Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Pamela Costner"'
Autor:
Vicky Roy, Wonyeong Jung, Caitlyn Linde, Emily Coates, Julie Ledgerwood, Pamela Costner, Galina Yamshchikov, Hendrik Streeck, Boris Juelg, Douglas A. Lauffenburger, Galit Alter
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-11 (2023)
Abstract Gardasil® (Merck) and Cervarix® (GlaxoSmithKline) both provide protection against infection with Human Papillomavirus 16 (HPV16) and Human Papillomavirus 18 (HPV18), that account for around 70% of cervical cancers. Both vaccines have been
Externí odkaz:
https://doaj.org/article/7cd3ff6b9e2a43718fe51f5ff9ac2cdf
Autor:
Melinda J Hamer, Katherine V Houser, Amelia R Hofstetter, Ana M Ortega-Villa, Christine Lee, Anne Preston, Brooke Augustine, Charla Andrews, Galina V Yamshchikov, Somia Hickman, Steven Schech, Jack N Hutter, Paul T Scott, Paige E Waterman, Mihret F Amare, Victoria Kioko, Casey Storme, Kayvon Modjarrad, Melanie D McCauley, Merlin L Robb, Martin R Gaudinski, Ingelise J Gordon, LaSonji A Holman, Alicia T Widge, Larisa Strom, Myra Happe, Josephine H Cox, Sandra Vazquez, Daphne A Stanley, Tamar Murray, Caitlyn N M Dulan, Ruth Hunegnaw, Sandeep R Narpala, Phillip A Swanson, Manjula Basappa, Jagada Thillainathan, Marcelino Padilla, Britta Flach, Sarah O’Connell, Olga Trofymenko, Patricia Morgan, Emily E Coates, Jason G Gall, Adrian B McDermott, Richard A Koup, John R Mascola, Aurélie Ploquin, Nancy J Sullivan, Julie A Ake, Julie E Ledgerwood, Rebecca Lampley, Brenda Larkin, Pamela Costner, Hope Wilson, Mike Read
Publikováno v:
The Lancet. 401:294-302
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6abe893c24f039ecd7b168efa612fd21
https://doi.org/10.1016/s0140-6736(22)02400-x
https://doi.org/10.1016/s0140-6736(22)02400-x
Autor:
Peifeng Chen, Anita Arthur, Kaitlyn M. Morabito, Kristin Leach, Xiaolin Wang, Grace L. Chen, Attila Nagy, Lauren A. Chang, Jon Cooper, Amy L. Chamberlain, Janel Holland-Linn, Olga Vasilenko, Alicia T. Widge, Shufeng Bai, Judith A Stein, LaSonji A. Holman, Cristina Carter, Iris Pittman, Deepika Gollapudi, Lisa A. Kueltzo, Colleen Fridley, Michelle C. Crank, Amritha Menon, William Whalen, Mridul Ghosh, Cynthia S. Hendel, Martha Nason, Amy Liu, Althaf Hussain, Laura Novik, Pernell Williams, Maria Burgos Florez, Robert T. Bailer, Thuy Nguyen, Brenda Larkin, Tracy J. Ruckwardt, Pamela Costner, Lam Le, Zhong Zhao, Elizabeth Carey, Vera Ivleva, Jennifer Walters, John R. Mascola, Jennifer Cunningham, Olga Trofymenko, Ya-chen Chang, Somia P. Hickman, Martin R. Gaudinski, Richard M. Schwartz, Slobodanka D. Manceva, Kevin Carlton, Barney S. Graham, Rahul Ragunathan, Jason G. D. Gall, Ana M. Ortega-Villa, Colin Tran, Sarah H. Plummer, Abidemi Ola, Ro Shauna S Rothwell, Ingelise J. Gordon, Mingzhong Chen, Jamie G. Saunders, Aba Mensima Eshun, Bob C. Lin, Azad Kumar, Nina M. Berkowitz, Xun Liu, Cora Trelles Cartagena, Emily Phung, Galina Yamshchikov, Joe Horwitz, Sarah O’Connell, Florence Kaltovich, Floreliz Mendoza, LaShawn Requilman, Man Chen, Preeti Apte, Christopher Lee, Renunda Hicks
Publikováno v:
Lancet Respir Med
Multiple active vaccination approaches have proven ineffective in reducing the substantial morbidity and mortality caused by respiratory syncytial virus (RSV) in infants and older adults (aged ≥65 years). A vaccine conferring a substantial and sust
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81ae60b574c97c5be6e3eabd0b1e70f3
https://doi.org/10.1016/s2213-2600(21)00098-9
