Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Pamela Farrales"'
Autor:
Snehal K. Shukla, Nishant S. Kulkarni, Amanda Chan, Vineela Parvathaneni, Pamela Farrales, Aaron Muth, Vivek Gupta
Publikováno v:
Pharmaceutics, Vol 11, Iss 11, p 559 (2019)
This study aimed at developing metformin hydrochloride (Met) encapsulated liposomal vesicles for enhanced therapeutic outcomes at reduced doses against breast cancer. Liposomal Met was prepared using thin-film hydration through various loading method
Externí odkaz:
https://doaj.org/article/46b6bfc7d4f3493fb47416177968c295
Autor:
Audrey Le Floc’h, Kirsten Nagashima, Dylan Birchard, George Scott, Li-Hong Ben, Dharani Ajithdoss, Kaitlyn Gayvert, Annabel Romero Hernandez, Olivier Herbin, Amanda Tay, Pamela Farrales, Chandrashekhar K. Korgaonkar, Hao Pan, Sweta Shah, Vishal Kamat, Ishita Chatterjee, Jon Popke, Adelekan Oyejide, Wei Keat Lim, Jee H. Kim, Tammy Huang, Matthew Franklin, William Olson, Thomas Norton, Lorah Perlee, George D. Yancopoulos, Andrew J. Murphy, Matthew A. Sleeman, Jamie M. Orengo
Publikováno v:
Science Translational Medicine. 15
The common γ chain (γc; IL-2RG) is a subunit of the interleukin (IL) receptors for the γc cytokines IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. The lack of appropriate neutralizing antibodies recognizing IL-2RG has made it difficult to thoroughly in
Autor:
Audrey Le Floch-Ramondou, Kirsten Nagashima, Pamela Farrales, Amanda Tay, Olivier Herbin, Dharani Ajithdoss, Thomas Norton, Lorah Perlee, Andrew J. Murphy, Matthew Sleeman, Jamie Orengo
Publikováno v:
Blood. 140:473-474
Autor:
Nitesh K. Kunda, Vineela Parvathaneni, Pamela Farrales, Vivek Gupta, Snehal K. Shukla, Aaron Muth, Nishant S. Kulkarni
Publikováno v:
Pharmaceutics
Volume 12
Issue 3
Pharmaceutics, Vol 12, Iss 3, p 206 (2020)
Volume 12
Issue 3
Pharmaceutics, Vol 12, Iss 3, p 206 (2020)
Non-small cell lung cancer (NSCLC) is a global disorder, treatment options for which remain limited with resistance development by cancer cells and off-target events being major roadblocks for current therapies. The discovery of new drug molecules re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1866aaae80dc1f074094871fdb76f52
Autor:
Dipti D. Kanabar, Nishant S. Kulkarni, Vineela Parvathaneni, Pamela Farrales, Vivek Gupta, Snehal K. Shukla, Nitesh K. Kunda, Aaron Muth
Publikováno v:
Pharmaceutical research. 37(3)
This exploration is aimed at developing sorafenib (SF)-loaded cationically-modified polymeric nanoparticles (NPs) as inhalable carriers for improving the therapeutic efficacy of SF against non-small cell lung cancer (NSCLC). The NPs were prepared usi
Autor:
Ehab M. Abo-Ali, Manu Gnanamony, Henna Shah, Joseph Almasri, Dawn Nguyen, Amber M. D'Souza, Younos Otmankel, Mark El Menyewi, Pamela Farrales, Dipti D. Kanabar, Vikas V. Dukhande, Aaron Muth
Publikováno v:
Bioorganicmedicinal chemistry letters. 30(4)
Gankyrin is an oncogenic protein involved in various biological processes, such as cellular growth and proliferation. Its overexpression in certain cancers results in an increase of gankyrin-mediated protein-protein interactions (PPIs), leading to ca
Autor:
Joseph Almasri, Daniel Juang, Abbas Kabir, Nicolas Torrents, Aaron Muth, Amber M. D'Souza, Vikas V. Dukhande, Vivek Gupta, Pamela Farrales, Dipti D. Kanabar, Manu Gnanmony, Snehal K. Shukla
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 30:127372
Gankyrin is an oncoprotein overexpressed in numerous cancer types and appears to play a key role in regulating cell proliferation, cell growth, and cell migration. These roles are largely due to gankyrin's protein-protein interaction with the 26S pro
Autor:
Vineela Parvathaneni, Pamela Farrales, Vivek Gupta, Amanda Chan, Nishant S. Kulkarni, Aaron Muth, Snehal K. Shukla
Publikováno v:
Pharmaceutics
Volume 11
Issue 11
Pharmaceutics, Vol 11, Iss 11, p 559 (2019)
Volume 11
Issue 11
Pharmaceutics, Vol 11, Iss 11, p 559 (2019)
This study aimed at developing metformin hydrochloride (Met) encapsulated liposomal vesicles for enhanced therapeutic outcomes at reduced doses against breast cancer. Liposomal Met was prepared using thin-film hydration through various loading method
Autor:
Pamela Farrales, Aaron Muth
Publikováno v:
Cancer Research. 79:23-23
Introduction: Gankyrin is an oncoprotein involved in regulating numerous pathways important to cell growth, signaling, proliferation and death. The overexpression of gankyrin and subsequent increased protein-protein interactions have been identified