Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Pamela G Robey"'
Autor:
Rose Ann G Franco, Eamonn McKenna, Pamela G Robey, Ross W Crawford, Michael R Doran, Kathryn Futrega
Publikováno v:
Journal of Tissue Engineering, Vol 14 (2023)
For bone marrow stromal cells (BMSC) to be useful in cartilage repair their propensity for hypertrophic differentiation must be overcome. A single day of TGF-β1 stimulation activates intrinsic signaling cascades in BMSCs which subsequently drives bo
Externí odkaz:
https://doaj.org/article/038e51f748e74e648a6b88f612249b43
Autor:
Domenico Raimondo, Cristina Remoli, Letizia Astrologo, Romina Burla, Mattia La Torre, Fiammetta Vernì, Enrico Tagliafico, Alessandro Corsi, Simona Del Giudice, Agnese Persichetti, Giuseppe Giannicola, Pamela G Robey, Mara Riminucci, Isabella Saggio
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0227279 (2020)
Fibrous dysplasia (FD) of bone is a complex disease of the skeleton caused by dominant activating mutations of the GNAS locus encoding for the α subunit of the G protein-coupled receptor complex (Gsα). The mutation involves a substitution of argini
Externí odkaz:
https://doaj.org/article/3a90d042f58b441d85095eb0b8837932
Autor:
Alessandro Corsi, Natasha Cherman, David L Donaldson, Pamela G Robey, Michael T Collins, Mara Riminucci
Publikováno v:
JBMR Plus, Vol 3, Iss 8, Pp n/a-n/a (2019)
ABSTRACT Somatic gain‐of‐function mutations of GNAS cause a spectrum of clinical phenotypes, ranging from McCune‐Albright syndrome (MAS) to isolated disease of bone, endocrine glands, and more rarely, other organs. In MAS, a syndrome classicall
Externí odkaz:
https://doaj.org/article/f8af931cc2394d96b8c1a0d938ea20a8
Autor:
Richard J Chen, Guofeng Zhang, Susan H Garfield, Yi-Jun Shi, Kevin G Chen, Pamela G Robey, Richard D Leapman
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142554 (2015)
Human pluripotent stem cells (hPSCs) represent very promising resources for cell-based regenerative medicine. It is essential to determine the biological implications of some fundamental physiological processes (such as glycogen metabolism) in these
Externí odkaz:
https://doaj.org/article/e9074ddc6fb94cb59548317c753f2712
Autor:
Mitsuaki Ono, Colette A Inkson, Robert Sonn, Tina M Kilts, Luis F de Castro, Azusa Maeda, Larry W Fisher, Pamela G Robey, Agnes D Berendsen, Li Li, Nancy McCartney-Francis, Aaron C Brown, Nigel P S Crawford, Alfredo Molinolo, Alka Jain, Neal S Fedarko, Marian F Young
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71709 (2013)
Prostate cancer (PC) is a leading cause of death in men however the factors that regulate its progression and eventual metastasis to bone remain unclear. Here we show that WISP1/CCN4 expression in prostate cancer tissues was up-regulated in early sta
Externí odkaz:
https://doaj.org/article/d9b68d067f9747fd8bf3cf2c671ad8fb
Autor:
Arun Balakumaran, Edyta Pawelczyk, Jiaqiang Ren, Brian Sworder, Aneeka Chaudhry, Marianna Sabatino, David Stroncek, Joseph A Frank, Pamela G Robey
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11462 (2010)
Superparamagnetic iron oxide nanoparticles (SPION) are increasingly used to label human bone marrow stromal cells (BMSCs, also called "mesenchymal stem cells") to monitor their fate by in vivo MRI, and by histology after Prussian blue (PB) staining.
Externí odkaz:
https://doaj.org/article/4cfc759f74f14bdfbab6b452d921049e
Autor:
Edyta Pawelczyk, Elaine K Jordan, Arun Balakumaran, Aneeka Chaudhry, Nicole Gormley, Melissa Smith, Bobbi K Lewis, Richard Childs, Pamela G Robey, Joseph A Frank
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6712 (2009)
Intracellular labels such as dextran coated superparamagnetic iron oxide nanoparticles (SPION), bromodeoxyuridine (BrdU) or green fluorescent protein (GFP) are frequently used to study the fate of transplanted cells by in vivo magnetic resonance imag
Externí odkaz:
https://doaj.org/article/36b83b61a7f0423b825fa9da68f42fe3
Publikováno v:
Organoids; Volume 2; Issue 2; Pages: 102-119
(1) Background: There are no high-throughput microtissue platforms for generating bone marrow micro-ossicles. Herein, we describe a method for the assembly of arrays of microtissues from bone marrow stromal cells (BMSC) in vitro and their maturation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::4312efd349f1bc90b05d6e160fbd2457
Autor:
Rose Ann G. Franco, Eamonn McKenna, Pamela G. Robey, Md. Shaffiulah Shajib, Ross W. Crawford, Michael R. Doran, Kathryn Futrega
Publikováno v:
Stem Cell Reports. 17:616-632
Bone morphogenetic protein (BMP) cascades are upregulated during bone marrow-derived stromal cell (BMSC) chondrogenesis, contributing to hypertrophy and preventing effective BMSC-mediated cartilage repair. Previous work demonstrated that a proprietar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::613f391256e422b277d300ffb27cb525
https://doi.org/10.1016/j.stemcr.2022.01.016
https://doi.org/10.1016/j.stemcr.2022.01.016
Publikováno v:
Bone. 172:116760
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d522cff557267afd7ccae6ceaf82cb2
https://doi.org/10.1016/j.bone.2023.116760
https://doi.org/10.1016/j.bone.2023.116760