A guide to the BRAIN Initiative Cell Census Network data ecosystem.

Autor: Michael Hawrylycz, Maryann E Martone, Giorgio A Ascoli, Jan G Bjaalie, Hong-Wei Dong, Satrajit S Ghosh, Jesse Gillis, Ronna Hertzano, David R Haynor, Patrick R Hof, Yongsoo Kim, Ed Lein, Yufeng Liu, Jeremy A Miller, Partha P Mitra, Eran Mukamel, Lydia Ng, David Osumi-Sutherland, Hanchuan Peng, Patrick L Ray, Raymond Sanchez, Aviv Regev, Alex Ropelewski, Richard H Scheuermann, Shawn Zheng Kai Tan, Carol L Thompson, Timothy Tickle, Hagen Tilgner, Merina Varghese, Brock Wester, Owen White, Hongkui Zeng, Brian Aevermann, David Allemang, Seth Ament, Thomas L Athey, Cody Baker, Katherine S Baker, Pamela M Baker, Anita Bandrowski, Samik Banerjee, Prajal Bishwakarma, Ambrose Carr, Min Chen, Roni Choudhury, Jonah Cool, Heather Creasy, Florence D'Orazi, Kylee Degatano, Benjamin Dichter, Song-Lin Ding, Tim Dolbeare, Joseph R Ecker, Rongxin Fang, Jean-Christophe Fillion-Robin, Timothy P Fliss, James Gee, Tom Gillespie, Nathan Gouwens, Guo-Qiang Zhang, Yaroslav O Halchenko, Nomi L Harris, Brian R Herb, Houri Hintiryan, Gregory Hood, Sam Horvath, Bingxing Huo, Dorota Jarecka, Shengdian Jiang, Farzaneh Khajouei, Elizabeth A Kiernan, Huseyin Kir, Lauren Kruse, Changkyu Lee, Boudewijn Lelieveldt, Yang Li, Hanqing Liu, Lijuan Liu, Anup Markuhar, James Mathews, Kaylee L Mathews, Chris Mezias, Michael I Miller, Tyler Mollenkopf, Shoaib Mufti, Christopher J Mungall, Joshua Orvis, Maja A Puchades, Lei Qu, Joseph P Receveur, Bing Ren, Nathan Sjoquist, Brian Staats, Daniel Tward, Cindy T J van Velthoven, Quanxin Wang, Fangming Xie, Hua Xu, Zizhen Yao, Zhixi Yun, Yun Renee Zhang, W Jim Zheng, Brian Zingg

Publikováno v: PLoS Biology, Vol 21, Iss 6, p e3002133 (2023)

Characterizing cellular diversity at different levels of biological organization and across data modalities is a prerequisite to understanding the function of cell types in the brain. Classification of neurons is also essential to manipulate cell typ

Externí odkaz: https://doaj.org/article/5683e726eb424a3187544a44691a1d0f

A Model of Binocular Motion Integration in MT Neurons

Autor: Pamela M. Baker, Wyeth Bair

Primate cortical area MT plays a central role in visual motion perception, but models of this area have largely overlooked the binocular integration of motion signals. Recent electrophysiological studies tested binocular integration in MT and found s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::619978edc61fb4ad0da77b1b7375a832
https://europepmc.org/articles/PMC6601923/

Modulation of coherent oscillations in inhibitory networks by anesthetics

Autor: Pamela M. Baker, Frances K. Skinner

Publikováno v: Neurocomputing. :293-299

Experiments in cultured hippocampal cells show that the anesthetic propofol enhances inhibition through its action on the GABAA channel. Inhibitory networks have been shown to synchronize in the 20– 80 Hz range, and this activity correlates with so

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::733cc14631966c5ab5306000ec593d71
https://doi.org/10.1016/s0925-2312(02)00355-7

Frequency switches in inhibitory networks with anesthetics

Autor: Jörg Grigull, Peter S. Pennefather, Pamela M. Baker, Beverley A. Orser, Frances K. Skinner

Publikováno v: Neurocomputing. :467-474

We examine how synaptic depression resulting from desensitization (as modelled by a kinetic scheme for GABAA synapses), affects the coherent frequency produced by inhibitory networks. Analytical work using a phenomenological model of synaptic depress

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d05a853fc5e827c5372a3417ec196873
https://doi.org/10.1016/s0925-2312(01)00385-x

11q21.1-11q23.3 Is a site of intrinsic genomic instability triggered by irradiation

Autor: Christine Bien, Shyh Jen Shih, To Uyen Do, Carol M. Bier-Laning, Manual O. Diaz, Nga Du, Andrew T M Vaughan, Sheetal Singh, Pamela M. Baker

Publikováno v: Genes, chromosomescancer. 49(9)

The chromosome location, 11q21-23, is linked to loss of heterozygosity (LOH) in multiple tumors including those of breast, lung, and head and neck. To examine the process of LOH induction, the H292 cell line (human muco-epidermoid carcinoma) was irra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbe2459fa45ce348f19612b6d9730eaa
https://pubmed.ncbi.nlm.nih.gov/20607707