Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Pamela Martinis"'
Autor:
Silvia Grancara, Pamela Martinis, Lisa Dalla Via, Yuta Kanamori, Aída Nelly García-Argáez, Elena Pacella, Antonio Toninello, Enzo Agostinelli
Publikováno v:
Amino acids. 52(2)
Agmatine (AGM) produces a dual effect on the mitochondrial permeability transition (MPT) mechanism in rat liver mitochondria: at low concentrations, it induces the phenomenon, at high ones, inhibits it. The prevention at high concentrations is eviden
Autor:
Silvia Grancara, Aída Nelly García-Argáez, Lisa Dalla Via, Pamela Martinis, Mariano Martínez-Vázquez, Antonio Toninello
Publikováno v:
Current Pharmaceutical Design. 20:223-244
Mitochondria are the cell powerhouses but also contain the mechanisms leading to cell death. Many signals converge on mitochondria to cause the permeabilization of mitochondrial membranes by the mitochondrial permeability transition (MPT) induction a
Autor:
Lisa Dalla Via, Silvia Grancara, Antonio Toninello, Arianna Adami, Simona Samaritani, Luca Labella, Daniela Belli Dell'Amico, Pamela Martinis, Aída Nelly García-Argáez
Publikováno v:
Bioorganic & Medicinal Chemistry. 21:6965-6972
A convenient synthetic route and the characterization of complexes trans-[PtCl2(L)(PPh3)] (L=Et2NH (2), (PhCH2)2NH (3), (HOCH2CH2)2NH) (4) are reported. The antiproliferative activity was evaluated on three human tumor cell lines. The investigation o
Autor:
Antonio Toninello, Silvia Grancara, Vito Di Noto, Pamela Martinis, Lisa Dalla Via, Stefania Saccoccio, Valentina Battaglia, Marcantonio Bragadin, Maria Angelica Grillo, Enzo Agostinelli
Publikováno v:
Amino Acids. 42:761-768
Agmatine, a divalent diamine with two positive charges at physiological pH, is transported into the matrix of liver mitochondria by an energy-dependent mechanism, the driving force of which is the electrical membrane potential. Its binding to mitocho
Autor:
Annarita Stringaro, Pamela Martinis, Roberto Stevanato, Fabio Vianello, Silvia Grancara, Antonio Toninello, Alberto Macone, Marisa Colone, Maria Luisa Di Paolo, Enzo Agostinelli, Emanuela Bonaiuto
Publikováno v:
Free radical biologymedicine. 81
The uptake of spermine into mammalian mitochondria indicated the need to identify its catabolic pathway in these organelles. Bovine liver mitochondria were therefore purified and their capacity for natural polyamine uptake was verified. A kinetic app
Autor:
Silvia Grancara, Aída Nelly García-Argáez, Pamela Martinis, Enzo Agostinelli, Antonio Toninello, Sabrina Manente, Marcantonio Bragadin, G. Tempera, Lisa Dalla Via
The polyamine spermine is transported into the mitochondrial matrix by an electrophoretic mechanism having as driving force the negative electrical membrane potential (ΔΨ). The presence of phosphate increases spermine uptake by reducing ΔpH and en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9cb96535343a6f2ad4941239d2dc1fa
http://hdl.handle.net/11573/868664
http://hdl.handle.net/11573/868664
Autor:
Pamela Martinis, Antonio Toninello, Lisa Dalla Via, Alessandra Braga, Mariano Martínez-Vázquez, Aída Nelly García-Argáez, Enzo Agostinelli, Silvia Grancara
4β-cinnamoyloxy,1β,3α-dihydroxyeudesm-7,8-ene (CDE) extracted from Verbesina persicifolia induces bioenergetic collapse in rat liver mitochondria (RLM), monitored as a fall in the respiratory control index and ADP/O values. This fall in energy is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2136078f3ceb113074ca7569b7951a16
http://hdl.handle.net/11573/517095
http://hdl.handle.net/11573/517095
Autor:
Pamela Martinis, Antonio Toninello, Silvia Grancara, M. Maritati, Enzo Agostinelli, Marcantonio Bragadin, Valentina Battaglia, L. Zago, Valeria Rizzoli
Melatonin, a metabolic product of the amino acid tryptophan, induces a dose-dependent energy drop correlated with a decrease in the oxidative phosphorylation process in isolated rat liver mitochondria. This effect involves a gradual decrease in the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a9fbd7bedbd9a1b496c3c384fcc205e
http://hdl.handle.net/10278/37070
http://hdl.handle.net/10278/37070
Autor:
Valentina Battaglia, Marcantonio Bragadin, Francesca Zonta, Antonio Toninello, Pamela Martinis, Elena Tibaldi, Silvia Grancara, Anna Maria Brunati, Maria Angelica Grillo, Enzo Agostinelli, G. Tempera
Publikováno v:
Amino Acids
Amino Acids, Springer Verlag, 2012, 42 (2-3), pp.741-9. ⟨10.1007/s00726-011-0990-3⟩
Amino Acids, Springer Verlag, 2012, 42 (2-3), pp.741-9. ⟨10.1007/s00726-011-0990-3⟩
International audience; The polyamine spermine is transported into the matrix of various types of mitochondria by a specific uniporter system identified as a protein channel. This mechanism is regulated by the membrane potential; other regulatory eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1091d9a8ece0fa88fd0d8d8e9f03afd3
http://hdl.handle.net/10278/29259
http://hdl.handle.net/10278/29259