https://doi.org/10.1016/s2213-2600(21)00098-9
Autor:
Amarendra, Pegu, Sarah E, O'Connell, Stephen D, Schmidt, Sijy, O'Dell, Chloe A, Talana, Lilin, Lai, Jim, Albert, Evan, Anderson, Hamilton, Bennett, Kizzmekia S, Corbett, Britta, Flach, Lisa, Jackson, Brett, Leav, Julie E, Ledgerwood, Catherine J, Luke, Mat, Makowski, Martha C, Nason, Paul C, Roberts, Mario, Roederer, Paulina A, Rebolledo, Christina A, Rostad, Nadine G, Rouphael, Wei, Shi, Lingshu, Wang, Alicia T, Widge, Eun Sung, Yang, John H, Beigel, Barney S, Graham, John R, Mascola, Mehul S, Suthar, Adrian B, McDermott, Nicole A, Doria-Rose, Jae, Arega, Wendy, Buchanan, Mohammed, Elsafy, Binh, Hoang, Rebecca, Lampley, Aparna, Kolhekar, Hyung, Koo, Catherine, Luke, Mamodikoe, Makhene, Seema, Nayak, Rhonda, Pikaart-Tautges, Janie, Russell, Elisa, Sindall, Pratap, Kunwar, Evan J, Anderson, Amer, Bechnak, Mary, Bower, Andres F, Camacho-Gonzalez, Matthew, Collins, Ana, Drobeniuc, Venkata Viswanadh, Edara, Srilatha, Edupuganti, Katharine, Floyd, Theda, Gibson, Cassie M Grimsley, Ackerley, Brandi, Johnson, Satoshi, Kamidani, Carol, Kao, Colleen, Kelley, Hollie, Macenczak, Michele Paine, McCullough, Etza, Peters, Varun K, Phadke, Nadine, Rouphael, Erin, Scherer, Amy, Sherman, Kathy, Stephens, Mehgan, Teherani, Jessica, Traenkner, Juton, Winston, Inci, Yildirim, Lee, Barr, Joyce, Benoit, Barbara, Carste, Joe, Choe, Maya, Dunstan, Roxanne, Erolin, Jana, Ffitch, Colin, Fields, Lisa A, Jackson, Erika, Kiniry, Susan, Lasicka, Stella, Lee, Matthew, Nguyen, Stephanie, Pimienta, Janice, Suyehira, Michael, Witte, Nedim Emil, Altaras, Andrea, Carfi, Marjorie, Hurley, Rolando, Pajon, Wellington, Sun, Tal, Zaks, Rhea N, Coler, Sasha E, Larsen, Kathleen M, Neuzil, Lisa C, Lindesmith, David R, Martinez, Jennifer, Munt, Michael, Mallory, Caitlin, Edwards, Ralph S, Baric, Nina M, Berkowitz, Eli A, Boritz, Kevin, Carlton, Pamela, Costner, Adrian, Creanga, Daniel C, Douek, Martin, Gaudinski, Ingelise, Gordon, LaSonji, Holman, Kwanyee, Leung, Bob C, Lin, Mark K, Louder, Kaitlyn M, Morabito, Laura, Novik, Sarah, O'Connell, Marcelino, Padilla, Phillip A, Swanson, Yi, Zhang, James D, Chappell, Mark R, Denison, Tia, Hughes, Xiaotao, Lu, Andrea J, Pruijssers, Laura J, Stevens, Christine M, Posavad, Michael, Gale, Vineet, Menachery, Pei-Yong, Shi
Publikováno v:
bioRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
SARS-CoV-2 mutations may diminish vaccine-induced protective immune responses, and the durability of such responses has not been previously reported. Here, we present a comprehensive assessment of the impact of variants B.1.1.7, B.1.351, P.1, B.1.429
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e783dd6f4280d48257f617acf459420
https://pubmed.ncbi.nlm.nih.gov/34385356
https://pubmed.ncbi.nlm.nih.gov/34385356
Autor:
Scott A. Rush, Pamela Costner, John R. Mascola, Morgan S.A. Gilman, Yi Zhang, Samuel Darko, Barney S. Graham, Chaim A. Schramm, Alexandrine Derrien-Colemyn, John Misasi, Guillaume Stewart-Jones, Bharat Madan, Peter D. Kwong, Martin R. Gaudinski, Chen-Hsiang Shen, Grace L. Chen, Kaitlyn M. Morabito, Amy Ransier, Jason S. McLellan, Michelle C. Crank, Larissa Ault, Tracy J. Ruckwardt, LaSonji A. Holman, Daniel C. Douek, Sarah A.M. Lucas, Emily Phung, Nina M. Berkowitz, Brandon J. DeKosky, Nicole A. Doria-Rose, Nancy J. Sullivan, Daniel Wrapp, Maryam Mukhamedova, Lingshu Wang, Lauren A. Chang, Somia P. Hickman
Publikováno v:
SSRN Electronic Journal.
