Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Pamela Lockyer"'
Autor:
Natthakan Thongon, Feiyang Ma, Natalia Baran, Pamela Lockyer, Jintan Liu, Christopher Jackson, Ashley Rose, Ken Furudate, Bethany Wildeman, Matteo Marchesini, Valentina Marchica, Paola Storti, Giannalisa Todaro, Irene Ganan-Gomez, Vera Adema, Juan Jose Rodriguez-Sevilla, Yun Qing, Min Jin Ha, Rodrigo Fonseca, Caleb Stein, Caleb Class, Lin Tan, Sergio Attanasio, Guillermo Garcia-Manero, Nicola Giuliani, David Berrios Nolasco, Andrea Santoni, Claudio Cerchione, Carlos Bueso-Ramos, Marina Konopleva, Philip Lorenzi, Koichi Takahashi, Elisabet Manasanch, Gabriella Sammarelli, Rashmi Kanagal-Shamanna, Andrea Viale, Marta Chesi, Simona Colla
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract DNA damage resistance is a major barrier to effective DNA-damaging therapy in multiple myeloma (MM). To discover mechanisms through which MM cells overcome DNA damage, we investigate how MM cells become resistant to antisense oligonucleotide
Externí odkaz:
https://doaj.org/article/0ff32e3e332a47feb2ca0404a6595cec
Autor:
Natthakan Thongon, Feiyang MA, Pamela Lockyer, Natalia Baran, Jintan Liu, Caleb Class, Lin Tan, Paola Storti, Valentina Marchica, Irene Ganan-Gomez, Bethany Wildeman, Vera Adema, Philip Lorenzi, Rodrigo Fonseca, Marta Chesi, Elisabeth Manasanch, Andrea Viale, Simona Colla
Publikováno v:
HemaSphere, Vol 7, p e91269c8 (2023)
Externí odkaz:
https://doaj.org/article/8fa9d000b6b94fada3a3a87be89c2365
Autor:
Natthakan Thongon, Feiyang Ma, Andrea Santoni, Matteo Marchesini, Elena Fiorini, Ashley Rose, Vera Adema, Irene Ganan-Gomez, Emma M. Groarke, Fernanda Gutierrez-Rodrigues, Shuaitong Chen, Pamela Lockyer, Sarah Schneider, Carlos Bueso-Ramos, Guillermo Montalban-Bravo, Caleb A. Class, Kelly A. Soltysiak, Matteo Pellegrini, Ergun Sahin, Alison A. Bertuch, Courtney D. DiNardo, Guillermo Garcia-Manero, Neal S. Young, Karen Dwyer, Simona Colla
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
.This is not the summary of the paper
Externí odkaz:
https://doaj.org/article/9503853908794f3daaa114256931676a
Autor:
Hui-Hua Li, Monte S. Willis, Pamela Lockyer, Nathaniel Miller, Holly McDonough, David J. Glass, Cam Patterson
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/19e7cd96401f4cd6a4a35c1deeaa80f2
Autor:
Hua Mao, Pamela Lockyer, Luge Li, Christie M. Ballantyne, Cam Patterson, Liang Xie, Xinchun Pi
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
LDL receptor-related protein 1 (LRP1) is an endocytic receptor involved in cell signalling and energy homeostasis. Here Maoet al. demonstrate that endothelial Lrp1 modulates lipid and glucose metabolism by binding the nuclear receptor Pparγ and prom
Externí odkaz:
https://doaj.org/article/9568598d8eac4446926e96a6f3554058
Autor:
Laura Dyer, Pamela Lockyer, Yaxu Wu, Arnab Saha, Chelsea Cyr, Martin Moser, Xinchun Pi, Cam Patterson
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0207504 (2018)
[This corrects the article DOI: 10.1371/journal.pone.0139209.].
Externí odkaz:
https://doaj.org/article/6696bbbe3d44486fa2d9f89a2462a69a
Autor:
David S. Lalush, Anka N. Veleva, Laura A. Dyer, Pamela Lockyer, Hong Yuan, C. Brandon Frederick, Cam Patterson
Publikováno v:
Molecules, Vol 18, Iss 5, Pp 5594-5610 (2013)
Angiogenesis plays a key role in cancer progression and correlates with disease aggressiveness and poor clinical outcomes. Affinity ligands discovered by screening phage display random peptide libraries can be engineered to molecularly target tumor b
Externí odkaz:
https://doaj.org/article/434ef8182a964933b1e6281b32d2e2e2
Autor:
Cam Patterson, David S. Lalush, Hong Yuan, Pamela Lockyer, Jacob Schwab, Desh B. Nepal, C. Brandon Frederick, Anka N. Veleva
Publikováno v:
Molecules, Vol 16, Iss 1, Pp 900-914 (2011)
We developed a screening procedure to identify ligands from a phage display random peptide library that are selective for circulating bone marrow derived cells homing to angiogenic tumors. Panning the library on blood outgrowth endothelial cell suspe
Externí odkaz:
https://doaj.org/article/8c8a3bc6d1974d2cb926601eab339f2f
Autor:
Saranya Ravi, Traci L. Parry, Monte S. Willis, Pamela Lockyer, Cam Patterson, James R. Bain, Robert D. Stevens, Olga R. Ilkayeva, Christopher B. Newgard, Jonathan C. Schisler
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 5, Iss 3, p 43 (2018)
We previously reported how the loss of CHIP expression (Carboxyl terminus of Hsc70-Interacting Protein) during pressure overload resulted in robust cardiac dysfunction, which was accompanied by a failure to maintain ATP levels in the face of increase
Externí odkaz:
https://doaj.org/article/73558a233eef49d58fdc75699f30693c
Autor:
Laura Dyer, Pamela Lockyer, Yaxu Wu, Arnab Saha, Chelsea Cyr, Martin Moser, Xinchun Pi, Cam Patterson
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0139209 (2015)
Formation of the cardiac valves is an essential component of cardiovascular development. Consistent with the role of the bone morphogenetic protein (BMP) signaling pathway in cardiac valve formation, embryos that are deficient for the BMP regulator B
Externí odkaz:
https://doaj.org/article/4d20e79d2f4244359c1dc303a83c803d