Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Pamela K. Carmines"'
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e70926 (2013)
Estrogens exert a variety of effects in both reproductive and non-reproductive tissues. With the discovery of ERα splice variants, prior assumptions concerning tissue-specific estrogen signaling need to be re-evaluated. Accordingly, we sought to det
Externí odkaz:
https://doaj.org/article/32bea7ee252244cb9c604b40c347a612
Autor:
Pamela K. Carmines, Debra L. Irsik, Melissa J. Romero-Aleshire, Erin M. Chavez, Pascale H. Lane, Rachel W. Fallet, Heddwen L. Brooks
Publikováno v:
American Journal of Physiology-Renal Physiology. 315:F512-F520
Estrogen has been implicated in the regulation of growth and immune function in the kidney, which expresses the full-length estrogen receptor-α (ERα66), its ERα splice variants, and estrogen receptor-β (ERβ). Thus, we hypothesized that these spl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c3810d53c6ed079c048646db2d26518
https://doi.org/10.1152/ajprenal.00231.2017
https://doi.org/10.1152/ajprenal.00231.2017
Autor:
Pamela K. Carmines, Carmen De Miguel, Malgorzata Kasztan, Jeremie M. Lever, David M. Pollock, Jennifer S. Pollock
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1492cf8e008687e64b61ad73c9be5a7d
https://doi.org/10.1096/fasebj.2019.33.1_supplement.866.2
https://doi.org/10.1096/fasebj.2019.33.1_supplement.866.2
Autor:
Pamela K Carmines, Xiaoyan Zhou, Maya Dajee, Kathleen A Sullivan, Shawn P Walsh, Alexander Pasternak
Publikováno v:
Hypertension. 70
The bee venom toxin tertiapin Q (TPQ) evokes tubuloglomerular feedback-independent afferent arteriolar constriction in kidneys from rats with streptozotocin-induced type 1 diabetes (STZ rats). Because TPQ inhibits both Kir1.1 and Kir3.x channels, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7e71e68bc990232f1631f255d3a93e1
https://doi.org/10.1161/hyp.70.suppl_1.068
https://doi.org/10.1161/hyp.70.suppl_1.068
Autor:
Jennifer S. Pollock, Pamela K. Carmines, Carmen De Miguel, William C. Hamrick, Janet L. Hobbs, David M. Pollock
Publikováno v:
Scientific Reports
Endothelin-1 (ET-1) promotes renal damage during cardiovascular disease; yet, the molecular mechanisms involved remain unknown. Endoplasmic reticulum (ER) stress, triggered by unfolded protein accumulation in the ER, contributes to apoptosis and orga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e5f3b9fe1fefd8879ba019b82e41527
https://doi.org/10.1038/srep43152
https://doi.org/10.1038/srep43152
Publikováno v:
Acta Physiologica. 209:148-155
Aim During type 1 diabetes (T1D), the medullary thick ascending limb (mTAL) displays an NADPH oxidase-dependent increase in sodium transport, in concert with increased NO production by NO synthase 1 (NOS1) and NOS2. We hypothesized that NOS1- and/or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7e5ca7a927fed9d99acb6fce83fc8dc
https://doi.org/10.1111/apha.12144
https://doi.org/10.1111/apha.12144
Autor:
Yoshio Kodera, Tsuneo Takenaka, Pamela K. Carmines, Yoshikazu Aoki, Masanori Yokoba, Tadakazu Maeda, Naohito Ishii, Masato Katagiri, Masamichi Oh-Ishi, Tsuyoshi Ichikawa, Hiroyuki Imaizumi, Hideki Ikenagasa
Publikováno v:
Clinical Science (London, England : 1979)
Experiments were performed to evaluate the hypothesis that ACE (angiotensin-converting enzyme) inhibition (enalapril) suppresses 3-NT (3-nitrotyrosine) production in the renal cortex during the early stage of Type 1 DM (diabetes mellitus) in the rat.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f9fd15e4e8d2f7f0ae99255e7222d44
https://doi.org/10.1042/cs20120251
https://doi.org/10.1042/cs20120251
Publikováno v:
Hypertension. 59:431-436
—Type 1 diabetes triggers protein kinase C (PKC)-dependent NADPH oxidase activation in the renal medullary thick ascending limb (mTAL), resulting in accelerated superoxide production. As acute exposure to superoxide stimulates NaCl transport by the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38d0e60d71ebffae6737d21aa885bcc3
https://doi.org/10.1161/hypertensionaha.111.184796
https://doi.org/10.1161/hypertensionaha.111.184796
Autor:
Andrew Abad, Randee Sedaka, Carmen De Miguel, Jeremie M. Lever, Malgorzata Kasztan, Jennifer S. Pollock, Pamela K. Carmines, Chunhua Jin, Michelle Sonnenberger, David M. Pollock
Publikováno v:
Acta Physiol (Oxf)
AIM: Chronic high salt intake exaggerates renal injury and inflammation, especially with the loss of functional ET(B) receptors. Tauroursodeoxycholic acid (TUDCA) is a chemical chaperone and bile salt that is approved for the treatment of hepatic dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28ab60f9218f824a1f51df4c628f9a0d
https://doi.org/10.1111/apha.13227
https://doi.org/10.1111/apha.13227
Publikováno v:
Hypertension. 55:468-473
Type 1 diabetes provokes a protein kinase C (PKC)-dependent accumulation of superoxide anion in the renal medullary thick ascending limb (mTAL). We hypothesized that this phenomenon involves PKC-dependent NAD(P)H oxidase activation. The validity of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b168886b3148cc32b3d4e2c351ed112
https://doi.org/10.1161/hypertensionaha.109.145714
https://doi.org/10.1161/hypertensionaha.109.145714