An effective vaccine for RSV is an unrealized public health goal. Recently, a single dose of the prefusion-stabilized fusion (F) glycoprotein subunit vaccine (DS-Cav1) was shown to substantially increase serum neutralizing activity in healthy adults.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a753eb36429a1136c8b6be4ec661c83
https://doi.org/10.2139/ssrn.3712702
https://doi.org/10.2139/ssrn.3712702
Autor:
Pamela Costner, Richard E. Stafford, Ingelise J. Gordon, Lindsay S. Garver, Adam DeZure, B. Kim Lee Sim, Christopher V. Plowe, LaSonji A. Holman, Peter F. Billingsley, Barney S. Graham, Stephen L. Hoffman, Floreliz Mendoza, Kathryn L Zephir, Laura Novik, Abraham G. Eappen, Mario Roederer, Martha Nason, Minglin Li, Mary E. Enama, Andrew S. Ishizuka, Robert A. Seder, Julie E. Ledgerwood, Anita Manoj, Nina M. Berkowitz, Jamie G. Saunders, Anusha Gunasekera, Adam Ruben, Barbara J. Flynn, Thomas L. Richie, Matthew B. Laurens, Cynthia S. Hendel, Sarah H. Plummer, Tooba Murshedkar, Andrea A. Berry, Natasha Kc, Tao Li, Kirsten E. Lyke, Sumana Chakravarty, Eric R. James
Publikováno v:
Proceedings of the National Academy of Sciences. 114:2711-2716
A live-attenuated malaria vaccine, Plasmodium falciparum sporozoite vaccine (PfSPZ Vaccine), confers sterile protection against controlled human malaria infection (CHMI) with Plasmodium falciparum (Pf) parasites homologous to the vaccine strain up to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4d58f99fee6c66c32cfa0afb96414f2
https://doi.org/10.1073/pnas.1615324114
https://doi.org/10.1073/pnas.1615324114
Autor:
Martin R Gaudinski, Emily E Coates, Laura Novik, Alicia Widge, Katherine V Houser, Eugeania Burch, LaSonji A Holman, Ingelise J Gordon, Grace L Chen, Cristina Carter, Martha Nason, Sandra Sitar, Galina Yamshchikov, Nina Berkowitz, Charla Andrews, Sandra Vazquez, Carolyn Laurencot, John Misasi, Frank Arnold, Kevin Carlton, Heather Lawlor, Jason Gall, Robert T Bailer, Adrian McDermott, Edmund Capparelli, Richard A Koup, John R Mascola, Barney S Graham, Nancy J Sullivan, Julie E Ledgerwood, Cynthia Starr Hendel, Sarah H. Plummer, Pamela Costner, Jamie Saunders, Floreliz Mendoza, Aba Mensima Eshun, Joseph Casazza, Abidemi Ola, William Whalen, Xiaolin Wang, Jennifer Cunningham, Olga Vasilenko, Catina R. Boyd, Olga Trofymenko, Maria Claudia Burgos Florez, Somia Hickman, Ro Shauna Rothwell, Iris R Pittman, Lam Ngan Le, Brenda D Larkin, Josephine H Cox, Preeti J Apte, Renunda T Hicks, Cora Trelles Cartagena, Pernell V Williams, LaShawn Requilman, Thuy Nguyen, Colin Tran, Michelle Conan-Cibotti, Judy Stein, Tatiana Beresnev
Summary Background mAb114 is a single monoclonal antibody that targets the receptor-binding domain of Ebola virus glycoprotein, which prevents mortality in rhesus macaques treated after lethal challenge with Zaire ebolavirus . Here we present expedit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e7717087e3d9e78889cbb491b0d98d8
https://europepmc.org/articles/PMC6436835/
https://europepmc.org/articles/PMC6436835/
Autor:
