Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Pamela Lindholm"'
Autor:
Kirsi Vuorinen, Kaisa Salmenkivi, Vuokko L. Kinnula, Pamela Lindholm, Witold Mazur, Marjukka Myllärniemi
Publikováno v:
APMIS. 118:703-712
Human idiopathic pulmonary fibrosis (IPF) and non-specific interstitial pneumonia (NSIP) have been proposed to be attributable to oxidative stress. The nuclear factor, erythroid derived 2, like protein (NRF2)-sulfiredoxin-1 (SRX1) pathway was hypothe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::406c10f274ad3a5916ccf7dfa5afe607
https://doi.org/10.1111/j.1600-0463.2010.02646.x
https://doi.org/10.1111/j.1600-0463.2010.02646.x
Autor:
Andrew G. Nicholson, Kaisa Salmenkivi, Leo Lahti, Izhar Bagwan, Sakari Knuutila, Mohamed Guled, Pamela Lindholm
Publikováno v:
Genes, Chromosomes and Cancer. 48:615-623
Malignant mesothelioma (MM) is an aggressive cancer arising from mesothelial cells, mainly due to former asbestos exposure. Little is known about the microRNA (miRNA) expression of MM. miRNAs are small noncoding RNAs, which play an essential role in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1fe58c31e84d05000cb98737b63f888
https://doi.org/10.1002/gcc.20669
https://doi.org/10.1002/gcc.20669
Autor:
Pamela Lindholm, Hanna Vauhkonen, A G Nicholson, Sisko Anttila, Vuokko L. Kinnula, Sakari Knuutila, Kaisa Salmenkivi
Publikováno v:
Cytogenetic and Genome Research. 119:46-52
Conventional cytogenetic analyses and comparative genomic hybridization have revealed a complex and even chaotic nature of chromosomal aberrations in pleural malignant mesothelioma (MM). We set out to describe the complex gene copy number changes and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01867f927c368f23d593e686a79552ee
https://doi.org/10.1159/000109618
https://doi.org/10.1159/000109618
Autor:
Witold, Mazur, Pamela, Lindholm, Kirsi, Vuorinen, Marjukka, Myllärniemi, Kaisa, Salmenkivi, Vuokko L, Kinnula
Publikováno v:
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 118(9)
Human idiopathic pulmonary fibrosis (IPF) and non-specific interstitial pneumonia (NSIP) have been proposed to be attributable to oxidative stress. The nuclear factor, erythroid derived 2, like protein (NRF2)-sulfiredoxin-1 (SRX1) pathway was hypothe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::039e70d809c738b1c71fa4ad6aa2bb77
https://pubmed.ncbi.nlm.nih.gov/20718723
https://pubmed.ncbi.nlm.nih.gov/20718723
Autor:
Pamela Lindholm, Katri Koli, Marjukka Myllärniemi, Vuokko L. Kinnula, Jorma Keski-Oja, Ylermi Soini, Kaisa Salmenkivi, Piia Vehviläinen
Publikováno v:
Human pathology. 42(2)
Malignant mesothelioma is an aggressive cancer of the pleura with poor prognosis. There is a need to identify new biomarkers and therapeutic targets for this invasive and fatal disease. Transforming growth factor β (TGF-β) can promote mesothelioma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b225839e58f75e721240d7d8c940ec7
https://pubmed.ncbi.nlm.nih.gov/21106222
https://pubmed.ncbi.nlm.nih.gov/21106222
Autor:
Ylermi Soini, Kaisa Salmenkivi, Pamela Lindholm, Vuokko L. Kinnula, Sakari Knuutila, Markku Heikinheimo, Marjukka Myllärniemi
Publikováno v:
Journal of clinical pathology. 62(4)
Background: Malignant mesothelioma (MM) is a highly aggressive tumour with poor prognosis and limited response to therapy. New markers for the prediction of prognosis in MM and in pulmonary adenocarcinoma of the pleura are valuable. GATA-6 belongs to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f9d9c788b72f2d4ce0f2e6dc56102ab
https://pubmed.ncbi.nlm.nih.gov/19060016
https://pubmed.ncbi.nlm.nih.gov/19060016
Autor:
Katri Koli, Tim D. Oury, Corrine R. Kliment, Pamela Lindholm, Kaisa Salmenkivi, Jorma Keski-Oja, Merja Johanna Ryynänen, Marjukka Myllärniemi, Vuokko L. Kinnula
Members of the transforming growth factor (TGF)-beta superfamily, including TGF-betas and bone morphogenetic proteins (BMPs), are essential for the maintenance of tissue homeostasis and regeneration after injury. We have observed that the BMP antagon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32393553181d5b107324451c52a10899
https://europepmc.org/articles/PMC2218851/
https://europepmc.org/articles/PMC2218851/
Autor:
Sakari Knuutila, Gabriella Serio, Marina Musti, Domenica Cavone, Pamela Lindholm, Eeva Kettunen, Silvano Dragonieri
Publikováno v:
Cancer genetics and cytogenetics. 170(1)
Malignant mesothelioma (MM) results from the accumulation of a number of acquired genetic events, especially deletions, which lead to the inactivation of multiple onco-suppressor genes in a multistep cascade mechanism. Past asbestos exposure represen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16c7682894b363a47dad2eed5ab39b1a
https://pubmed.ncbi.nlm.nih.gov/16965949
https://pubmed.ncbi.nlm.nih.gov/16965949
Publikováno v:
Lung Cancer. 54:S25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e186c2228b2805fd31b872c9f1e21445
https://doi.org/10.1016/s0169-5002(07)70178-2
https://doi.org/10.1016/s0169-5002(07)70178-2
Autor:
Jaakko Hollmén, Pamela Lindholm, Sisko Anttila, Penny Nymark, Samuel Kaski, Mikko Korpela, Sakari Knuutila, Salla Ruosaari, Leo Lahti, Vuokko L. Kinnula
Publikováno v:
BMC Genomics
BMC Genomics, Vol 8, Iss 1, p 62 (2007)
BMC Genomics, Vol 8, Iss 1, p 62 (2007)
Background Asbestos has been shown to cause chromosomal damage and DNA aberrations. Exposure to asbestos causes many lung diseases e.g. asbestosis, malignant mesothelioma, and lung cancer, but the disease-related processes are still largely unknown.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::256ca2e0f9429e8fdc5aa3f438e90c05