Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Pamela H.S. Tan"'
Publikováno v:
Journal of Tissue Engineering and Regenerative Medicine. 10:637-646
Anticancer drug discovery has been hampered by the lack of reliable preclinical models, which routinely use cells grown in two-dimensional (2D) culture systems. However, many of the characteristics of cells in 2D culture do not translate into the fin
Publikováno v:
Tissue engineering. Part A. 20(11-12)
The induction of angiogenesis and the promotion of tumor growth and invasiveness are processes critical to metastasis, and are dependent on reciprocal interactions between tumor cells and their microenvironment. The formation of a clinically relevant
Publikováno v:
Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 30(12)
We previously showed that interstitial fluid pressure (IFP) may be an alternate regulator of angiogenesis in solid tumors. Given the accepted link between hypoxia-induced factor and angiogenesis this study investigated the effect of IFP on hypoxia-in
Publikováno v:
Biomaterials. 32(26)
The lack of good preclinical models has hampered anticancer drug discovery. Standard preclinical protocols require the growth of cells in high throughput two-dimensional (2D) culture systems. However, such in vitro drug testing methods yield drug eff