Robert T. Bailer, Maria Burgos Florez, Lucio Gama, Sung-Youl Ko, Zonghui Hu, Cynthia S. Hendel, Ro Shauna S Rothwell, Amarendra Pegu, Lily Zhang, Brenda Larkin, Katherine V. Houser, Jennifer Cunningham, Martin R. Gaudinski, Olga Vasilenko, Sandra Sitar, Julie E. Ledgerwood, Nicole A. Doria-Rose, Kathy Zephir, Preeti Apte, KC Cheng, William Whalen, Renunda Hicks, Richard A. Koup, Margarita M. Gomez Lorenzo, Floreliz Mendoza, Xiaolin Wang, Cristina Carter, LaSonji A. Holman, Young Do Kwon, Frank J. Arnold, Hope DeCederfelt, Grace L. Chen, Aryan M. Namboodiri, Peter D. Kwong, Kevin Carlton, Adrian B. McDermott, Joseph P. Casazza, Bob C. Lin, Nina M. Berkowitz, Nilusha Jayasinghe, Laura Novik, Catina R. Boyd, Edmund V. Capparelli, Carol Levinson, Galina Yamshchikov, Cora Trelles Cartagena, Carolyn M. Laurencot, Jason G. D. Gall, Michelle Conan-Cibotti, Sarah H. Plummer, Yunda Huang, Abidemi Ola, Pamela Costner, Ingelise J. Gordon, Janardan P. Pandey, Richard M. Schwartz, Judy Stein, Pernell Williams, Florence Kaltovich, Jamie G. Saunders, Iris Pittman, Milalynn Victorino, John R. Mascola, Barney S. Graham
Publikováno v:
The lancet. HIV. 6(10)
Summary Background Human monoclonal antibodies that potently and broadly neutralise HIV-1 are under development to prevent and treat HIV-1 infection. In this phase 1 clinical trial we aimed to determine the safety, tolerability, and pharmacokinetic p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b775455c935479255ba3131295566fc
https://pubmed.ncbi.nlm.nih.gov/31473166
https://pubmed.ncbi.nlm.nih.gov/31473166
Autor:
Nancy J. Sullivan, Bharat Madan, Emily Phung, John R. Mascola, Barney S. Graham, Chaim A. Schramm, Daniel Wrapp, Jason S. McLellan, Tracy J. Ruckwardt, Daniel C. Douek, John Misasi, Nicole A. Doria-Rose, Lingshu Wang, Pamela Costner, Guillaume Stewart-Jones, Samuel Darko, Maryam Mukhamedova, Amy Ransier, Chen-Hsiang Shen, Martin R. Gaudinski, Sarah A.M. Lucas, Peter D. Kwong, Larissa Ault, Morgan S.A. Gilman, Somia P. Hickman, Yi Zhang, Nina M. Berkowitz, Brandon J. DeKosky, Grace L. Chen, LaSonji A. Holman, Scott A. Rush, Alexandrine Derrien-Colemyn, Kaitlyn M. Morabito, Michelle C. Crank, Lauren A. Chang
Publikováno v:
Immunity
An effective vaccine for respiratory syncytial virus (RSV) is an unrealized public health goal. A single dose of the prefusion-stabilized fusion (F) glycoprotein subunit vaccine (DS-Cav1) substantially increases serum-neutralizing activity in healthy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a46148cb23ee0ab3d39cb8bf4aa72d5c
https://doi.org/10.1016/j.immuni.2021.03.004
https://doi.org/10.1016/j.immuni.2021.03.004
Autor:
Lisa A. Kueltzo, Vrc Study Team, Jonathan W. Cooper, Martin R. Gaudinski, Pamela Costner, Judith A Stein, Syed M. Moin, LaSonji A. Holman, Ingelise J. Gordon, Michelle C. Crank, Grace L. Chen, Lauren A. Chang, Azad Kumar, Nina M. Berkowitz, Juliane P. Hill, Jason S. McLellan, Kevin Carlton, Tracy J. Ruckwardt, Emily Phung, Anthony T. DiPiazza, Somia P. Hickman, Martha Nason, Julie E. Ledgerwood, Jason G. D. Gall, Peter D. Kwong, Galina Yamshchikov, John R. Mascola, Barney S. Graham, Man Chen, Richard M. Schwartz, Peifeng Chen, Kaitlyn M. Morabito
Publikováno v:
Science (New York, N.Y.). 365(6452)
Building a better RSV vaccine Respiratory syncytial virus (RSV) causes severe respiratory disease, especially in infants and the elderly. However, attempts to produce effective human vaccines have largely been unsuccessful. Structure-based design has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29c8918fb635f8ebf132ccf8c9369e0f
https://pubmed.ncbi.nlm.nih.gov/31371616
https://pubmed.ncbi.nlm.nih.gov/31371616