Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Pamela Dean"'
Autor:
Julyanne Brassard, Michael R. Hughes, Pamela Dean, Diana Canals Hernaez, Shelby Thornton, Allyson C. Banville, Julian Smazynski, Mary Warren, Kevin Zhang, Katy Milne, C. Blake Gilks, Anne-Marie Mes-Masson, David G. Huntsman, Brad H. Nelson, Calvin D. Roskelley, Kelly M. McNagny
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionTargeted-immunotherapies such as antibody-drug conjugates (ADC), chimeric antigen receptor (CAR) T cells or bispecific T-cell engagers (eg, BiTE®) all aim to improve cancer treatment by directly targeting cancer cells while sparing healt
Externí odkaz:
https://doaj.org/article/63a8aa00a3774a79b38d00326168392f
Autor:
Diana Canals Hernaez, Michael R. Hughes, Yicong Li, Ilaria Mainero Rocca, Pamela Dean, Julyanne Brassard, Erin M. Bell, Ismael Samudio, Anne-Marie Mes-Masson, Yoshiki Narimatsu, Henrik Clausen, Ola Blixt, Calvin D. Roskelley, Kelly M. McNagny
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Podocalyxin (Podxl) is a CD34-related cell surface sialomucin that is normally highly expressed by adult vascular endothelia and kidney podocytes where it plays a key role in blocking adhesion. Importantly, it is also frequently upregulated on a wide
Externí odkaz:
https://doaj.org/article/24d5b5d683c34d06a8fc6e9fea980efa
Autor:
Blake Gilks, Martin Köbel, Diana Canals Hernaez, Michael R Hughes, Pamela Dean, Peter Bergqvist, Ismael Samudio, Ola Blixt, Katharina Wiedemeyer, Yicong Li, Chris Bond, Eric Cruz, Calvin D Roskelley, Kelly M McNagny
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background The success of new targeted cancer therapies has been dependent on the identification of tumor-specific antigens. Podocalyxin (Podxl) is upregulated on tumors with high metastatic index and its presence is associated with poor outcome, thu
Externí odkaz:
https://doaj.org/article/05e2507cade04908818751ee8569e299
Autor:
Mark D Mathew, Neal D Mathew, Angela Miller, Mike Simpson, Vinci Au, Stephanie Garland, Marie Gestin, Mark L Edgley, Stephane Flibotte, Aruna Balgi, Jennifer Chiang, Guri Giaever, Pamela Dean, Audrey Tung, Michel Roberge, Calvin Roskelley, Tom Forge, Corey Nislow, Donald Moerman
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 10, p e0005058 (2016)
The lack of new anthelmintic agents is of growing concern because it affects human health and our food supply, as both livestock and plants are affected. Two principal factors contribute to this problem. First, nematode resistance to anthelmintic dru
Externí odkaz:
https://doaj.org/article/bf918819764c48fb8380f8fa310027ae
Autor:
Calvin D. Roskelley, Pauline Johnson, Michael R. Gold, T. Michael Underhill, Kelly M. McNagny, Kimberly C. Wiegand, Marie-Renee Blanchet, Jacqueline C.Y. Lai, Pamela Dean, Jawairia Atif, Spencer A. Freeman, Yu-Hsuan Huang, Arif A. Arif
S1. Collagen staining of the inflamed lungs. S2. Extravasation of tumor cells from microvasculature. S3. Effects of methotrexate on the viability of B16F0. S4. MoDM conditioned media enhances the survival of B16F0 cells maintained in suspension cultu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4986d630810dc6fd0706ad16c517b663
https://doi.org/10.1158/1541-7786.22526246.v1
https://doi.org/10.1158/1541-7786.22526246.v1
Autor:
Calvin D. Roskelley, Pauline Johnson, Michael R. Gold, T. Michael Underhill, Kelly M. McNagny, Kimberly C. Wiegand, Marie-Renee Blanchet, Jacqueline C.Y. Lai, Pamela Dean, Jawairia Atif, Spencer A. Freeman, Yu-Hsuan Huang, Arif A. Arif
A rate-limiting step for circulating tumor cells to colonize distant organ sites is their ability to locate a microenvironmental niche that supports their survival and growth. This can be achieved by features intrinsic to the tumor cells and/or by th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::daa7e0cbd2f2d742d4dde7a3371e8873
https://doi.org/10.1158/1541-7786.c.6545042.v1
https://doi.org/10.1158/1541-7786.c.6545042.v1
Autor:
Christopher J.R. Loewen, Calvin D. Roskelley, Kurt Haas, Douglas M. Fowler, Pamela Dean, Kenneth A. Matreyek, Fabian Meili, Warren M. Meyers, Rocio Hollman, Jesse T. Chao
Table S2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::773650e003ac15aa4e5007f3034f8caa
https://doi.org/10.1158/0008-5472.22424944
https://doi.org/10.1158/0008-5472.22424944
Autor:
Christopher J.R. Loewen, Calvin D. Roskelley, Kurt Haas, Douglas M. Fowler, Pamela Dean, Kenneth A. Matreyek, Fabian Meili, Warren M. Meyers, Rocio Hollman, Jesse T. Chao
Supplemental Figure 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43a20b96d1d0a21d2f013575b1cb049e
https://doi.org/10.1158/0008-5472.22424950.v1
https://doi.org/10.1158/0008-5472.22424950.v1
Autor:
Christopher J.R. Loewen, Calvin D. Roskelley, Kurt Haas, Douglas M. Fowler, Pamela Dean, Kenneth A. Matreyek, Fabian Meili, Warren M. Meyers, Rocio Hollman, Jesse T. Chao
As sequencing becomes more economical, we are identifying sequence variations in the population faster than ever. For disease-associated genes, it is imperative that we differentiate a sequence variant as either benign or pathogenic, such that the ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37de9eec82b36e25a4cbc8e6682b0bfe
https://doi.org/10.1158/0008-5472.c.6511906.v1
https://doi.org/10.1158/0008-5472.c.6511906.v1
Autor:
Jawairia Atif, Kimberly C. Wiegand, T. Michael Underhill, Jacqueline C.Y. Lai, Pauline Johnson, Spencer A. Freeman, Michael R. Gold, Kelly M. McNagny, Marie-Renée Blanchet, Arif A. Arif, Calvin D. Roskelley, Pamela Dean, Yu-Hsuan Huang
Publikováno v:
Molecular Cancer Research. 19:2096-2109
A rate-limiting step for circulating tumor cells to colonize distant organ sites is their ability to locate a microenvironmental niche that supports their survival and growth. This can be achieved by features intrinsic to the tumor cells and/or by th