Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Pamela Carroll"'
Autor:
Julie Gorenstein, Ben Zack, Joseph R. Marszalek, Ansu Bagchi, Sai Subramaniam, Pamela Carroll, Cem Elbi
Publikováno v:
BioTechniques, Vol 49, Iss 3, Pp 663-665 (2010)
High-content image analysis captures many cellular parameters, but current methods of interpretation of acquired multiple dimensions assume a normal distribution, which is rarely seen in biological data sets. We describe a novel statistically based a
Externí odkaz:
https://doaj.org/article/4fa1b3545c734e788e4da312f12406bc
Autor:
Kevin Fitzgerald, Svetlana Tertyshnikova, Lisa Moore, Lynn Bjerke, Ben Burley, Jian Cao, Pamela Carroll, Robert Choy, Steve Doberstein, Yves Dubaquie, Yvonne Franke, Jenny Kopczynski, Hendrik Korswagen, Stanley R Krystek, Nicholas J Lodge, Ronald Plasterk, John Starrett, Terry Stouch, George Thalody, Honey Wayne, Alexander van der Linden, Yongmei Zhang, Stephen G Walker, Mark Cockett, Judi Wardwell-Swanson, Petra Ross-Macdonald, Rachel M Kindt
Publikováno v:
PLoS Genetics, Vol 2, Iss 4, p e57 (2006)
We report here on a chemical genetic screen designed to address the mechanism of action of a small molecule. Small molecules that were active in models of urinary incontinence were tested on the nematode Caenorhabditis elegans, and the resulting phen
Externí odkaz:
https://doaj.org/article/1932641b9cd346b58d4f8941da49cf1f
Autor:
Michael O'Keefe, Abha Dhaneshwar, Catarina V. Nogueira, Wendy Broom, Jessica Flechtner, Pamela Carroll, Hanna Starobinets, Jason R. Dobson, James Foti, Erick Donis, Huilei Xu, Hubert Lam, Kyle Ferber, James Loizeaux, Paul Kirschmeier
Publikováno v:
Cancer Research. 78:5718-5718
Neoantigens are emerging as attractive vaccine targets for personalized cancer immunotherapy. As opposed to tumor-associated antigens, neoantigens contain non-synonymous mutations that enable their identification as foreign targets not subject to cen
Autor:
Michael O'Keeffe, Jason R. Dobson, Christopher L. Warren, James Foti, Ning Wu, Jin Yuan, Huilei Xu, Johanna K. Kaufmann, Jessica Flechtner, Pamela Carroll, Kyle Ferber, Crystal Cabral, Wendy Broom, Erick Donis, James Loizeaux
Publikováno v:
Cancer Research. 78:730-730
Neoantigens arise from tumor-specific, somatic mutations and have the potential to be recognized by T cells that are associated with anti-tumor immune responses. Since they are non-self, they are hypothesized to provide an attractive therapeutic moda
Autor:
Pamela Carroll
Publikováno v:
Race Equality Teaching. 22:18-21
Autor:
Theresa Zhang, Christine Kelley, Taha Merghoub, Zheng Yan, Biao Liu, Judy Jacques, Jessica Flechtner, Matthew D. Hellman, Aula Alami, Lila Ghamsari, Timothy A. Chan, Jonathan J. Havel, Emilio Flano, Vladimir Makarov, Jedd D. Wolchok, Pamela Carroll
Publikováno v:
Cancer Research. 77:632-632
Despite the unprecedented efficacy of checkpoint blockade (CPB) therapy in treating some cancers, the majority of patients fail to respond. Several lines of evidence support that the combination of CPB and neoantigen vaccine prolongs survival curves
Autor:
Joseph R. Marszalek, Cem Elbi, Sai Subramaniam, Julie Gorenstein, Ben Zack, Pamela Carroll, Ansu Bagchi
Publikováno v:
BioTechniques. 49(3)
High-content image analysis captures many cellular parameters, but current methods of interpretation of acquired multiple dimensions assume a normal distribution, which is rarely seen in biological data sets. We describe a novel statistically based a
Autor:
Sudhir Rao, Jennifer O'Neil, Lex H.T. Van der Ploeg, Nancy E. Kohl, Peter Strack, Cole Liberator, Pamela Carroll, Theresa Zhang, Victoria M. Richon, Jing Yuan, Xudong Dai, A. Thomas Look, James S. Hardwick, Edyta Tyminski, Christopher Winter, Giulio Draetta
Publikováno v:
Cancer research. 69(7)
NOTCH signaling is deregulated in the majority of T-cell acute lymphoblastic leukemias (T-ALL) as a result of activating mutations in NOTCH1. Gamma secretase inhibitors (GSI) block proteolytic activation of NOTCH receptors and may provide a targeted
Autor:
Clay L. Efferson, Nancy E. Kohl, Cem Elbi, Jennifer Tammam, Pamela Carroll, Pradip K. Majumder
Publikováno v:
The FASEB Journal. 21
The Notch pathway is an evolutionarily conserved regulator of cellular differentiation in many tissues during development and later through adult life. It has been reported that particular cancer t...
Autor:
Pamela Carroll, Arslan Loualich, David Westaway, Muhammad A. Chishti, Saeed Bohlega, Maqbool Ahmed, Christine Sato, Peter St George-Hyslop, Ekaterina Rogaeva
Publikováno v:
Archives of neurology. 63(10)
Background To date, 5 well-confirmed genes for Parkinson disease (PD) have been identified, including 3 autosomal recessive genes: PTEN-induced putative kinase 1 ( PINK1 ), parkin , and DJ-1 . Almost nothing is known about the genetics of PD in Saudi