Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Pamela J, Glass"'
Autor:
Christina L. Gardner, Rebecca A. Erwin-Cohen, Bridget S. Lewis, Russell R. Bakken, Shelley P. Honnold, Pamela J. Glass, Crystal W. Burke
Publikováno v:
Methods and Protocols, Vol 7, Iss 3, p 42 (2024)
Venezuelan (VEE), eastern (EEE), and western (WEE) equine encephalitis viruses are encephalitic New World alphaviruses that cause periodic epizootic and epidemic outbreaks in horses and humans that may cause severe morbidity and mortality. Currently
Externí odkaz:
https://doaj.org/article/9adc199c54e243d488077b26024c26a5
Autor:
Crystal W. Burke, Christina L. Gardner, Aimee I. Goodson, Ashley E. Piper, Rebecca A. Erwin-Cohen, Charles E. White, Pamela J. Glass
Publikováno v:
Viruses, Vol 15, Iss 12, p 2351 (2023)
Venezuelan equine encephalitis virus (VEEV) outbreaks occur sporadically. Additionally, VEEV has a history of development as a biothreat agent. Yet, no FDA-approved vaccine or therapeutic exists for VEEV disease. The sporadic outbreaks present a chal
Externí odkaz:
https://doaj.org/article/3dce1b96f6184ab6ab65c974beeee562
Autor:
Jinny L. Liu, Dan Zabetakis, Christina L. Gardner, Crystal W. Burke, Pamela J. Glass, Emily M. Webb, Lisa C. Shriver-Lake, George P. Anderson, James Weger-Lucarelli, Ellen R. Goldman
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Venezuelan equine encephalitis virus (VEEV) is a mosquito borne alphavirus which leads to high viremia in equines followed by lethal encephalitis and lateral spread to humans. In addition to naturally occurring outbreaks, VEEV is a potential
Externí odkaz:
https://doaj.org/article/2c70083720fb45b09c0986debbe9c28b
Autor:
Xin Hu, Elaine Morazzani, Jaimee R. Compton, Moeshia Harmon, Veronica Soloveva, Pamela J. Glass, Andres Dulcey Garcia, Juan J. Marugan, Patricia M. Legler
Publikováno v:
Viruses, Vol 15, Iss 7, p 1503 (2023)
The Venezuelan equine encephalitis virus (VEEV) nonstructural protein 2 (nsP2) cysteine protease (EC 3.4.22.B79) is essential for viral replication. High throughput in silico/in vitro screening using a focused set of known cysteine protease inhibitor
Externí odkaz:
https://doaj.org/article/fe3af9291db04000914d33dafcbd0818
Autor:
John C Trefry, Franco D Rossi, Michael V Accardi, Brandi L Dorsey, Thomas R Sprague, Suzanne E Wollen-Roberts, Joshua D Shamblin, Adrienne E Kimmel, Pamela J Glass, Lynn J Miller, Crystal W Burke, Anthony P Cardile, Darci R Smith, Sina Bavari, Simon Authier, William D Pratt, Margaret L Pitt, Farooq Nasar
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 6, p e0009424 (2021)
Most alphaviruses are mosquito-borne and can cause severe disease in humans and domesticated animals. In North America, eastern equine encephalitis virus (EEEV) is an important human pathogen with case fatality rates of 30-90%. Currently, there are n
Externí odkaz:
https://doaj.org/article/c6d1539e38da43f78f4e7ec443930c9c
Autor:
Crystal W. Burke, Rebecca A. Erwin-Cohen, Aimee I. Goodson, Catherine Wilhelmsen, Jennifer A. Edmundson, Charles E. White, Pamela J. Glass
Publikováno v:
Viruses, Vol 14, Iss 7, p 1502 (2022)
The purpose of this study was to evaluate the effects of the route of administration on the immunogenicity and efficacy of a combined western, eastern, and Venezuelan equine encephalitis (WEVEE) virus-like replicon particle (VRP) vaccine in cynomolgu
Externí odkaz:
https://doaj.org/article/9d67e6a758bc449a8778f33af4bc844f
Autor:
Jinny L. Liu, Emily M. Webb, Dan Zabetakis, Crystal W. Burke, Christina L. Gardner, Pamela J. Glass, Patricia M. Legler, James Weger-Lucarelli, George P. Anderson, Ellen R. Goldman
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
A single domain antibody (clone CC3) previously found to neutralize a vaccine strain of the chikungunya virus (PRNT50 = 2. 5 ng/mL) was found to be broadly neutralizing. Clone CC3 is not only able to neutralize a wild-type (WT) strain of chikungunya
Externí odkaz:
https://doaj.org/article/29c401c161464a698b0ccea2b029bfa3
Autor:
Vanessa Raabe, Lilin Lai, Yong Xu, Chris Huerta, Dongli Wang, Stephanie M. Pouch, Crystal W. Burke, Ashley E. Piper, Christina L. Gardner, Pamela J. Glass, Mark J. Mulligan
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
The human immune response to eastern equine encephalitis virus (EEEV) infection is poorly characterized due to the rarity of infection. We examined the humoral and cellular immune response to EEEV acquired from an infected donor via liver transplanta
Externí odkaz:
https://doaj.org/article/771ca7f64eac4eebb142cd45eec71853
Autor:
Crystal W Burke, Jeffery W Froude, Franco Rossi, Charles E White, Crystal L Moyer, Jane Ennis, M Louise Pitt, Stephen Streatfield, R Mark Jones, Konstantin Musiychuk, Jukka Kervinen, Larry Zeitlin, Vidadi Yusibov, Pamela J Glass
Publikováno v:
PLoS Pathogens, Vol 15, Iss 12, p e1008157 (2019)
There are no FDA licensed vaccines or therapeutics for Venezuelan equine encephalitis virus (VEEV) which causes a debilitating acute febrile illness in humans that can progress to encephalitis. Previous studies demonstrated that murine and macaque mo
Externí odkaz:
https://doaj.org/article/b68e416819474dbc8869926f3c9561c6
Autor:
Chasity D. Andrews, Yang Luo, Ming Sun, Jian Yu, Arthur J. Goff, Pamela J. Glass, Neal N. Padte, Yaoxing Huang, David D. Ho
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 7, Iss C, Pp 74-82 (2017)
Monoclonal antibodies (mAbs) have wide clinical utility, but global access is limited by high costs and impracticalities associated with repeated passive administration. Here, we describe an optimized electroporation-based DNA gene transfer platform
Externí odkaz:
https://doaj.org/article/ac310ef9b08343a4956a922f3c9d2077