Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Pamela Basantes"'
Autor:
Sandra Rayego-Mateos, Laura Marquez-Exposito, Pamela Basantes, Lucia Tejedor-Santamaria, Ana B. Sanz, Tri Q. Nguyen, Roel Goldschmeding, Alberto Ortiz, Marta Ruiz-Ortega
Publikováno v:
Antioxidants, Vol 12, Iss 8, p 1541 (2023)
Inflammation is a key characteristic of both acute and chronic kidney diseases. Preclinical data suggest the involvement of the NLRP3/Inflammasome, receptor-interacting protein kinase-3 (RIPK3), and NRF2/oxidative pathways in the regulation of kidney
Externí odkaz:
https://doaj.org/article/5d896169b8334d5e895b9eea1e4e7c5b
Autor:
Sandra Rayego-Mateos, Pamela Basantes, José Luis Morgado-Pascual, Beatriz Brazal Prieto, Beatriz Suarez-Alvarez, Alberto Ortiz, Carlos Lopez-Larrea, Marta Ruiz-Ortega
Publikováno v:
Antioxidants, Vol 12, Iss 5, p 1130 (2023)
Among the mechanisms involved in the progression of kidney disease, mitochondrial dysfunction has special relevance. Epigenetic drugs such as inhibitors of extra-terminal domain proteins (iBET) have shown beneficial effects in experimental kidney dis
Externí odkaz:
https://doaj.org/article/da9ed6c631bd4d0fb30bdba55b41da22
Type IV Collagen and SOX9 Are Molecular Targets of BET Inhibition in Experimental Glomerulosclerosis
Autor:
José Luis Morgado-Pascual, Beatriz Suarez-Alvarez, Vanessa Marchant, Pamela Basantes, Pierre-Louis Tharaux, Alberto Ortiz, Carlos Lopez-Larrea, Marta Ruiz-Ortega, Sandra Rayego-Mateos
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 1; Pages: 486
Progressive glomerulonephritis (GN) is characterized by an excessive accumulation of extracellular (ECM) proteins, mainly type IV collagen (COLIV), in the glomerulus leading to glomerulosclerosis. The current therapeutic approach to GN is suboptimal.