnason
Publikováno v:
Evidence-Based Complementary and Alternative Medicine, Vol 2015 (2015)
Evidence-based Complementary and Alternative Medicine : eCAM
Evidence-based Complementary and Alternative Medicine : eCAM
Natural health products (NHPs) are defined as natural extracts containing polychemical mixtures; they play a leading role in the discovery and development of drugs, for disease treatment. More than 50% of current cancer therapeutics are derived from