Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Pamela L. Crowell"'
Autor:
Pamela L. Crowell, C. Max Schmidt, Michele T. Yip-Schneider, Jesse J. Savage, Dean A. Hertzler, II, William O. Cummings
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 8, Iss 6, Pp 437-445 (2006)
Cyclooxygenase-2 (COX-2) has been implicated in the development of gastrointestinal malignancies. The aim of the present study was to determine COX-2 expression/activity throughout stages of experimental and human pancreatic neoplasia. COX-2 immunohi
Externí odkaz:
https://doaj.org/article/c7b71d7522ca4d448b64ae5da21cbb30
Autor:
Oscar W. Cummings, Loehrer J. Patrick Sr., James A. Madura, Pamela L. Crowell, Jesus M. Matos, C. Max Schmidt, Eric A. Wiebke, Howard J. Thomas
Publikováno v:
Journal of Surgical Research. 147:194-199
Background Chemotherapy has been largely unsuccessful in pancreatic cancer. Measurement of cell-specific biological endpoints may clarify the evaluation of a newer generation of compounds. Perillyl alcohol has shown chemotherapeutic activity in precl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2071cf841a3557d15fafb6d0bfe7e9c3
https://doi.org/10.1016/j.jss.2008.02.005
https://doi.org/10.1016/j.jss.2008.02.005
Publikováno v:
Journal of Histochemistry & Cytochemistry. 54:1401-1412
Recent evidence suggests that the PRL-1 and −2 phosphatases may be multifunctional enzymes with diverse roles in a variety of tissue and cell types. Northern blotting has previously shown widespread expression of both transcripts; however, little i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff3690869e004afe567a7013e3bd6cab
https://doi.org/10.1369/jhc.6a7019.2006
https://doi.org/10.1369/jhc.6a7019.2006
Autor:
William O. Cummings, Jesse J. Savage, Michele T. Yip-Schneider, Pamela L. Crowell, Dean A. Hertzler Ii, C. Max Schmidt
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 8, Iss 6, Pp 437-445 (2006)
Cyclooxygenase-2 (COX-2) has been implicated in the development of gastrointestinal malignancies. The aim of the present study was to determine COX-2 expression/activity throughout stages of experimental and human pancreatic neoplasia. COX-2 immunohi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcf36c4fbdfdc82c573e31fe7ca87105
http://www.sciencedirect.com/science/article/pii/S1476558606800266
http://www.sciencedirect.com/science/article/pii/S1476558606800266
Autor:
Pamela L. Crowell, You Rong Lou, Weichung Joe Shih, Xiao Xing Cui, Annette Hansson, Junghan Suh, Allan H. Conney, Yong Lin, Xi Zheng, Richard L. Chang, Gina E. Avila, Amanda D. Ryan, Arnold B. Rabson, Yao Ping Lu
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 315:170-187
Treatment of cultured PANC-1, MIA PaCa-2, and BxPC-3 human pancreatic adenocarcinoma cells with 0.1 to 1.6 nM 12-O-tetradecanoylphorbol-13-acetate (TPA) for 96 h inhibited the proliferation of these cells in a dose-dependent manner, and PANC-1 and MI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5edb0ab24a7da8ac1c5a9b746dd14ac
https://doi.org/10.1124/jpet.105.087585
https://doi.org/10.1124/jpet.105.087585
Autor:
Matthew W. DeCamp, Pamela L. Crowell, Paul A. Lee, Dring N. Crowell, Sean R Werner, Stephen K. Randall
Publikováno v:
Cancer Letters. 202:201-211
Human PRL-1, PRL-2, and PRL-3 tyrosine phosphatases induce the malignant transformation of epithelial cells. We tested the hypothesis that the oncogenic effects of PRL occur by increasing cellular proliferation. Cells stably transfected with PRL-1 or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8df477b7f3ea65ce4c5b4a62e541a189
https://doi.org/10.1016/s0304-3835(03)00517-2
https://doi.org/10.1016/s0304-3835(03)00517-2
Autor:
Christopher Sweeney, Pamela L. Crowell, Darlene S. Barnard, Steven J. Marshall, Steven D. Billings, Michele T. Yip-Schneider, Douglas K. Heilman, Amy Lin, Mark S. Marshall, Liang Cheng
Publikováno v:
Carcinogenesis. 21:139-146
Cyclooxygenase-2 (COX-2) expression is up-regulated in several types of human cancers and has also been directly linked to carcinogenesis. To investigate the role of COX-2 in pancreatic cancer, we evaluated COX-2 protein expression in primary human p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8929124394a4b8a72cbc7e2211db1377
https://doi.org/10.1093/carcin/21.2.139
https://doi.org/10.1093/carcin/21.2.139
Autor:
Pamela L. Crowell
Publikováno v:
The Journal of Nutrition. 129:775S-778S
Monoterpenes are nonnutritive dietary components found in the essential oils of citrus fruits and other plants. A number of these dietary monoterpenes have antitumor activity. For example, d-limonene, which comprises >90% of orange peel oil, has chem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d452d191c1181ffca78a14711685406
https://doi.org/10.1093/jn/129.3.775s
https://doi.org/10.1093/jn/129.3.775s
Publikováno v:
Lipids. 32:151-156
Fruits and vegetables have protective effects against many human cancers, including pancreatic cancer. Isoprenoids are one class of phytochemicals which have antitumor activity, but little is known about their effects on cancer of the pancreas. We te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a193683e81583db86e36397fce72257
https://doi.org/10.1007/s11745-997-0019-y
https://doi.org/10.1007/s11745-997-0019-y
Autor:
Pamela L. Crowell
Publikováno v:
Tumor Biology.
Human PRL (PTP4A) tyrosine phosphatases include PRL-1, PRL-2 and PRL-3. All of these PRL phosphatases are oncogenic in pancreatic and other epithelial cell types, causing downregulation of p21Waf1/Cip1, accelerated G1 to S transition, invasion, and m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::359599f0606ee360f8e6d0cb42a63e53
https://doi.org/10.1158/1538-7445.panca2012-b70
https://doi.org/10.1158/1538-7445.panca2012-b70