Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Pamela J. Fraker"'
Autor:
Pamela J. Fraker, Joan M. Cook-Mills
Publikováno v:
Nutrient Modulation of the Immune Response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d674db719de47aec56968bfdc76879a
https://doi.org/10.1201/9781003066644-9
https://doi.org/10.1201/9781003066644-9
Autor:
Pamela J. Fraker
Publikováno v:
Biochemical and Biophysical Research Communications. 425:510-518
Publikováno v:
Obesity. 20:1057-1065
Class III obesity is associated with chronic inflammation and a variety of changes in immune function. Yet surprisingly little was known about the status of neutrophils that represent the first line of immune defense. The aim of this study was to ass
Publikováno v:
Proceedings of the National Academy of Sciences. 105:2028-2033
Natural glucocorticoids (Gc) produced during stress have profound effects on the immune system. It is well known that Gc induce apoptosis in precursor T and B cells, markedly altering lymphopoiesis. However, it has been noted that marrow myeloid cell
Autor:
Pamela J. Fraker
Publikováno v:
The Journal of Nutrition. 135:359-362
Studies of zinc deficiency (ZD) have become important for demonstrating that nutritional imbalances can readily induce programmed cell death (PCD) or apoptosis in a variety of kinds of cells. In mice, ZD caused a 300% increase in the amount of apopto
Autor:
Louis E. King, Pamela J. Fraker
Publikováno v:
Annual Review of Nutrition. 24:277-298
▪ Abstract Thymic atrophy, lymphopenia, and compromised cell- and antibody-mediated responses that cause increased rates of infections of longer duration are the immunological hallmarks of zinc deficiency (ZD) in humans and higher animals. As the d
Publikováno v:
Toxicology and Applied Pharmacology. 187:69-79
Lipopolysaccharide (LPS) and vomitoxin (VT) synergistically induce glucocorticoid- mediated apoptotic cell death in lymphoid tissues of the mouse. Based on the known effects of glucocorticoids, it was hypothesized that the combined exposure to LPS an
Autor:
Louis E. King, Pamela J. Fraker
Publikováno v:
The Journal of Nutrition. 132:3301-3307
Suboptimal nutriture causes leukopenia, but whether this is related to a modification in hematopoiesis is unknown. A 34-d period of zinc deficiency was used to obtain moderate and severely zinc-deficient (ZD) young adult mice whose bone marrow was ev
Publikováno v:
Cellular Immunology. 220:39-50
The studies herein demonstrate that Interleukin-7 (IL-7) promotes survival of murine pro- and pre-B cells against stress levels of corticosterone (Cs). In short-term, 16-h, bone marrow cultures IL-7 abrogated Cs-induced apoptosis and cell cycle arres
Publikováno v:
The Journal of Nutrition. 132:974-979
Lymphopenia is a characteristic of zinc deficiency, which is associated with massive loss of pre-B and pre-T cells from the primary lymphoid organs of zinc-deficient mice that have elevated serum corticosterone (CS). We examined whether this naturall