Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Pamela C. Rosato"'
Autor:
Pamela C. Rosato, Sathi Wijeyesinghe, J. Michael Stolley, Christine E. Nelson, Rachel L. Davis, Luke S. Manlove, Christopher A. Pennell, Bruce R. Blazar, Clark C. Chen, Melissa A. Geller, Vaiva Vezys, David Masopust
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
The immunosuppressive tumor environment and the lack of functional anti-tumor immunity are major limiting factors in immunotherapy. Here the authors show that human and mouse tumors are infiltrated by virus-specific memory T cells, which can be harne
Externí odkaz:
https://doaj.org/article/5f068cea4ece4349a43cb5cd50da3600
Autor:
Kristin S. Fitzpatrick, Hanna N. Degefu, Katrina Poljakov, Madeleine G. Bibby, Allison J. Remington, Tyler G. Searles, Matthew D. Gray, Jim Boonyaratanakornkit, Pamela C. Rosato, Justin J. Taylor
Publikováno v:
The Journal of Immunology. 210:1156-1165
The study of antigen-specific lymphocytes has been a key advancement in immunology the past few decades. The development of multimerized probes containing antigens, peptide:MHC complexes, or other ligands was one innovation allowing the direct study
Autor:
Pamela C. Rosato, Sahar Lotfi-Emran, Vineet Joag, Sathi Wijeyesinghe, Clare F. Quarnstrom, Hanna N. Degefu, Rebecca Nedellec, Jason M. Schenkel, Lalit K. Beura, Lars Hangartner, Dennis R. Burton, David Masopust
Publikováno v:
Mucosal Immunology. 16:17-26
Autor:
Jianfang Ning, Noah V. Gavil, Shaoping Wu, Sathi Wijeyesinghe, Eyob Weyu, Jun Ma, Ming Li, Florina‑Nicoleta Grigore, Sanjay Dhawan, Alexander G. J. Skorput, Shawn C. Musial, Clark C. Chen, David Masopust, Pamela C. Rosato
Publikováno v:
Cancer Immunology, Immunotherapy. 71:2577-2579
Autor:
Ghaidan A. Shamsan, Chao J. Liu, Brooke C. Braman, Susan K. Rathe, Aaron L. Sarver, Nima Ghaderi, Mariah M. McMahon, Rebecca L. Klank, Barbara R. Tschida, S. Joey McFarren, Pamela C. Rosato, David Masopust, Jann N. Sarkaria, H. Brent Clark, Steven S. Rosenfeld, David A. Largaespada, David J. Odde
SUMMARYGlioblastoma remains a deadly cancer driven by invasion of tumor cells into the brain. Transcriptomic analyses have revealed distinct molecular subtypes, but mechanistic differences that explain clinical differences are not clear. Here, we sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d23ad164c074cfa8d8ecf88b97687e16
https://doi.org/10.1101/2022.06.26.497270
https://doi.org/10.1101/2022.06.26.497270
Autor:
Clark C. Chen, Noah V. Gavil, Jianfang Ning, Shaoping Wu, Florina Grigore, David Masopust, Sanjay Dhawan, Ming Li, Pamela C. Rosato, Jun Ma
Publikováno v:
Neuro Oncol
Immunotherapy with the success of checkpoint blockade brings hope for cancer treatment with enduring or complete responses in various types of advanced malignancies, however, it has not benefited a number of so called “cold tumors”, such as gliob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2ed9630e7aa903b07c0e293a88eff6c
https://europepmc.org/articles/PMC8598851/
https://europepmc.org/articles/PMC8598851/
Autor:
Jianfang Ning, Noah V. Gavil, Shaoping Wu, Sathi Wijeyesinghe, Eyob Weyu, Jun Ma, Ming Li, Florina-Nicoleta Grigore, Sanjay Dhawan, Alexander G. J. Skorput, Shawn C. Musial, Clark C. Chen, David Masopust, Pamela C. Rosato
Publikováno v:
Cancer Immunol Immunother
Glioblastoma multiforme (GBM) is among the most aggressive, treatment-resistant cancers, and despite standard of care surgery, radiation and chemotherapy, is invariably fatal. GBM is marked by local and systemic immunosuppression, contributing to res
Autor:
Noah V. Gavil, Jianfang Ning, Shawn C. Musial, Sanjay Dhawan, David Masopust, Shaoping Wu, Pamela C. Rosato, Eyob Weyu, Jun Ma, Florina-Nicoleta Grigore, Alexander G. J. Skorput, Clark C. Chen, Sathi Wijeyesinghe, Ming Li
Glioblastoma multiforme (GBM) is among the most aggressive, treatment resistant cancers, and despite standard of care surgery, radiation and chemotherapy, is invariably fatal. GBM is marked by local and systemic immunosuppression, contributing to res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb9e924c46ad058eeb89f53928fc3ae9
https://doi.org/10.1101/2021.09.06.458939
https://doi.org/10.1101/2021.09.06.458939
Autor:
Pamela C Rosato, David A Leib
Publikováno v:
PLoS Pathogens, Vol 11, Iss 7, p e1005028 (2015)
Interferon (IFN) responses are critical for controlling herpes simplex virus 1 (HSV-1). The importance of neuronal IFN signaling in controlling acute and latent HSV-1 infection remains unclear. Compartmentalized neuron cultures revealed that mature s
Externí odkaz:
https://doaj.org/article/8bd6f9ca6335465ab628f6f2342b4060
Autor:
Shawn C Musial, Tyler G. Searles, Sierra A. Kleist, Hanna N. Degefu, Jordan F. Isaacs, Alexander G. Skorput, Pamela C. Rosato
Publikováno v:
The Journal of Immunology. 208:165.18-165.18
The shifting paradigm regarding immune surveillance of the central nervous system (CNS) has shed light on immune cell networks thought to be absent from healthy brain tissue. Resident memory T cells (TRM) are a unique subset of memory T cells that pe