Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Pamela Harding"'
Autor:
Yi Tian Yap, Wei Li, Qi Zhou, Sarah Haj-Diab, Dipanwita Dutta Chowdhury, Asmita Vaishnav, Pamela Harding, David C. Williams, Brian F. Edwards, Jerome F. Strauss, Zhibing Zhang
Publikováno v:
Cells, Vol 11, Iss 3, p 336 (2022)
Sperm-associated antigen 6 (SPAG6) is the mammalian orthologue of Chlamydomonas PF16, an axonemal central pair protein involved in flagellar motility. In mice, two Spag6 genes have been identified. The ancestral gene, on mouse chromosome 2, is named
Externí odkaz:
https://doaj.org/article/2edc656554704675b10172db201ca8bf
Autor:
Pablo Nakagawa, Cesar A Romero, Xu Jiang, Martin D'Ambrosio, Ginette Bordcoch, Edward L Peterson, Pamela Harding, Xiao-Ping Yang, Oscar A Carretero
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190300 (2018)
The natural peptide N-Acetyl-Seryl-Aspartyl-Lysyl-Proline (Ac-SDKP) decreases inflammation in chronic diseases such as hypertension and heart failure. However, Ac-SDKP effects on acute inflammatory responses during myocardial infarction (MI) are unkn
Externí odkaz:
https://doaj.org/article/811da24270e44d269b329d4ce32e406a
Publikováno v:
PLoS ONE, Vol 8, Iss 9 (2013)
Externí odkaz:
https://doaj.org/article/fbcf07f64271466c9dc681596342ddf8
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69832 (2013)
Our laboratory reported that male mice with cardiomyocyte-selective knockout of the prostaglandin E2 EP4 receptor sub-type (EP4 KO) exhibit reduced cardiac function. Gene array on left ventricles (LV) showed increased fractalkine, a chemokine implica
Externí odkaz:
https://doaj.org/article/004275dc8ecb4931866600e16ba9dadf
Autor:
Yonghong Man, Wei Li, Yi Tian Yap, Alivia Kearney, Siu‐Pok Yee, Jerome F. Strauss, Pamela Harding, Shizheng Song, Ling Zhang, Zhibing Zhang
Publikováno v:
genesis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6710d2e498422612bd0940f46d208376
https://doi.org/10.1002/dvg.23512
https://doi.org/10.1002/dvg.23512
Publikováno v:
Hypertension. 79
Prostaglandin E 2 is an autacoid that acts through 4 G-protein-coupled receptors (EP1-EP4). We previously reported that expression of the EP3 receptor increases after myocardial infarction (MI) and mediates reduced cardiac function. Moreover, we repo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab5138af968ddca4b6a00b1a14033849
https://doi.org/10.1161/hyp.79.suppl_1.p313
https://doi.org/10.1161/hyp.79.suppl_1.p313
Autor:
DruAnne L. Maxwell, Timothy D. Bryson, David Taube, Jiang Xu, Edward Peterson, Pamela Harding
Publikováno v:
Life sciences. 313
Prostaglandin E2 (PGE2) is a lipid hormone that signals through 4 different G-protein coupled receptor subtypes which act to regulate key physiological processes. Our laboratory has previously reported that PGE2 through its EP3 receptor reduces cardi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00f4627fa3733048c63dce02207673ec
https://pubmed.ncbi.nlm.nih.gov/36521546
https://pubmed.ncbi.nlm.nih.gov/36521546
Autor:
Guodong Pan, Bipradas Roy, Pamela Harding, Thomas Lanigan, Roland Hilgarth, Rajarajan A. Thandavarayan, Suresh Selvaraj Palaniyandi
Publikováno v:
Gene therapy.
Intrinsic activity of aldehyde dehydrogenase (ALDH)2, a cardiac mitochondrial enzyme, is vital in detoxifying 4-hydroxy-2-nonenal (4HNE) like cellular reactive carbonyl species (RCS) and thereby conferring cardiac protection against pathological stre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84e39b79c2652d52c2ba21f0fdc431a0
https://pubmed.ncbi.nlm.nih.gov/35606494
https://pubmed.ncbi.nlm.nih.gov/35606494
Autor:
Pablo A. Ortiz, Pamela Harding, Tengis S. Pavlov, Safa Z Khan, Edward L. Peterson, Jiang Xu, Timothy D Bryson, Teja S Pandrangi
Publikováno v:
Am J Physiol Heart Circ Physiol
Angiotensin II (ANG II) plays a key role in regulating blood pressure and inflammation. Prostaglandin E2 (PGE2) signals through four different G protein-coupled receptors, eliciting a variety of effects. We reported that activation of the EP3 recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3f1d8da30d2dc4ca57edfc2f23a2d53
https://europepmc.org/articles/PMC7191497/
https://europepmc.org/articles/PMC7191497/
Autor:
Pamela Harding, Timothy D. Bryson
Publikováno v:
Biochemical Pharmacology. 195:114858
This review article provides an update for the role of prostaglandin E2 receptors (EP1, EP2, EP3 and EP4) in cardiovascular disease. Where possible we have reported citations from the last decade although this was not possible for all of the topics c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2478fc92fe65a3c5b1b980ed794ef958
https://doi.org/10.1016/j.bcp.2021.114858
https://doi.org/10.1016/j.bcp.2021.114858