Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Pamela J. Urrutia"'
Publikováno v:
Antioxidants, Vol 12, Iss 2, p 214 (2023)
Protein aggregation, mitochondrial dysfunction, iron dyshomeostasis, increased oxidative damage and inflammation are pathognomonic features of Parkinson’s disease (PD) and other neurodegenerative disorders characterized by abnormal iron accumulatio
Externí odkaz:
https://doaj.org/article/1d7d30cd1951413a87391120ce20c221
Publikováno v:
Antioxidants, Vol 11, Iss 9, p 1807 (2022)
Selective regional iron accumulation is a hallmark of several neurodegenerative diseases, including Alzheimer’s disease and Parkinson’s disease. The underlying mechanisms of neuronal iron dyshomeostasis have been studied, mainly in a gene-by-gene
Externí odkaz:
https://doaj.org/article/88154fda5feb418081958e0ba9cdc27b
Publikováno v:
Antioxidants, Vol 10, Iss 1, p 61 (2021)
Iron accumulation and neuroinflammation are pathological conditions found in several neurodegenerative diseases, including Alzheimer’s disease (AD) and Parkinson’s disease (PD). Iron and inflammation are intertwined in a bidirectional relationshi
Externí odkaz:
https://doaj.org/article/467c9b1c84564a83a6ef49672c3f7a9b
Publikováno v:
Frontiers in Pharmacology, Vol 5 (2014)
A growing set of observations points to mitochondrial dysfunction, iron accumulation, oxidative damage and chronic inflammation as common pathognomonic signs of a number of neurodegenerative diseases that includes Alzheimer's disease, Huntington dise
Externí odkaz:
https://doaj.org/article/85a0b28b25cf448eb5442bc31e4a30c5
Publikováno v:
The Journal of Neuroscience. 43:2037-2052
Neuronal polarization is a complex molecular process regulated by intrinsic and extrinsic mechanisms. Nerve cells integrate multiple extracellular cues to generate intracellular messengers that ultimately control cell morphology, metabolism, and gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22a7e04c93ac58d1ab905c74c7f289ff
https://doi.org/10.1523/jneurosci.1065-19.2023
https://doi.org/10.1523/jneurosci.1065-19.2023
Autor:
Cecilia Conde, Cristopher Villablanca, Mitsunori Fukuda, Daniel A. Bórquez, Yuta Homma, Christian Gonzalez-Billault, Felipe Bodaleo, Pamela J. Urrutia, Victoria Rozés-Salvador
Publikováno v:
J Neurosci
The acquisition of neuronal polarity is a complex molecular process that depends on changes in cytoskeletal dynamics and directed membrane traffic, regulated by the Rho and Rab families of small GTPases, respectively. However, during axon specificati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca5f4364da481a32c269a8faef60e52f
https://doi.org/10.1523/jneurosci.0633-20.2020
https://doi.org/10.1523/jneurosci.0633-20.2020
Publikováno v:
Antioxidants
Antioxidants, Vol 10, Iss 61, p 61 (2021)
Antioxidants, Vol 10, Iss 61, p 61 (2021)
Iron accumulation and neuroinflammation are pathological conditions found in several neurodegenerative diseases, including Alzheimer’s disease (AD) and Parkinson’s disease (PD). Iron and inflammation are intertwined in a bidirectional relationshi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02106b70c4fd2d63ee614cab7f0071b2
https://pubmed.ncbi.nlm.nih.gov/33419006
https://pubmed.ncbi.nlm.nih.gov/33419006
Autor:
Victoria Rozés-Salvador, Daniel A. Bórquez, Cecilia Conde, Cristopher Villablanca, Mitsunori Fukuda, Pamela J. Urrutia, Christian Gonzalez-Billault, Felipe Bodaleo
The acquisition of neuronal polarity is a complex molecular process that involves several different cellular mechanisms that need to be finely coordinated to define the somatodendritic and axonal compartments. Amongst such mechanisms, cytoskeleton an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cc77334473ffad658cd164389ed3520
https://doi.org/10.1101/2019.12.16.876011
https://doi.org/10.1101/2019.12.16.876011
Autor:
Bruce K. Cassels, Fernanda Lourido, Vicente Castro-Castillo, Pamela J. Urrutia, Olimpo García-Beltrán, Natalia Mena, Marco T. Núñez, Raúl Mena
Publikováno v:
Biochemical and Biophysical Research Communications. 463:787-792
Abundant evidence indicates that iron accumulation, oxidative damage and mitochondrial dysfunction are common features of Huntington's disease, Parkinson's disease, Friedreich's ataxia and a group of disorders known as Neurodegeneration with Brain Ir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fafeabe49173f923a9c4109072b05ab
https://doi.org/10.1016/j.bbrc.2015.06.014
https://doi.org/10.1016/j.bbrc.2015.06.014
Publikováno v:
Mitochondrion. 21:92-105
Synthesis of the iron-containing prosthetic groups-heme and iron-sulfur clusters-occurs in mitochondria. The mitochondrion is also an important producer of reactive oxygen species (ROS), which are derived from electrons leaking from the electron tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46dd9a791222e6e779f0c3b408a04add
https://doi.org/10.1016/j.mito.2015.02.001
https://doi.org/10.1016/j.mito.2015.02.001