Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Pamela M. Phillips"'
Autor:
Mette C. Schladweiler, Allen D. Ledbetter, Andrew F.M. Johnstone, Samantha J. Snow, Pamela M. Phillips, Urmila P. Kodavanti, Christopher J. Gordon
Publikováno v:
Journal of Toxicology and Environmental Health, Part A. 82:86-98
There is growing interest in understanding how maternal diet might affect the sensitivity of offspring to environmental exposures. Previous studies demonstrated that adult rat offspring (approximately 6-months-old) from dams given a high-fat diet (HF
Autor:
Najwa Haykal-Coates, Samantha J. Snow, Judy H. Richards, Charly King, Leslie C. Thompson, Yong Ho Kim, M. Ian Gilmour, Aimen K. Farraj, Mark Higuchi, Brandi L Martin, Wanda C. Williams, Mette C. Schladweiler, Mehdi S. Hazari, Urmila P. Kodavanti, Pamela M. Phillips
Publikováno v:
Science of The Total Environment. 643:378-391
Wildland fire emissions cause adverse cardiopulmonary outcomes, yet controlled exposure studies to characterize health impacts of specific biomass sources have been complicated by the often latent effects of air pollution. The aim of this study was t
Autor:
Aimen K. Farraj, Leslie C. Thompson, Samantha J. Snow, M. Ian Gilmour, W. Kyle Martin, Molly Harmon, Charly King, Pamela M. Phillips, Najwa Haykal-Coates, Mette C. Schladweiler, Mehdi S. Hazari, Yong Ho Kim, Judy H. Richards, Urmila P. Kodavanti, I. J. George, Brandi L Martin
Publikováno v:
Inhal Toxicol
OBJECTIVE: Previous studies have shown that air pollution exposure primes the body to heightened responses to everyday stressors of the cardiovascular system. The purpose of this study was to examine the utility of postprandial responses to a high ca
Autor:
Samantha J. Snow, Edward D. Karoly, Christopher J. Gordon, Pamela M. Phillips, Urmila P. Kodavanti, Mette C. Schladweiler, Colette N. Miller, Allen D. Ledbetter, Andres R. Henriquez, Katarzyna Broniowska
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-18 (2020)
The influence of maternal high-fat diet (HFD) on metabolic response to ozone was examined in Long-Evans rat offspring. F0 females were fed control diet (CD; 10%kcal from fat) or HFD (60%kcal from fat) starting at post-natal day (PND) 30. Rats were br
Autor:
Katherine L. McDaniel, Jason N. Franklin, Emily Alice Woolard, Virginia C. Moser, Pamela M. Phillips, Christopher J. Gordon
Publikováno v:
Neurotoxicology and Teratology. 63:46-50
Human and animal studies indicate that maternal obesity can negatively impact aspects of metabolism and neurodevelopment in the offspring. Not known, however, is whether maternal exercise can alter these adverse outcomes. In this study, Long-Evans fe
Autor:
Samantha J. Snow, Andrew F.M. Johnstone, Pamela M. Phillips, Christopher J. Gordon, J. E. Schmid, Mette C. Schladweiler, Urmila P. Kodavanti, Allen D. Ledbetter
Publikováno v:
Inhalation Toxicology. 29:239-254
Epidemiological and experimental data suggest that obesity exacerbates the health effects of air pollutants such as ozone (O3). Maternal inactivity and calorically rich diets lead to offspring that show signs of obesity. Exacerbated O3 susceptibility
Autor:
Pamela M. Phillips, Urmilla P Kodavanti, Mette C. Schladweiler, Allan Ledbetter, Andrew F.M. Johnstone, Samantha J. Snow, Christopher J. Gordon
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 312:L100-L109
The prevalence of a sedentary (SED) life style combined with calorically rich diets has spurred the rise in childhood obesity, which, in turn, translates to adverse health effects in adulthood. Obesity and lack of active (ACT) lifestyle may increase
Autor:
Mette C. Schladweiler, Colette N. Miller, Katherine L. McDaniel, Christopher J. Gordon, Pamela M. Phillips, Judy H. Richards, Urmila P. Kodavanti, Erica J. Stewart, Matthew Valdez, Janice A. Dye
Publikováno v:
Journal of the Endocrine Society
Ozone exposure during implantation receptivity reduces fetal growth during gestation. Intrauterine growth restriction is associated with increased metabolic disease risk as offspring age into adulthood. Therefore, the purpose of this study was to inv
Publikováno v:
American Journal of Physiology-Renal Physiology. 310:F426-F431
Time-domain nuclear magnetic resonance (TD-NMR)-based measurement of body composition of rodents is an effective method to quickly and repeatedly measure proportions of fat, lean, and fluid without anesthesia. TD-NMR provides a measure of free water
Publikováno v:
Physiology & Behavior. 153:56-63
Chronic exercise is considered as one of the most effective means of countering symptoms of the metabolic syndrome (MS) such as obesity and hyperglycemia. Rodent models of forced or voluntary exercise are often used to study the mechanisms of MS and