Výsledky vyhledávání - "Pamela E. Paulson"

Concurrent activation of the somatosensory forebrain and deactivation of periaqueductal gray associated with diabetes-induced neuropathic pain

Autor: John W. Wiley, Pamela E. Paulson, Thomas J. Morrow

Publikováno v: Experimental Neurology. 208:305-313

We combined behavioral testing with brain imaging using 99mTc-HMPAO (Amersham Health), to identify CNS structures reflecting alterations in pain perception in the streptozotocin (STZ) model of Type 1 diabetes. We induced diabetic hyperglycemia (blood

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd84a204f331216675695c1df8fe18a6
https://doi.org/10.1016/j.expneurol.2007.09.001

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Early Painful Diabetic Neuropathy Is Associated with Differential Changes in Tetrodotoxin-sensitive and -resistant Sodium Channels in Dorsal Root Ganglion Neurons in the Rat

Autor: John W. Wiley, Thomas J. Morrow, Pamela E. Paulson, Lori L. Isom, Shuangsong Hong

Publikováno v: Journal of Biological Chemistry. 279:29341-29350

Diabetic neuropathy is a common form of peripheral neuropathy, yet the mechanisms responsible for pain in this disease are poorly understood. Alterations in the expression and function of voltage-gated tetrodotoxin-resistant (TTX-R) sodium channels h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4c8e29fc20aa6b83d520ba7bbc9cd21
https://doi.org/10.1074/jbc.m404167200

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Long-term changes in behavior and regional cerebral blood flow associated with painful peripheral mononeuropathy in the rat

Autor: Thomas J. Morrow, Kenneth L. Casey, Pamela E. Paulson

Publikováno v: Pain. 95:31-40

We identified long-term (up to 12 weeks), bilateral changes in spontaneous and evoked pain behavior and baseline forebrain activity following a chronic constriction injury (CCI) of the sciatic nerve. The long-term changes in basal forebrain activatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85a3d2a8cab27c5b29288a2cd80208ab
https://doi.org/10.1016/s0304-3959(01)00370-0

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Chronic, Selective Forebrain Responses to Excitotoxic Dorsal Horn Injury

Autor: Thomas J. Morrow, Robert P. Yezierski, Kenneth L. Casey, Kori L. Brewer, Pamela E. Paulson

Publikováno v: Experimental Neurology. 161:220-226

Intraspinal injection of the AMPA/metabotropic receptor agonist quisqualic acid (QUIS) results in excitotoxic injury which develops pathological characteristics similar to those associated with ischemic and traumatic spinal cord injury (SCI) (R. P. Y

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df1fd3dc3549f55e431aa056bc2d894e
https://doi.org/10.1006/exnr.1999.7246

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Gender differences in pain perception and patterns of cerebral activation during noxious heat stimulation in humans

Autor: Thomas J. Morrow, Kenneth L. Casey, Pamela E. Paulson, Satoshi Minoshima

Publikováno v: Pain. 76:223-229

The purpose of the present study was to determine whether gender differences exist in the forebrain cerebral activation patterns of the brain during pain perception. Accordingly, positron emission tomography (PET) with intravenous injection of H2(15)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1846c731f018eaf0fa7692eb95174d5
https://doi.org/10.1016/s0304-3959(98)00048-7

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Regional Differences in the Effects of Amphetamine Withdrawal on Dopamine Dynamics in the Striatum Analysis of Circadian Patterns Using Automated On-Line Microdialysis

Autor: Terry E. Robinson, Pamela E. Paulson

Publikováno v: Neuropsychopharmacology. 14:325-337

The purpose of the study is to determine the relationship between behavioral symptoms of amphetamine withdrawal and the extracellular concentration of dopamine (DA) in the dorsolateral caudate nucleus and the nucleus accumbens across the entire light

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c47c2d6d41f1e0baa82e5e4d61b5783
https://doi.org/10.1016/0893-133x(95)00141-y

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Amphetamine-Induced time-dependent sensitization of dopamine neurotransmission in the dorsal and ventral striatum: A microdialysis study in behaving rats

Autor: Terry E. Robinson, Pamela E. Paulson

Publikováno v: Synapse. 19:56-65

The purpose of this study was to compare the effects of amphetamine exposure on subsequent amphetamine-induced changes in behavior and dopamine (DA) release in the dorsal and ventral striatum, as a function of time following the discontinuation of re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdc8ff6d04bc8cf03ba9a1cf7066f3f5
https://doi.org/10.1002/syn.890190108

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Psychophysical and cerebral responses to heat stimulation in patients with central pain, painless central sensory loss, and in healthy controls

Autor: Satoshi Minoshima, Michael E. Geisser, Jürgen Lorenz, Kenneth L. Casey, Thomas J. Morrow, Pamela E. Paulson

Publikováno v: Pain, 153, 1772-3; author reply 1773-4
Pain, 153, 8, pp. 1772-3; author reply 1773-4

Patients with central pain (CP) typically have chronic pain within an area of reduced pain and temperature sensation, suggesting an impairment of endogenous pain modulation mechanisms. We tested the hypothesis that some brain structures normally acti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4722800f4b4e1199830a831ad4924db1
http://hdl.handle.net/2066/109226

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