Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Pamela J, VandeVord"'
Publikováno v:
Neuroscience Research, Vol 198, Iss , Pp 47-56 (2024)
Brain health is largely dependent on the metabolic regulation of amino acids. Brain injuries, diseases, and disorders can be detected through alterations in free amino acid (FAA) concentrations; and thus, mapping the changes has high diagnostic poten
Externí odkaz:
https://doaj.org/article/c65103bd19d84adbb973e16408b60a1c
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Pain is a complex neuro-psychosocial experience that is internal and private, making it difficult to assess in both humans and animals. In pain research, animal models are prominently used, with rats among the most commonly studied. The rat
Externí odkaz:
https://doaj.org/article/e5a92bf928e446839bd6da8efb118a30
Autor:
Seth C. Boehringer, Tullia V. Johnston, Lina Cortez Kwapisz, Pamela J. VandeVord, Blaise M. Costa
Publikováno v:
Pharmacology Research & Perspectives, Vol 11, Iss 3, Pp n/a-n/a (2023)
Abstract The NMDA subtype of glutamate receptor serves as an attractive drug target for the treatment of disorders evolving from hyper‐ or hypoglutamatergic conditions. Compounds that optimize the function of NMDA receptors are of great clinical si
Externí odkaz:
https://doaj.org/article/bf9ddc7068374ce594afa09b45a6747c
Regional variances depict a unique glial-specific inflammatory response following closed-head injury
Autor:
Michelle R. White, Pamela J. VandeVord
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Mild traumatic brain injuries (mTBI) constitute a significant health concern with clinical symptoms ranging from headaches to cognitive deficits. Despite the myriad of symptoms commonly reported following this injury, there is still a lack of knowled
Externí odkaz:
https://doaj.org/article/e22fea65e62a4ca9832bcd73ca863611
Autor:
Erwin Kristobal Gudenschwager-Basso, Oleksii Shandra, Troy Volanth, Dipan C. Patel, Colin Kelly, Jack L. Browning, Xiaoran Wei, Elizabeth A. Harris, Dzenis Mahmutovic, Alexandra M. Kaloss, Fernanda Guilhaume Correa, Jeremy Decker, Biswajit Maharathi, Stefanie Robel, Harald Sontheimer, Pamela J. VandeVord, Michelle L. Olsen, Michelle H. Theus
Publikováno v:
Cells, Vol 12, Iss 9, p 1248 (2023)
Background: Traumatic brain injury (TBI) remains a significant risk factor for post-traumatic epilepsy (PTE). The pathophysiological mechanisms underlying the injury-induced epileptogenesis are under investigation. The dentate gyrus—a structure tha
Externí odkaz:
https://doaj.org/article/bebfb1ee64114a2ba984cef78cea5921
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 15 (2021)
Long-term neuropsychiatric impairments have become a growing concern following blast-related traumatic brain injury (bTBI) in active military personnel and Veterans. Neuropsychiatric impairments such as anxiety and depression are common comorbidities
Externí odkaz:
https://doaj.org/article/ee0e0c62ac45419596d7329710390ce2
Autor:
Aravind Sundaramurthy, Vivek Bhaskar Kote, Noah Pearson, Gregory M. Boiczyk, Elizabeth M. McNeil, Allison J. Nelson, Dhananjay Radhakrishnan Subramaniam, Jose E. Rubio, Kenneth Monson, Warren N. Hardy, Pamela J. VandeVord, Ginu Unnikrishnan, Jaques Reifman
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Despite years of research, it is still unknown whether the interaction of explosion-induced blast waves with the head causes injury to the human brain. One way to fill this gap is to use animal models to establish “scaling laws” that project obse
Externí odkaz:
https://doaj.org/article/0eba4a26d76b4e2ca588d7b24951df19
Publikováno v:
Biomedicines, Vol 11, Iss 2, p 329 (2023)
Mild blast-induced traumatic brain injury (bTBI) is a modality of injury that has been of major concern considering a large number of military personnel exposed to explosive blast waves. bTBI results from the propagation of high-pressure static blast
Externí odkaz:
https://doaj.org/article/ce3bdaae9b3146caa862bf77365287cc
Autor:
Michelle R. Dickerson, Zachary Stephen Bailey, Susan F. Murphy, Michael J. Urban, Pamela J. VandeVord
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Vestibular impairment has become a frequent consequence following blast-related traumatic brain injury (bTBI) in military personnel and Veterans. Behavioral outcomes such as depression, fear and anxiety are also common comorbidities of bTBI. To accel
Externí odkaz:
https://doaj.org/article/c5c4d7e796bf4e44af371abdbee776eb
Autor:
Nora Hlavac, Pamela J. VandeVord
Publikováno v:
Frontiers in Neurology, Vol 10 (2019)
Primary blast neurotrauma represents a unique injury paradigm characterized by high-rate overpressure effects on brain tissue. One major hallmark of blast neurotrauma is glial reactivity, notably prolonged astrocyte activation. This cellular response
Externí odkaz:
https://doaj.org/article/fc7a179b44f2422fb11a4929532b757c