Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Pamela Hair"'
Autor:
Kenji Cunnion, Jessica Goss, Pamela Hair, Linda Dell, Destrey Roberson, Ulrich Thienel, Meike Müller, Saskia Carstensen-Aurèche, Philipp Badorrek, Olaf Holz, Jens M. Hohlfeld
Publikováno v:
ERJ Open Research, Vol 10, Iss 4 (2024)
Background This study was a randomised, double-blind, placebo-controlled study intended to establish the translatability of the RLS-0071 mechanisms of action from animal disease models to humans by inhibiting neutrophil-mediated inflammation at the t
Externí odkaz:
https://doaj.org/article/291ea86fe0e24f398dea37888ec168ba
Autor:
Jessica Goss, Pamela Hair, Parvathi Kumar, Giuseppina Iacono, Laura Redden, Gaetano Morelli, Neel Krishna, Ulrich Thienel, Kenji Cunnion
Publikováno v:
Translational Medicine Communications, Vol 8, Iss 1, Pp 1-13 (2023)
Abstract Background RLS-0071 is a novel 15 amino acid peptide dual-targeting anti-inflammatory inhibitor of complement and neutrophil effectors. RLS-0071 inhibits classical complement pathway activation at C1 and blocks the enzymatic activity of myel
Externí odkaz:
https://doaj.org/article/9a63669d6e5b47da9dd36fc9379030b7
Autor:
Adrianne Enos, Parvathi Kumar, Brittany Lassiter, Alana Sampson, Pamela Hair, Neel Krishna, Kenji Cunnion
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0254353 (2021)
Neutrophils are recognized for their role in host defense against pathogens as well as inflammatory conditions mediated through many mechanisms including neutrophil extracellular trap (NET) formation and generation of reactive oxygen species (ROS). N
Externí odkaz:
https://doaj.org/article/b014d657621b4e7ab16b08543e52d520
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0257960 (2021)
Perinatal hypoxic ischemic encephalopathy (HIE) remains a major contributor of infant death and long-term disability worldwide. The role played by the complement system in this ischemia-reperfusion injury remains poorly understood. In order to better
Externí odkaz:
https://doaj.org/article/632e0da05f98427c83b68800875cdff9
Autor:
Jessica M. Goss, Pamela Hair, Parvathi S. Kumar, Ulrich Thienel, Kenji Cunnion, Alexander Ellis
Publikováno v:
American Journal of Case Reports. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef7fd32cd4570326d51a45862cb55fdd
https://doi.org/10.12659/ajcr.939803
https://doi.org/10.12659/ajcr.939803